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Chemical Compound Review

Deadmag     propan-2-yl (Z)-3-(ethylamino-methoxy...

Synonyms: Blotic, Tsar, Safrotin S 200, HSDB 6985, LS-1173, ...
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Disease relevance of PROPETAMPHOS

  • Five volunteers ingested a propetamphos dose of 10 micrograms kg-1 (35 nmol kg-1) body weight [1].
  • Plunge dipping in diazinon, propetamphos or flumethrin, or the use of synthetic pyrethroid pour-on preparations and an oral drench of ivermectin had little effect because ear mite infestations were detected in the flocks after these treatments [2].
  • Propetamphos pour-on formulation for the control of lice on sheep: effect of lice on weight gain and wool production [3].
  • The TIE programme indicated that the most likely toxic agents within the effluent were the organophosphate pesticides diazinon and to lesser extent propetamphos, although these did not account for all of the observed toxicity [4].

High impact information on PROPETAMPHOS


Biological context of PROPETAMPHOS


Associations of PROPETAMPHOS with other chemical compounds


Analytical, diagnostic and therapeutic context of PROPETAMPHOS


  1. Development of a urinary biomarker for exposure to the organophosphate propetamphos: data from an oral and dermal human volunteer study. Garfitt, S.J., Jones, K., Mason, H.J., Cocker, J. Biomarkers (2002) [Pubmed]
  2. Epidemiology of subclinical ovine psoroptic otoacariasis in Great Britain. Bates, P.G. Vet. Rec. (1996) [Pubmed]
  3. Propetamphos pour-on formulation for the control of lice on sheep: effect of lice on weight gain and wool production. Ormerod, V.J., Henderson, D. Res. Vet. Sci. (1986) [Pubmed]
  4. Toxicity reduction evaluation, toxicity identification evaluation and toxicity tracking in direct toxicity assessment. Hutchings, M., Johnson, I., Hayes, E., Girling, A.E., Thain, J., Thomas, K., Benstead, R., Whale, G., Wordon, J., Maddox, R., Chown, P. Ecotoxicology (2004) [Pubmed]
  5. Toxicology and fate of Pestanal and commercial propetamphos formulations in river and estuarine sediment. García-Ortega, S., Holliman, P.J., Jones, D.L. Sci. Total Environ. (2006) [Pubmed]
  6. Determination of solid-liquid partition coefficients (K(d)) for diazinon, propetamphos and cis-permethrin: implications for sheep dip disposal. Cooke, C.M., Shaw, G., Lester, J.N., Collins, C.D. Sci. Total Environ. (2004) [Pubmed]
  7. Oral and dermal exposure to propetamphos: a human volunteer study. Garfitt, S.J., Jones, K., Mason, H.J., Cocker, J. Toxicol. Lett. (2002) [Pubmed]
  8. Resistance to two organophosphorus insecticides in New Zealand populations of the Australian sheep blowfly, Lucilia cuprina. Wilson, J.A., Heath, A.C. Med. Vet. Entomol. (1994) [Pubmed]
  9. Survey of levels of propetamphos and diazinon used to control sheep scab in Northern Ireland. Blanchflower, W.J., McCracken, R.J., Rice, D.A., Clements, A. Vet. Rec. (1990) [Pubmed]
  10. Determination of residues of pyrethroid and organophosphorous ectoparasiticides in foods of animal origin. Túri, M.S., Soós, K., Végh, E. Acta Vet. Hung. (2000) [Pubmed]
  11. Pharmacokinetics of propetamphos following intravenous administration in the F344 rat. Dix, K., Burka, L.T., Dauterman, W.C. J. Biochem. Toxicol. (1992) [Pubmed]
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