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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Surface Properties

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Disease relevance of Surface Properties


High impact information on Surface Properties


Chemical compound and disease context of Surface Properties


Biological context of Surface Properties


Anatomical context of Surface Properties


Associations of Surface Properties with chemical compounds

  • In these studies, high levels of 111In-nitrilotriacetic acid complex are contained in unilamellar vesicles consisting of distearoyl phosphatidylcholine, cholesterol, and small amounts of other lipids which modify the surface properties [26].
  • Loss of cell surface sialic acids may result in a slight increase in agglutinability, but some other mechanism(s) is likely to be involved in alteration of surface properties that lead to marked agglutinability of the human uterine cervical cells obtained from cancer precursor lesions [27].
  • Partitioning of cells in dextran-poly(ethylene glycol) aqueous-aqueous two-phase systems is a sensitive method for separating cells and for obtaining information on their surface properties [28].
  • These results indicated that core replacement modulates the surface properties of the emulsion particles through the redistribution of cholesterol in the surface layers [29].
  • The aqueous two-phase partitioning analysis revealed a significant change in surface properties of GR following urea treatment; the observed partition coefficient values (cpm upper phase/bottom phase) were 0.022, 0.208, and 0.60 for GRc, GRc + 23 degrees C, and GRc + 2.5 M urea, respectively [30].

Gene context of Surface Properties

  • However, it seems likely that some of the diverse manifestations of this genetic disorder result from the ability of TSP2 to modulate the cell surface properties of mesenchymal cells, and thus, to affect cell functions such as adhesion and migration [31].
  • In addition, Aqy1p and Aqy2p can affect cell surface properties and may provide an advantage by dispersing the cells during starvation or during sexual reproduction [32].
  • We propose that although Pax3 function is related to cell surface properties, its role may differ in various tissues [23].
  • We suggest that the primary role of Pax6 is the continual regulation of cell surface properties responsible for both cellular identity and radial migration, defects of which cause regional cell sorting and abnormalities of migration in chimeras [33].
  • The three surfactant proteins SP-A, SP-B, and SP-C contribute to dynamic surface properties involved during respiration [34].

