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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Chemical Compound Review

Isobutanal     2-methylpropanal

Synonyms: Isobutyral, Isobutaldehyde, Methylpropanal, AGN-PC-00B8LT, CPD-7000, ...
 
 
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Disease relevance of NSC 6739

 

High impact information on NSC 6739

 

Biological context of NSC 6739

 

Anatomical context of NSC 6739

  • The addition of a precursor of the enol form of isobutanal to neutrophils results in formation of triplet acetone, as attested to by emission from appropriate acceptors and cell damage (Nascimento et al., 1986 Biochim. Biophys. Acta 888, 337-342) [11].
 

Associations of NSC 6739 with other chemical compounds

References

  1. Damages induced in lambda phage DNA by enzyme-generated triplet acetone. Menck, C.F., Cabral-Neto, J.B., Faljoni-Alário, A., Alcantara-Gomes, R. Mutat. Res. (1986) [Pubmed]
  2. Sensory detection of glutaraldehyde in drinking water-emergence of sensitivity and specific anosmia. Cain, W.S., Schmidt, R. Chem. Senses (2002) [Pubmed]
  3. Transient state kinetics of the reactions of isobutyraldehyde with compounds I and II of horseradish peroxidase. Bohne, C., MacDonald, I.D., Dunford, H.B. J. Biol. Chem. (1987) [Pubmed]
  4. Enzyme-generated electronically excited carbonyl compounds, Acetone phosphorescence during the peroxidase-catalyzed aerobic oxidation of isobutanal. Oliveira, O.M., Haun, M., Durán, N., O'Brien, P.J., O'Brien, C.R., Bechara, E.J., Cilento, G. J. Biol. Chem. (1978) [Pubmed]
  5. Efficient total synthesis of pulchellalactam, a CD45 protein tyrosine phosphatase inhibitor. Li, W.R., Lin, S.T., Hsu, N.M., Chern, M.S. J. Org. Chem. (2002) [Pubmed]
  6. Chemiluminescent aldehyde and beta-diketone reactions promoted by peroxynitrite. Knudsen, F.S., Penatti, C.A., Royer, L.O., Bidart, K.A., Christoff, M., Ouchi, D., Bechara, E.J. Chem. Res. Toxicol. (2000) [Pubmed]
  7. Isobutyraldehyde administered by inhalation (whole body exposure) for up to thirteen weeks or two years was a respiratory tract toxicant but was not carcinogenic in F344/N rats and B6C3F1 mice. Abdo, K.M., Haseman, J.K., Nyska, A. Toxicol. Sci. (1998) [Pubmed]
  8. Does the photochemical conversion of colchicine into lumicolchicines involve triplet transients? A solvent dependence study. Nery, A.L., Quina, F.H., Moreira Jr, P.F., Medeiros, C.E., Baader, W.J., Shimizu, K., Catalani, L.H., Bechara, E.J. Photochem. Photobiol. (2001) [Pubmed]
  9. Enzymatic generation of triplet acetone by deglycosylated horseradish peroxidase. Silva, E., Edwards, A.M., Faljoni-Alario, A. Arch. Biochem. Biophys. (1990) [Pubmed]
  10. DNA damage during the peroxidase-catalyzed aerobic oxidation of isobutanal. Meneghini, R., Hoffmann, M.E., Durán, N., Faljoni, A., Cilento, G. Biochim. Biophys. Acta (1978) [Pubmed]
  11. Effects induced in neutrophils by a precursor of triplet acetone. Escobar, J.A., Cilento, G., Nascimento, A.L. Photochem. Photobiol. (1990) [Pubmed]
  12. Effects of wood and cotton smoke on the surface properties of pulmonary surfactant. Nieman, G.F., Clark, W.R. Respiration physiology. (1994) [Pubmed]
  13. The peroxidase/oxidase activity of soybean lipoxygenase--I. Triplet excited carbonyls from the reaction with isobutanal and the effect of glutathione. Schulte-Herbrüggen, T., Sies, H. Photochem. Photobiol. (1989) [Pubmed]
  14. Production of volatile compounds by Rhizopus oligosporus during soybean and barley tempeh fermentation. Mei Feng, X., Ostenfeld Larsen, T., Schn??rer, J. Int. J. Food Microbiol. (2007) [Pubmed]
  15. Degradation of isobutyraldehyde and its intermediates in a compost biofilter. Sercu, B., Baillieul, H., Demeestere, K., Van Langenhove, H., Verstraete, W. Communications in agricultural and applied biological sciences. (2003) [Pubmed]
 
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