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Chemical Compound Review

Dibrom     1,2-dibromo-1,1-dichloro-2...

Synonyms: Nikabrom, fosforan, Dibromfos, Fosbrom, Trumpet, ...
 
 
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Disease relevance of Dibrom

 

High impact information on Dibrom

  • Brain-acetlycholinesterase inhibition in a marine teleost during lethal and sublethal exposures to 1,2-dibromo-2,2-dichloroethyl dimethyl phosphate (naled) in seawater [4].
  • A study was conducted to evaluate the impact of naled on honey bees as a result of their exposure to aerial ULV applications of this insecticide during three routine mosquito spray missions by Manatee County Mosquito Control District in Florida during the summer of 1999 [1].
  • We characterize two genes expressed in Acropora cervicornis upon exposure to 0.5 microg/l of dibrom, a pesticide used for mosquito control in the Florida Keys [5].
  • Characterizing stress gene expression in reef-building corals exposed to the mosquitoside dibrom [5].
  • Within the context of stressors examined, the D25 probe demonstrates toxicant and concentration specificity for organophosphates, whereas the D50 probe had broader specificity, detecting transcripts in corals exposed to dibrom, naphthalene, and temperature stress [5].
 

Chemical compound and disease context of Dibrom

  • 3. Regarding four organophosphate insecticides, the mechanism of inhibition in all cases was mixed (competitive and uncompetitive) and, based on inhibition constants, the order of toxicity was naled greater than paraoxon greater than trichlorfon greater than oxydemeton methyl [6].
 

Biological context of Dibrom

  • Decline of naled followed first order kinetics in all cases; consequently, half-life of naled under each treatment was determined from the slope of each line [7].
 

Associations of Dibrom with other chemical compounds

 

Analytical, diagnostic and therapeutic context of Dibrom

  • Naled deposits were collected on filter paper and subsequently analyzed by gas chromatography [1].
  • Efficiency of ground-applied naled (Dibrom 14), based on caged mosquito bioassays in a moderately vegetated coastal southeastern Florida citrus grove, proved to be significantly associated with downwind distance [10].

References

  1. Impact of naled on honey bee Apis mellifera L. survival and productivity: aerial ULV application using a flat-fan nozzle system. Zhong, H., Latham, M., Hester, P.G., Frommer, R.L., Brock, C. Arch. Environ. Contam. Toxicol. (2003) [Pubmed]
  2. Estimation of the LD1 and extrapolation of the LD0.1 for five organophosphate pesticides. Haley, T.J., Farmer, J.H., Harmon, J.R., Dooley, K.L. Arch. Toxicol. (1975) [Pubmed]
  3. Impact of naled on the mosquito vectors of eastern equine encephalitis virus. Moore, C.G. J. Am. Mosq. Control Assoc. (1998) [Pubmed]
  4. Brain-acetlycholinesterase inhibition in a marine teleost during lethal and sublethal exposures to 1,2-dibromo-2,2-dichloroethyl dimethyl phosphate (naled) in seawater. Coppage, D.L., Matthews, E. Toxicol. Appl. Pharmacol. (1975) [Pubmed]
  5. Characterizing stress gene expression in reef-building corals exposed to the mosquitoside dibrom. Morgan, M.B., Snell, T.W. Mar. Pollut. Bull. (2002) [Pubmed]
  6. The kinetics and inhibition of p-nitrophenylacetate-hydrolysing esterases in a solitary bee, Megachile rotundata (Fab.). Frohlich, D.R., Boeker, E.A., Brindley, W.A. Xenobiotica (1990) [Pubmed]
  7. Half-life of naled under three test scenarios. Tietze, N.S., Shaffer, K.R., Hester, P.G. J. Am. Mosq. Control Assoc. (1996) [Pubmed]
  8. Efficacy of Dibrom, Trumpet, and Scourge against four mosquito species in Louisiana. Ham, C.M., Meisch, M.V., Meek, C.L. J. Am. Mosq. Control Assoc. (1999) [Pubmed]
  9. Current status on the Florida Abate Monitoring program--susceptibility levels of three species of mosquitoes during 1984. Boike, A.H., Rathburn, C.B., Lang, K.L., Masters, H.M., Floore, T.G. J. Am. Mosq. Control Assoc. (1985) [Pubmed]
  10. Evaluation of equipment modifications and dosage rates of ground ULV applications of naled against Aedes taeniorhynchus in a Florida citrus grove. Curtis, G.A., Mason, J. J. Am. Mosq. Control Assoc. (1988) [Pubmed]
 
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