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Chemical Compound Review

arachidonic acid     (5Z,8Z,11Z,14Z)-icosa- 5,8,11,14-tetraenoic...

Synonyms: arachidonate, CHEMBL15594, AG-F-70356, BSPBio_001539, A3555_SIGMA, ...
 
 
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Disease relevance of arachidonic acid

 

High impact information on arachidonic acid

 

Anatomical context of arachidonic acid

 

Associations of arachidonic acid with other chemical compounds

  • CONCLUSION: We conclude that FAEEs in meconium, particularly ethyl linoleate and ethyl AA, are biomarkers of high specificity for prenatal exposure to alcohol in newborn infants [4].
  • Prostaglandin (PG) synthesis and degradation were examined in different regions (epithelial versus non-epithelial structures) of the rat distal colon by both HPLC analysis of [14C] arachidonate (AA) metabolites and by specific radioimmunoassays [6].

References

  1. The effects of beraprost Na, a stable prostacyclin analog, on animal models of stroke. Hirano, T., Yamori, Y., Kanai, N., Umetsu, T., Nishio, S. Mol. Chem. Neuropathol. (1992) [Pubmed]
  2. Role of protein kinase C in the regulation of prostaglandin synthesis in human endothelium. Garcia, J.G., Stasek, J., Natarajan, V., Patterson, C.E., Dominguez, J. Am. J. Respir. Cell Mol. Biol. (1992) [Pubmed]
  3. Differential changes of adrenoceptor- and muscarinic receptor-linked prostacyclin synthesis by the aorta and urinary bladder of the diabetic rat. Jeremy, J.Y., Thompson, C.S., Mikhailidis, D.P. Br. J. Pharmacol. (1993) [Pubmed]
  4. Fatty acid ethyl esters in meconium: are they biomarkers of fetal alcohol exposure and effect? Ostrea, E.M., Hernandez, J.D., Bielawski, D.M., Kan, J.M., Leonardo, G.M., Abela, M.B., Church, M.W., Hannigan, J.H., Janisse, J.J., Ager, J.W., Sokol, R.J. Alcohol. Clin. Exp. Res. (2006) [Pubmed]
  5. Effects of chroman derivatives on platelet aggregation induced by some aggregating agents in rabbits. Aida, Y., Kasama, T., Fukaya, H., Takeuchi, N., Sugiyama, K., Tobinaga, S. Clin. Exp. Pharmacol. Physiol. (1998) [Pubmed]
  6. Patterns of prostaglandin synthesis and degradation in isolated superficial and proliferative colonic epithelial cells compared to residual colon. Craven, P.A., DeRubertis, F.R. Prostaglandins (1983) [Pubmed]
  7. Transfomration of arachidonic acid into 12-hydroxy-5,8,10,14-eicosatetraenoic acid by mouse peritoneal macrophages. Rigaud, M., Durand, J., Breton, J.C. Biochim. Biophys. Acta (1979) [Pubmed]
 
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