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Chemical Compound Review

Potassium-43     potassium

Synonyms: AC1O3TGF, 14903-02-7, 43K, Potassium, isotope of mass 43
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Disease relevance of potassium

  • To assess the validity of myocardial imaging with potassium-43 (43K) early after the onset of ischemia, the left anterior descending artery was occluded with a baloon tip catheter in 32 intact anesthetized dogs [1].
  • To evaluate the quantitative relationships between resting potassium-43 (43K) myocardial imaging and left ventricular segmental contraction abnormalities, 15 patients were studied by both radionuclide and contrast angiographic techniques at least two months following transmural myocardial infarction [2].
  • Thus, in this initial group of patients following transmural infarction, potassium-43 imaging can be accurately and quantitatively correlated with the site and extent of regional ventricular dysfunction as it is assessed by quantitative left ventricular angiography [2].
  • Evaluation of potassium-43 scintillation images during early myocardial ischemia in an animal model [1].
  • Noninvasive myocardial imaging with potassium-43 and rubidium-81 in patients with left bundle branch block [3].

High impact information on potassium


Chemical compound and disease context of potassium


Anatomical context of potassium

  • In the current study a non-invasive method was developed to measure skeletal muscle K+ before and after exercise, using an isotope of K+, potassium-43 (43K+) [7].
  • Sodium-77 bromide and indium-113m ethylenediaminetetracetic acid were used as extracellular fluid space markers, radioactive water as a total fluid space marker, and potassium-43 chloride to examine the existence of a bone membrane [8].

Analytical, diagnostic and therapeutic context of potassium

  • Noninvasive study of extremity perfusion by potassium 43 scanning [9].
  • RESULTS: Over time, the number of treatment group participants who had at least one serving from each food group (P <.01), and who had the recommended number of servings from each food group (P <.05), significantly increased in comparison to the control group [10].


  1. Evaluation of potassium-43 scintillation images during early myocardial ischemia in an animal model. Haider, B., Oldewurtel, H.A., Moschos, C.B., Regan, T.J. Circulation (1976) [Pubmed]
  2. Quantitative relationships between potassium-43 imaging and left ventricular cineangiography following myocardial infarction in man. Zaret, B.L., Vlay, S.C., Freedman, G.S., Wolfson, S., Cohen, L.S. Circulation (1975) [Pubmed]
  3. Noninvasive myocardial imaging with potassium-43 and rubidium-81 in patients with left bundle branch block. McGowan, R.L., Welch, T.G., Zaret, B.L., Bryson, A.L., Martin, N.D., Flamm, M.D. Am. J. Cardiol. (1976) [Pubmed]
  4. Impaired renal function in obstructive jaundice: enhanced glomerular thromboxane synthesis and effects of thromboxane receptor blockade in bile duct-ligated rats. Kramer, H.J., Schwarting, K., Bäcker, A. Clin. Sci. (1995) [Pubmed]
  5. Detection of coronary artery disease with rapid serial rescanning with potassium-43 at rest. Markov, A.K., Smith, R.O., Lehan, P.H., Galyean, J.R., Rodriguez, G., Hellems, H.K. Am. J. Cardiol. (1979) [Pubmed]
  6. The effect of a low dose versus a conventional dose of hydrochlorothiazide on ventricular fibrillation threshold and electrolyte levels in laboratory rats. Khedun, S.M., Maharaj, B., Naicker, T. Braz. J. Med. Biol. Res. (1996) [Pubmed]
  7. Potassium loss from skeletal muscle during exercise in man: a radioisotope study. Qayyum, M.S., Freemantle, C.A., Carey, C.J., Page, B.C., Soper, N., Paterson, D.J., Robbins, P.A. Exp. Physiol. (1993) [Pubmed]
  8. Isotopically labelled compounds in the study of extracellular fluid space in dog bone. Khan, R.A. Med. Biol. (1979) [Pubmed]
  9. Noninvasive study of extremity perfusion by potassium 43 scanning. Miyamoto, A.T., Mishkin, F.S., Maxwell, T.M. Archives of surgery (Chicago, Ill. : 1960) (1975) [Pubmed]
  10. Culturally relevant nutrition education improves dietary quality among WIC-eligible Vietnamese immigrants. Ikeda, J.P., Pham, L., Nguyen, K.P., Mitchell, R.A. Journal of nutrition education and behavior. (2002) [Pubmed]
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