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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

CETAC     hexadecyl-trimethyl-azanium chloride

Synonyms: CTAC, HTAC, HDTMA-Cl, Dehyquart A, Aliquat 6, ...
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Disease relevance of Trimethylhexadecylammonium

  • After a 30 min loading period the release of CTAC in water was followed by simultaneously measuring both the antimicrobial activity of the coating's surface against Staphylococcus aureus and the release of the structurally related dye Rhodamine B [1].

High impact information on Trimethylhexadecylammonium

  • The effective mobility of iodide was decreased by the addition of 10 mM cetyltrimethylammonium chloride (CTAC) to an artificial seawater background electrolyte (BGE) so that transient ITP functioned and iodide was separated from other coexisting anions such as bromide, nitrite, and nitrate in seawater samples [2].
  • Recombinant pig growth hormone (rPGH) was solubilized from inclusion bodies by using the cationic surfactant cetyltrimethylammonium chloride (CTAC) [3].
  • CTAC PAGE employs KOH/CH(3)CO(2)H (pH 4-5.4) as a buffer system, K(+) as the leading ion and 3-aminopropionic acid as a trailing ion [4].
  • The interaction of surfactants sodium dodecyl sulfate (SDS), cetyl trimethyl ammonium chloride (CTAC) and lauryl alcohol ethoxylated (12 mol ethylene oxide) (LAE-12OE) was evaluated on the stratum corneum (SC) of shed snake skins from Bothrops jararaca, used as model membrane, and thermal characterized by differential scanning calorimetry (DSC) [5].
  • The SC model membranes treated with CTAC have had an augment of water content (except for whole SC treated for 8h) indicated by the expansion of the band 3600-3300 cm(-1), mainly for the tape-stripped samples after 12h treatment [6].

Chemical compound and disease context of Trimethylhexadecylammonium


Associations of Trimethylhexadecylammonium with other chemical compounds


Gene context of Trimethylhexadecylammonium

  • Cetyltrimethylammonium chloride (CTAC) was employed as the cationic surfactant micelle, its addition leading to EOF reversal [9].

Analytical, diagnostic and therapeutic context of Trimethylhexadecylammonium


  1. Amphiphilic conetworks as regenerative controlled releasing antimicrobial coatings. Tiller, J.C., Sprich, C., Hartmann, L. Journal of controlled release : official journal of the Controlled Release Society. (2005) [Pubmed]
  2. Capillary zone electrophoretic determination of iodide in seawater using transient isotachophoresis with artificial seawater as the background electrolyte. Yokota, K., Fukushi, K., Ishio, N., Sasayama, N., Nakayama, Y., Takeda, S., Wakida, S. Electrophoresis (2003) [Pubmed]
  3. Solubilization of growth hormone and other recombinant proteins from Escherichia coli inclusion bodies by using a cationic surfactant. Puri, N.K., Crivelli, E., Cardamone, M., Fiddes, R., Bertolini, J., Ninham, B., Brandon, M.R. Biochem. J. (1992) [Pubmed]
  4. Development of a non-denaturing electrophoresis system for characterization of neutralizing epitopes on HPV virus-like particles. Studentsov, Y.Y., Burk, R.D. J. Virol. Methods (2007) [Pubmed]
  5. Evaluation of the interaction of surfactants with stratum corneum model membrane from Bothrops jararaca by DSC. Baby, A.R., Lacerda, A.C., Velasco, M.V., Lopes, P.S., Kawano, Y., Kaneko, T.M. International journal of pharmaceutics. (2006) [Pubmed]
  6. Spectroscopic studies of stratum corneum model membrane from Bothrops jararaca treated with cationic surfactant. Baby, A.R., Lacerda, A.C., Velasco, M.V., Lopes, P.S., Kawano, Y., Kaneko, T.M. Colloids and surfaces. B, Biointerfaces. (2006) [Pubmed]
  7. Fluorescence dynamics of staphylococcal nuclease in aqueous solution and reversed micelles. Visser, A.J., van Engelen, J., Visser, N.V., van Hoek, A., Hilhorst, R., Freedman, R.B. Biochim. Biophys. Acta (1994) [Pubmed]
  8. Cellular uptake of hematoporphyrin derivative in KK-47 bladder cancer cells. Hisazumi, H., Miyoshi, N., Ueki, O., Nishino, A., Nakajima, K. Urol. Res. (1984) [Pubmed]
  9. Metal complex separation with on-line sample preconcentration in micellar electrokinetic chromatography. Isoo, K., Terabe, S. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. (2005) [Pubmed]
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