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Chemical Compound Review

Trierucin     2,3-bis[[(Z)-docos-13- enoyl]oxy]propyl (Z)...

Synonyms: Trierucate, Lorenzo oil, Lorenzo's oil, Erucin, tri-, T9154_SIGMA, ...
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Disease relevance of Trierucate


High impact information on Trierucate


Anatomical context of Trierucate


  1. Follow-up of 89 asymptomatic patients with adrenoleukodystrophy treated with Lorenzo's oil. Moser, H.W., Raymond, G.V., Lu, S.E., Muenz, L.R., Moser, A.B., Xu, J., Jones, R.O., Loes, D.J., Melhem, E.R., Dubey, P., Bezman, L., Brereton, N.H., Odone, A. Arch. Neurol. (2005) [Pubmed]
  2. Enhanced lymphocyte proliferation in patients with adrenoleukodystrophy treated with erucic acid (22:1)-rich triglycerides. Pour, R.B., Stöckler-Ipsiroglu, S., Hunneman, D.H., Gahr, M., Korenke, G.C., Pabst, W., Hanefeld, F., Peters, A. J. Inherit. Metab. Dis. (2000) [Pubmed]
  3. Effect of different dietary triglycerides on 7alpha-hydroxylation of cholesterol and other mixed-function oxidations. Björkhem, I., Blomstrand, R., Svensson, L. J. Lipid Res. (1978) [Pubmed]
  4. Influence of dietary partially hydrogenated vegetable and marine oils on membrane composition and function of liver microsomes and platelets in the rat. Blomstrand, R., Diczfalusy, U., Sisfontes, L., Svensson, L. Lipids (1985) [Pubmed]
  5. Lipase in lipid bodies of cotyledons of rape and mustard seedlings. Lin, Y.H., Huang, A.H. Arch. Biochem. Biophys. (1983) [Pubmed]
  6. Intracellular lipase activities in heart and skeletal muscle homogenates. The absence of trierucin cleavage by the heart: a possible biochemical basis for erucic acid lipidosis. Mersel, M., Heller, M., Pinson, A. Biochim. Biophys. Acta (1979) [Pubmed]
  7. Brain, liver, and adipose tissue erucic and very long chain fatty acid levels in adrenoleukodystrophy patients treated with glyceryl trierucate and trioleate oils (Lorenzo's oil). Rasmussen, M., Moser, A.B., Borel, J., Khangoora, S., Moser, H.W. Neurochem. Res. (1994) [Pubmed]
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