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Chemical Compound Review

AC1O3LQE     (3-amino-1-hydroxy-1- phosphono...

Synonyms: A831355
This record was replaced with 4674.
 
 
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Disease relevance of Aminomux

 

High impact information on Aminomux

 

Chemical compound and disease context of Aminomux

 

Biological context of Aminomux

 

Anatomical context of Aminomux

 

Associations of Aminomux with other chemical compounds

  • To evaluate dose proportionality and absolute bioavailability of a new enteric-coated pellet formulation of pamidronate disodium (AREDIA), nine females (aged 52-66 years) were given three different single peroral doses of pamidronate disodium (75, 150, and 300 mg) and an i.v. infusion of 15 mg over 30 minutes at constant infusion rate [9].
 

Gene context of Aminomux

 

Analytical, diagnostic and therapeutic context of Aminomux

References

  1. Efficacy of pamidronate in reducing skeletal complications in patients with breast cancer and lytic bone metastases. Protocol 19 Aredia Breast Cancer Study Group. Hortobagyi, G.N., Theriault, R.L., Porter, L., Blayney, D., Lipton, A., Sinoff, C., Wheeler, H., Simeone, J.F., Seaman, J., Knight, R.D. N. Engl. J. Med. (1996) [Pubmed]
  2. Comparative study of pamidronate disodium and etidronate disodium in the treatment of cancer-related hypercalcemia. Gucalp, R., Ritch, P., Wiernik, P.H., Sarma, P.R., Keller, A., Richman, S.P., Tauer, K., Neidhart, J., Mallette, L.E., Siegel, R. J. Clin. Oncol. (1992) [Pubmed]
  3. Combined analysis of two multicenter, randomized, placebo-controlled studies of pamidronate disodium for the palliation of bone pain in men with metastatic prostate cancer. Small, E.J., Smith, M.R., Seaman, J.J., Petrone, S., Kowalski, M.O. J. Clin. Oncol. (2003) [Pubmed]
  4. Pamidronate treatment of the neurologic sequelae of pagetic spinal stenosis. Wallace, E., Wong, J., Reid, I.R. Arch. Intern. Med. (1995) [Pubmed]
  5. Health-related quality of life among patients with breast cancer receiving zoledronic acid or pamidronate disodium for metastatic bone lesions. Weinfurt, K.P., Castel, L.D., Li, Y., Timbie, J.W., Glendenning, G.A., Schulman, K.A. Medical care. (2004) [Pubmed]
  6. Rapid, divergent changes in spinal and forearm bone density following short-term intravenous treatment of Paget's disease with pamidronate disodium. Price, R.I., Gutteridge, D.H., Stuckey, B.G., Kent, G.N., Retallack, R.W., Prince, R.L., Bhagat, C.I., Johnston, C.A., Nicholson, G.C., Stewart, G.O. J. Bone Miner. Res. (1993) [Pubmed]
  7. Circulating PTH and PTHrP levels before and after treatment of tumor induced hypercalcemia with Pamidronate Disodium (APD). Grill, V., Murray, R.M., Ho, P.W., Santamaria, J.D., Pitt, P., Potts, C., Jerums, G., Martin, T.J. J. Clin. Endocrinol. Metab. (1992) [Pubmed]
  8. Pharmacokinetics of pamidronate disodium in patients with cancer with normal or impaired renal function. Berenson, J.R., Rosen, L., Vescio, R., Lau, H.S., Woo, M., Sioufi, A., Kowalski, M.O., Knight, R.D., Seaman, J.J. Journal of clinical pharmacology. (1997) [Pubmed]
  9. Pharmacokinetic evaluation of pamidronate after oral administration: a study on dose proportionality, absolute bioavailability, and effect of repeated administration. Hyldstrup, L., Flesch, G., Hauffe, S.A. Calcif. Tissue Int. (1993) [Pubmed]
  10. A comparative study of samarium-153-ethylenediaminetetramethylene phosphonic acid with pamidronate disodium in the treatment of patients with painful metastatic bone cancer. Wang, R.F., Zhang, C.L., Zhu, S.L., Zhu, M. Medical principles and practice : international journal of the Kuwait University, Health Science Centre. (2003) [Pubmed]
  11. Pamidronate disodium and possible ocular adverse drug reactions. Macarol, V., Fraunfelder, F.T. Am. J. Ophthalmol. (1994) [Pubmed]
  12. The use of pamidronate for hypercalcemia secondary to acute vitamin D intoxication. Lee, D.C., Lee, G.Y. J. Toxicol. Clin. Toxicol. (1998) [Pubmed]
  13. Immobilization hypercalcemia treatment with pamidronate disodium after spinal cord injury. Massagli, T.L., Cardenas, D.D. Archives of physical medicine and rehabilitation. (1999) [Pubmed]
  14. Inhibition of cholesteatomatous bone resorption with pamidronate disodium. Yoon, T.H., Lee, S.H., Park, M.H., Chung, J.W., Kim, H.J. Acta Otolaryngol. (2001) [Pubmed]
  15. Intravenous pamidronate for hypercalcemia of primary hyperparathyroidism. Tal, A., Graves, L. South. Med. J. (1996) [Pubmed]
  16. Treatment of cancer-associated hypercalcemia. Double-blind comparison of rapid and slow intravenous infusion regimens of pamidronate disodium and saline alone. Gucalp, R., Theriault, R., Gill, I., Madajewicz, S., Chapman, R., Navari, R., Ahmann, F., Zelenakas, K., Heffernan, M., Knight, R.D. Arch. Intern. Med. (1994) [Pubmed]
  17. Determination of the bisphosphonate pamidronate disodium in urine by pre-column derivatization with fluorescamine, high-performance liquid chromatography and fluorescence detection. Flesch, G., Hauffe, S.A. J. Chromatogr. (1989) [Pubmed]
  18. Intravenous pamidronate disodium treatment of bone metastases in patients with breast cancer. A dose-seeking study. Glover, D., Lipton, A., Keller, A., Miller, A.A., Browning, S., Fram, R.J., George, S., Zelenakas, K., Macerata, R.S., Seaman, J.J. Cancer (1994) [Pubmed]
  19. Intravenous bisphosphonate prevents symptomatic osteoporotic vertebral collapse in patients after liver transplantation. Reeves, H.L., Francis, R.M., Manas, D.M., Hudson, M., Day, C.P. Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. (1998) [Pubmed]
  20. The use of zoledronic acid, a novel, highly potent bisphosphonate, for the treatment of hypercalcemia of malignancy. Major, P. Oncologist (2002) [Pubmed]
 
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