Analytical, diagnostic and therapeutic context of Surface Properties


  1. Partial characterization of proteoglycans isolated from neoplastic and nonneoplastic human breast tissues. Alini, M., Losa, G.A. Cancer Res. (1991) [Pubmed]
  2. Properties of acidic saccharides produced by B16 melanoma cells treated with 1-methyl-3-isobutylxanthine. Banks, J., Kreider, J.W., Sato, C., Davidson, E.A. Cancer Res. (1975) [Pubmed]
  3. Influence of growth media on Escherichia coli cell composition and ceftazidime susceptibility. Malouin, F., Chamberland, S., Brochu, N., Parr, T.R. Antimicrob. Agents Chemother. (1991) [Pubmed]
  4. Surface properties of Streptococcus sanguis FW213 mutants nonadherent to saliva-coated hydroxyapatite. Fives-Taylor, P.M., Thompson, D.W. Infect. Immun. (1985) [Pubmed]
  5. Cell surface hydrophobicity of pigmented and nonpigmented clinical Serratia marcescens strains. Rosenberg, M., Blumberger, Y., Judes, H., Bar-Ness, R., Rubinstein, E., Mazor, Y. Infect. Immun. (1986) [Pubmed]
  6. Surface functions during Mitosis I: phagocytosis, pinocytosis and mobility of surface-bound Con A. Berlin, R.D., Oliver, J.M., Walter, R.J. Cell (1978) [Pubmed]
  7. Membrane-bound lactoferrin alters the surface properties of polymorphonuclear leukocytes. Boxer, L.A., Haak, R.A., Yang, H.H., Wolach, J.B., Whitcomb, J.A., Butterick, C.J., Baehner, R.L. J. Clin. Invest. (1982) [Pubmed]
  8. The effects of aspirin on gastric mucosal integrity, surface hydrophobicity, and prostaglandin metabolism in cyclooxygenase knockout mice. Darling, R.L., Romero, J.J., Dial, E.J., Akunda, J.K., Langenbach, R., Lichtenberger, L.M. Gastroenterology (2004) [Pubmed]
  9. Adherence of bacteria to the intestine in sporadic cases of enteropathogenic Escherichia coli-associated diarrhea in infants and young children: a prospective study. Sherman, P., Drumm, B., Karmali, M., Cutz, E. Gastroenterology (1989) [Pubmed]
  10. Structural and functional analysis of Nup133 domains reveals modular building blocks of the nuclear pore complex. Berke, I.C., Boehmer, T., Blobel, G., Schwartz, T.U. J. Cell Biol. (2004) [Pubmed]
  11. Effect of fructose and other carbohydrates on the surface properties, lipoteichoic acid production, and extracellular proteins of Streptococcus mutans Ingbritt grown in continuous culture. Hardy, L., Jacques, N.A., Forester, H., Campbell, L.K., Knox, K.W., Wicken, A.J. Infect. Immun. (1981) [Pubmed]
  12. Effect of iron on surface charge and hydrophobicity of Neisseria gonorrhoeae. Magnusson, K.E., Kihlstrom, E., Norqvist, A., Davies, J., Normark, S. Infect. Immun. (1979) [Pubmed]
  13. Role of the rfaG and rfaP genes in determining the lipopolysaccharide core structure and cell surface properties of Escherichia coli K-12. Parker, C.T., Kloser, A.W., Schnaitman, C.A., Stein, M.A., Gottesman, S., Gibson, B.W. J. Bacteriol. (1992) [Pubmed]
  14. Protein inhibitors of crystal growth. Kaiser, E.T., Bock, S.C. J. Urol. (1989) [Pubmed]
  15. A second quorum-sensing system regulates cell surface properties but not phenazine antibiotic production in Pseudomonas aureofaciens. Zhang, Z., Pierson, L.S. Appl. Environ. Microbiol. (2001) [Pubmed]
  16. Changes in surface properties of normal and transformed cells caused by tunicamycin, an inhibitor of protein glycosylation. Duksin, D., Bornstein, P. Proc. Natl. Acad. Sci. U.S.A. (1977) [Pubmed]
  17. Phygocytosis by rabbit polymorphonuclear leukocytes: the effect of albumin and polyamino acids on latex uptake. Deierkauf, F.A., Beukers, H., Deierkauf, M., Riemersma, J.C. J. Cell. Physiol. (1977) [Pubmed]
  18. Selective reduction of phosphatidylglycerol and phosphatidylcholine in pulmonary surfactant by 4-aminopyrazolo(3,4d)pyrimidine in the rat. Suzuki, Y., Tabata, R. J. Lipid Res. (1980) [Pubmed]
  19. Inactivation of ompX causes increased interactions of type 1 fimbriated Escherichia coli with abiotic surfaces. Otto, K., Hermansson, M. J. Bacteriol. (2004) [Pubmed]
