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Chemical Compound Review

PEt3     triethylphosphane

Synonyms: Et3P, AG-F-93974, ACMC-20aje9, CHEBI:39971, Cytop(R) 320, ...
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Disease relevance of triethylphosphane


High impact information on triethylphosphane


Biological context of triethylphosphane


Anatomical context of triethylphosphane


Associations of triethylphosphane with other chemical compounds


Gene context of triethylphosphane


Analytical, diagnostic and therapeutic context of triethylphosphane


  1. The mechanism of acute cytotoxicity of triethylphosphine gold(I) complexes. II. Triethylphosphine gold chloride-induced alterations in mitochondrial function. Rush, G.F., Smith, P.F., Hoke, G.D., Alberts, D.W., Snyder, R.M., Mirabelli, C.K. Toxicol. Appl. Pharmacol. (1987) [Pubmed]
  2. Effects of gold compounds on the function of phagocytic cells. II. Inhibition of superoxide radical generation by tripeptide-activated polymorphonuclear leukocytes. Davis, P., Johnston, C., Miller, C.L., Wong, K. Arthritis Rheum. (1983) [Pubmed]
  3. Early experiences with auranofin in juvenile rheumatoid arthritis. Brewer, E.J., Giannini, E.H., Person, D.A. Am. J. Med. (1983) [Pubmed]
  4. Cellular association, intracellular distribution, and efflux of auranofin via sequential ligand exchange reactions. Snyder, R.M., Mirabelli, C.K., Crooke, S.T. Biochem. Pharmacol. (1986) [Pubmed]
  5. A simplified procedure for the reduction and alkylation of cysteine residues in proteins prior to proteolytic digestion and mass spectral analysis. Hale, J.E., Butler, J.P., Gelfanova, V., You, J.S., Knierman, M.D. Anal. Biochem. (2004) [Pubmed]
  6. The mechanism of acute cytotoxicity of triethylphosphine gold(I) complexes. I. Characterization of triethylphosphine gold chloride-induced biochemical and morphological changes in isolated hepatocytes. Rush, G.F., Smith, P.F., Alberts, D.W., Mirabelli, C.K., Snyder, R.M., Crooke, S.T., Sowinski, J., Jones, H.B., Bugelski, P.J. Toxicol. Appl. Pharmacol. (1987) [Pubmed]
  7. Triethylphosphine gold: cellular uptake and disposition after single and repeated oral doses in rats. Sharma, R.P., Smillie, J., Laverty, R. J. Pharm. Pharmacol. (1984) [Pubmed]
  8. A comparison of tissue gold levels in guinea-pigs after treatment with myocrisin injected intramuscularly and triethylphosphine gold chloride and myocrisin administered orally. Kamel, H., Brown, D.H., Ottaway, J.M., Smith, W.E., Cottney, J., Lewis, A.J. Agents Actions (1978) [Pubmed]
  9. The effect of a new antirheumatic drug, triethylphosphine gold (auranofin), on in vitro lymphocyte and monocyte cytotoxicity. Russell, A.S., Davis, P., Miller, C. J. Rheumatol. (1982) [Pubmed]
  10. Characterization of the in vitro effect of triethylphosphine gold (auranofin) on human NK cell activity. Pedersen, B.K., Abom, B. Clinical and experimental rheumatology. (1986) [Pubmed]
  11. A comparison of the effects of two gold-containing therapeutic agents on articular chondrocyte growth in vitro. Kirkpatrick, C.J., Mohr, W. Rheumatol. Int. (1983) [Pubmed]
  12. Comparative pharmacokinetics of triethylphosphine gold (auranofin) and gold sodium thiomalate (GST). Furst, D.E., Dromgoole, S.H. Clin. Rheumatol. (1984) [Pubmed]
  13. Inhibitory properties of triethylphosphine goldlupinylsulfide in adjuvant-induced arthritis in rats. Ghia, M., Mattioli, F., Novelli, F., Minganti, V. Farmaco (1995) [Pubmed]
  14. Induction of mammalian stress proteins by a triethylphosphine gold compound used in the therapy of rheumatoid arthritis. Caltabiano, M.M., Koestler, T.P., Poste, G., Greig, R.G. Biochem. Biophys. Res. Commun. (1986) [Pubmed]
  15. Reactions of triethylphosphine gold(I) complexes with heme proteins: novel spin-state changes in cytochrome b562, myoglobin, and hemoglobin. Grootveld, M.C., Otiko, G., Sadler, P.J., Cammack, R. J. Inorg. Biochem. (1986) [Pubmed]
  16. Adverse reactions with oral and parenteral gold preparations. Tozman, E.C., Gottlieb, N.L. Medical toxicology. (1987) [Pubmed]
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