Chemical Compound Review:
BuCast [(1S,6S,7S,8R,8aR)-1,7,8- trihydroxy-1,2,3...
Synonyms:
Celgosivir, B-CAST, VIR-222, SureCN135812, MBI-3253, ...
- 6-0-butanoylcastanospermine (MDL 28,574) inhibits glycoprotein processing and the growth of HIVs. Taylor, D.L., Sunkara, P.S., Liu, P.S., Kang, M.S., Bowlin, T.L., Tyms, A.S. AIDS (1991)
- The effect of oral treatment with 6-O-butanoyl castanospermine (MDL 28,574) in the murine zosteriform model of HSV-1 infection. Bridges, C.G., Ahmed, S.P., Kang, M.S., Nash, R.J., Porter, E.A., Tyms, A.S. Glycobiology (1995)
- Antiviral activity and metabolism of the castanospermine derivative MDL 28,574, in cells infected with herpes simplex virus type 2. Ahmed, S.P., Nash, R.J., Bridges, C.G., Taylor, D.L., Kang, M.S., Porter, E.A., Tyms, A.S. Biochem. Biophys. Res. Commun. (1995)
- The prevention of cell adhesion and the cell-to-cell spread of HIV-1 in vitro by the alpha-glucosidase 1 inhibitor, 6-O-butanoyl castanospermine (MDL 28574). Bridges, C.G., Brennan, T.M., Taylor, D.L., McPherson, M., Tyms, A.S. Antiviral Res. (1994)
- Action of celgosivir (6 O-butanoyl castanospermine) against the pestivirus BVDV: implications for the treatment of hepatitis C. Whitby, K., Taylor, D., Patel, D., Ahmed, P., Tyms, A.S. Antivir. Chem. Chemother. (2004)
- Inhibition of alpha-glucosidase I of the glycoprotein-processing enzymes by 6-O-butanoyl castanospermine (MDL 28,574) and its consequences in human immunodeficiency virus-infected T cells. Taylor, D.L., Kang, M.S., Brennan, T.M., Bridges, C.G., Sunkara, P.S., Tyms, A.S. Antimicrob. Agents Chemother. (1994)
- Inhibition of glycoprotein processing and HIV replication by castanospermine analogues. Sunkara, P.S., Kang, M.S., Bowlin, T.L., Liu, P.S., Tyms, A.S., Sjoerdsma, A. Ann. N. Y. Acad. Sci. (1990)