  20. Effect of direct electric current on the cell surface properties of phenol-degrading bacteria. Luo, Q., Wang, H., Zhang, X., Qian, Y. Appl. Environ. Microbiol. (2005) [Pubmed]
  21. Effects of glutathione-oxidizing agents on microtubule assembly and microtubule-dependent surface properties of human neutrophils. Oliver, J.M., Albertini, D.F., Berlin, R.D. J. Cell Biol. (1976) [Pubmed]
  22. Complement C3 participation in monocyte adhesion to different surfaces. McNally, A.K., Anderson, J.M. Proc. Natl. Acad. Sci. U.S.A. (1994) [Pubmed]
  23. Pax3 acts cell autonomously in the neural tube and somites by controlling cell surface properties. Mansouri, A., Pla, P., Larue, L., Gruss, P. Development (2001) [Pubmed]
  24. Studies on the surface properties of hybrid cells. III. A membrane glycoprotein found on the surface of a wide range of malignant cells. Atkinson, M.A., Bramwell, M.E. J. Cell. Sci. (1981) [Pubmed]
  25. Partitioning of erythrocytes from spontaneously hypertensive and Wistar-Kyoto rats. Walter, H., Levin, E.R., Krob, E.J., Mills, S.D. Hypertension (1986) [Pubmed]
  26. Stability of lipid vesicles in tissues of the mouse: a gamma-ray perturbed angular correlation study. Mauk, M.R., Gamble, R.C. Proc. Natl. Acad. Sci. U.S.A. (1979) [Pubmed]
  27. Different agglutinability of fibroblasts underlying various precursor lesions of human uterine cervical carcinoma. Chaudhuri, S., Koprowska, I., Rowinski, J. Cancer Res. (1975) [Pubmed]
  28. Subfractionation of human peripheral blood lymphocytes on the basis of their surface properties by partitioning in two-polymer aqueous phase systems. Walter, H., Webber, T.J., Michalski, J.P., McCombs, C.C., Moncla, B.J., Krob, E.J., Graham, L.L. J. Immunol. (1979) [Pubmed]
  29. Physical states of surface and core lipids in lipid emulsions and apolipoprotein binding to the emulsion surface. Saito, H., Minamida, T., Arimoto, I., Handa, T., Miyajima, K. J. Biol. Chem. (1996) [Pubmed]
  30. In vitro modulation of rat liver glucocorticoid receptor by urea. Moudgil, V.K., Vandenheede, L., Hurd, C., Eliezer, N., Lombardo, G. J. Biol. Chem. (1987) [Pubmed]
  31. Mice that lack thrombospondin 2 display connective tissue abnormalities that are associated with disordered collagen fibrillogenesis, an increased vascular density, and a bleeding diathesis. Kyriakides, T.R., Zhu, Y.H., Smith, L.T., Bain, S.D., Yang, Z., Lin, M.T., Danielson, K.G., Iozzo, R.V., LaMarca, M., McKinney, C.E., Ginns, E.I., Bornstein, P. J. Cell Biol. (1998) [Pubmed]
  32. Aquaporins in Saccharomyces: Characterization of a second functional water channel protein. Carbrey, J.M., Bonhivers, M., Boeke, J.D., Agre, P. Proc. Natl. Acad. Sci. U.S.A. (2001) [Pubmed]
  33. Pax6 regulates regional development and neuronal migration in the cerebral cortex. Talamillo, A., Quinn, J.C., Collinson, J.M., Caric, D., Price, D.J., West, J.D., Hill, R.E. Dev. Biol. (2003) [Pubmed]
  34. cDNA cloning of ovine pulmonary SP-A, SP-B, and SP-C: isolation of two different sequences for SP-B. Pietschmann, S.M., Pison, U. Am. J. Physiol. Lung Cell Mol. Physiol. (2000) [Pubmed]
  35. On the surface modification of microchannels for microcapillary electrophoresis chips. Lee, G.B., Lin, C.H., Lee, K.H., Lin, Y.F. Electrophoresis (2005) [Pubmed]
  36. Fractionation of microsomal membranes on the basis of their surface properties. Ohlsson, R., Jergil, B., Walter, H. Biochem. J. (1978) [Pubmed]
  37. Hydrogel microspheres: influence of chemical composition on surface morphology, local elastic properties, and bulk mechanical characteristics. Lekka, M., Sainz-Serp, D., Kulik, A.J., Wandrey, C. Langmuir : the ACS journal of surfaces and colloids. (2004) [Pubmed]
  38. Effect of emulsifiers on surface properties of sucrose by inverse gas chromatography. Rousset, P., Sellappan, P., Daoud, P. Journal of chromatography. A. (2002) [Pubmed]
  39. Analysis of plasma protein adsorption on polymeric nanoparticles with different surface characteristics. Lück, M., Paulke, B.R., Schröder, W., Blunk, T., Müller, R.H. J. Biomed. Mater. Res. (1998) [Pubmed]
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