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Chemical Compound Review

p,p'-Biphenol     4-(4-hydroxyphenyl)phenol

Synonyms: p,p'-Diphenol, PubChem8927, CHEMBL76398, SureCN15632, NSC-8711, ...
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Disease relevance of ASM DOD


High impact information on ASM DOD


Biological context of ASM DOD

  • Charge recombination (CR) kinetics following photoinduced charge transfer are measured by optical transient absorption for complexes of dimethyl viologen and diheptyl viologen with 4,4'-biphenol (MVBP and HVBP) in methanol [6].
  • However, enzymic hydrolysis of DNA releases the bound polymers. p,p'-Biphenol, however, did not bind to DNA following peroxidase-catalysed oxidation, but o,o'-biphenol readily binds to DNA following peroxidase-catalysed oxidation [7].

Anatomical context of ASM DOD


Associations of ASM DOD with other chemical compounds


Gene context of ASM DOD


  1. Inhibition of melanogenic activity by 4,4'-dihydroxybiphenyl in melanoma cells. No, J.K., Kim, Y.J., Lee, J.S., Chung, H.Y. Biol. Pharm. Bull. (2006) [Pubmed]
  2. Sister chromatid exchange induction in human lymphocytes exposed to benzene and its metabolites in vitro. Erexson, G.L., Wilmer, J.L., Kligerman, A.D. Cancer Res. (1985) [Pubmed]
  3. Ultrafast electron-transfer and solvent adiabaticity effects in viologen charge-transfer complexes. Ponnu, A., Sung, J., Spears, K.G. The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment & general theory (2006) [Pubmed]
  4. Lignan compounds and 4,4'-dihydroxybiphenyl protect C2C12 cells against damage from oxidative stress. Yoshikawa, A., Saito, Y., Maruyama, K. Biochem. Biophys. Res. Commun. (2006) [Pubmed]
  5. Metabolism and cytotoxicity of bisphenol A and other bisphenols in isolated rat hepatocytes. Nakagawa, Y., Tayama, S. Arch. Toxicol. (2000) [Pubmed]
  6. Solvent adiabaticity effects on ultrafast electron transfer in viologen charge transfer complexes. Moran, A.M., Aravindan, P., Spears, K.G. The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment & general theory. (2005) [Pubmed]
  7. Phenol oxidation product(s), formed by a peroxidase reaction, that bind to DNA. Subrahmanyam, V.V., O'Brien, P.J. Xenobiotica (1985) [Pubmed]
  8. Peroxidase/hydrogen peroxide--or bone marrow homogenate/hydrogen peroxide--mediated activation of phenol and binding to protein. Subrahmanyam, V.V., McGirr, L.G., O'Brien, P.J. Xenobiotica (1990) [Pubmed]
  9. Peroxidase-catalyzed-3-(glutathion-S-yl)-p,p'-biphenol formation. McGirr, L.G., Subrahmanyam, V.V., Moore, G.A., O'Brien, P.J. Chem. Biol. Interact. (1986) [Pubmed]
  10. Constituents of Agaricus xanthodermus Genevier: the first naturally endogenous azo compound and toxic phenolic metabolites. Gill, M., Strauch, R.J. Z. Naturforsch., C, Biosci. (1984) [Pubmed]
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