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Chemical Compound Review

Cionin     3-[[(2S)-2-[[(2S)-2-[2- [[(2S)-2-[[(2S)-2...

Synonyms: AC1MJ00W, 126985-56-6, Asn-tyr(SO3)-tyr(SO3)-gly-trp-met-asp-phe-NH2
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Disease relevance of Cionin


High impact information on Cionin


Anatomical context of Cionin


Associations of Cionin with other chemical compounds


Gene context of Cionin


Analytical, diagnostic and therapeutic context of Cionin


  1. Cionin: a disulfotyrosyl hybrid of cholecystokinin and gastrin from the neural ganglion of the protochordate Ciona intestinalis. Johnsen, A.H., Rehfeld, J.F. J. Biol. Chem. (1990) [Pubmed]
  2. Phylogeny of the cholecystokinin/gastrin family. Johnsen, A.H. Frontiers in neuroendocrinology. (1998) [Pubmed]
  3. Molecular cloning of a putative Ciona intestinalis cionin receptor, a new member of the CCK/gastrin receptor family. Nilsson, I.B., Svensson, S.P., Monstein, H.J. Gene (2003) [Pubmed]
  4. cDNA deduced procionin. Structure and expression in protochordates resemble that of procholecystokinin in mammals. Monstein, H.J., Thorup, J.U., Folkesson, R., Johnsen, A.H., Rehfeld, J.F. FEBS Lett. (1993) [Pubmed]
  5. Genomic structure of the gene encoding cionin--a cholecystokinin/gastrin like peptide. Monstein, H.J. Neuroreport (1995) [Pubmed]
  6. Stimulation of rainbow trout gallbladder contraction by cionin, an ancestral member of the CCK/gastrin family. Schjoldager, B., Jørgensen, J.C., Johnsen, A.H. Gen. Comp. Endocrinol. (1995) [Pubmed]
  7. Stimulation by the ancestral member of the CCK/gastrin family, cionin, of trout gallbladder contraction. Johnsen, A.H., Schjoldager, B., Jørgensen, J. Ann. N. Y. Acad. Sci. (1994) [Pubmed]
  8. Solid-phase synthesis of cionin, a protochordate-derived octapeptide related to the gastrin/cholecystokinin family of peptides, and its mono-tyrosine-sulfate-containing derivatives. Kitagawa, K., Futaki, S., Yagami, T., Sumi, S., Inoue, K. Int. J. Pept. Protein Res. (1994) [Pubmed]
  9. Cholecystokinin and gastrin are not equally sensitive to GTP gamma S at CCKB receptors: importance of the sulphated tyrosine. Lallement, J.C., Oiry, C., Lima-Leite, A.C., Lignon, M.F., Fulcrand, P., Galleyrand, J.C., Martinez, J. Eur. J. Pharmacol. (1995) [Pubmed]
  10. Effect of cionin on histamine and acid secretion by the perfused rat stomach. Mårvik, R., Johnsen, A.H., Rehfeld, J.F., Sandvik, A., Waldum, H.L. Scand. J. Gastroenterol. (1994) [Pubmed]
  11. Cionin, a protochordean hybrid of cholecystokinin and gastrin: biological activity in mammalian systems. Schjoldager, B., Park, J., Johnsen, A.H., Yamada, T., Rehfeld, J.F. Am. J. Physiol. (1991) [Pubmed]
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