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Chemical Compound Review

DIMETHYLHEXANE     2-methylheptane

Synonyms: ACMC-1AVKM, M47949_ALDRICH, AG-E-84069, AG-F-86869, AG-G-10766, ...
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Disease relevance of NSC 24844


Psychiatry related information on NSC 24844

  • It is observed that the reaction time strongly affects column efficiency, while the proportion of isooctane in porogen influences peak symmetry of some solutes seriously [5].

High impact information on NSC 24844


Chemical compound and disease context of NSC 24844


Biological context of NSC 24844

  • alpha-Chymotrypsin (CT), spin-labeled at the active site by using an acylating label which constitutes a substrate for this protein, has been investigated in reverse micelles formed by AOT in isooctane [12].
  • A lipase-catalyzed enantioselective hydrolysis process under conditions of continuous in situ racemization of substrate with trioctylamine as the catalyst was developed for the production of (S)-suprofen from (R,S)-suprofen 2,2,2-trifluoroethyl thioester in isooctane [13].
  • Bovine heart submitochondrial particles (SMP) were solubilized in an asolectin isooctane reverse micellar system and the functionality of the respiratory chain was tested by spectroscopic and amperometric techniques [14].
  • Partially purified delta 5-3-ketosteroid isomerase (KSI) from Pseudomonas testosteroni was studied kinetically after solubilization in reverse micelles of aerosol OT (AOT) in isooctane and water, as regards its application to biotechnology [1].
  • The best conditions for GOX extraction were ensured using isooctane as solvent and hexanol and butanol as co-solvents at 76/6/18 volume ratio, pH 6.0, 0.2 M cetyl trimethylammonium bromide (CTAB) as cationic surfactant, and electrical conductivity (kappa) of 4.8 mS cm-1 [15].

Anatomical context of NSC 24844


Associations of NSC 24844 with other chemical compounds


Gene context of NSC 24844

  • The reversed micellar extraction (AOT/isooctane system) using the phase transfer method was investigated in relation to the AOT concentration and the water solubilization for ribonuclease A, lysozyme and cytochrome c. The minimal AOT concentration required for 100% forward extraction was obtained for these proteins [25].
  • The lipid requirements for insertion of the proteolipid were studied, therefore, after delipidation by several precipitations with isooctane, a nondenaturing solvent [26].
  • The final residue, obtained in about 50 min, was dissolved in isooctane and analysed by gas chromatography with an electron capture detector (GC/ECD) [27].
  • The dissociation of the tetrameric malic enzyme to monomers was favored by approximately 16 kJ/mol in AOT/isooctane reverse micelles versus aqueous media [28].
  • The kinetic analysis in water-saturated isooctane indicated that both acyl donor and acyl acceptor have profound influences on the lipase activity, E-value, and enantioselectivity [29].

Analytical, diagnostic and therapeutic context of NSC 24844


  1. Kinetics and stability of delta 5-3-ketosteroid isomerase from Pseudomonas testosteroni in the system of reverse micelles of aerosol OT in isooctane. Levashov, A.V., Khettal, B., de Lauzon, S., Waks, M., Cittanova, N. Biochimie (1992) [Pubmed]
  2. Degradation of isooctane by Mycobacterium austroafricanum IFP 2173: growth and catabolic pathway. Solano-Serena, F., Marchal, R., Heiss, S., Vandecasteele, J.P. J. Appl. Microbiol. (2004) [Pubmed]
  3. Nature of photochemical reactions in chromatophores of Chromatium D. III. Heterogeneity of the photosynthetic units. Takamiya, K.I., Nishimura, M. Biochim. Biophys. Acta (1975) [Pubmed]
  4. Kinetics and stability of a Chromobacterium viscosum lipase in reversed micellar and aqueous media. Prazeres, D.M., Garcia, F.A., Cabral, J.M. Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986) (1992) [Pubmed]
  5. Optimized preparation of poly(styrene-co- divinylbenzene-co-methacrylic acid) monolithic capillary column for capillary electrochromatography. Jin, W., Fu, H., Huang, X., Xiao, H., Zou, H. Electrophoresis (2003) [Pubmed]
  6. Inhibition of electron transfer by 3-alkyl-2-hydroxy-1,4-naphthoquinones in the ubiquinol-cytochrome c oxidoreductases of Rhodopseudomonas sphaeroides and mammalian mitochondria. Interaction with a ubiquinone-binding site and the Rieske iron-sulfur cluster. Matsuura, K., Bowyer, J.R., Ohnishi, T., Dutton, P.L. J. Biol. Chem. (1983) [Pubmed]
  7. Micellar solubilization of biopolymers in organic solvents. Activity and conformation of lysozyme in isooctane reverse micelles. Grandi, C., Smith, R.E., Luisi, P.L. J. Biol. Chem. (1981) [Pubmed]
  8. Microheterogeneous solvation for aminolysis reactions in AOT-based water-in-oil microemulsions. García-Río, L., Mejuto, J.C., Pérez-Lorenzo, M. Chemistry (Weinheim an der Bergstrasse, Germany) (2005) [Pubmed]
  9. Hydration and protein folding in water and in reverse micelles: compressibility and volume changes. Valdez, D., Le Huérou, J.Y., Gindre, M., Urbach, W., Waks, M. Biophys. J. (2001) [Pubmed]
  10. Reversible thermal unfolding of ribonuclease T1 in reverse micelles. Shastry, M.C., Eftink, M.R. Biochemistry (1996) [Pubmed]
  11. Enantioselective recognition mechanism of secondary alcohol by surfactant-coated lipases in nonaqueous media. Kamiya, N., Kasagi, H., Inoue, M., Kusunoki, K., Goto, M. Biotechnol. Bioeng. (1999) [Pubmed]
  12. Activity and conformational changes of alpha-chymotrypsin in reverse micelles studied by spin labeling. Marzola, P., Forte, C., Pinzino, C., Veracini, C.A. FEBS Lett. (1991) [Pubmed]
  13. Dynamic kinetic resolution of suprofen thioester via coupled trioctylamine and lipase catalysis. Lin, C.N., Tsai, S.W. Biotechnol. Bioeng. (2000) [Pubmed]
  14. Respiratory electron transfer activity in an asolectin-isooctane reverse micellar system. Escobar, L., Escamilla, E. Biochimie (1992) [Pubmed]
  15. Liquid-liquid extraction of commercial glucose oxidase by reversed micelles. Ferreira, L.F., Taqueda, M.E., Vitolo, M., Converti, A., Pessoa, A. J. Biotechnol. (2005) [Pubmed]
  16. Isolation and characterization of methanophenazine and function of phenazines in membrane-bound electron transport of Methanosarcina mazei Gö1. Abken, H.J., Tietze, M., Brodersen, J., Bäumer, S., Beifuss, U., Deppenmeier, U. J. Bacteriol. (1998) [Pubmed]
  17. Solubilization of ribosomes in reverse micelles. Palazzo, G., Luisi, P.L. Biochem. Biophys. Res. Commun. (1992) [Pubmed]
  18. Screening for candidate genes involved in tolerance to organic solvents in yeast. Matsui, K., Hirayama, T., Kuroda, K., Shirahige, K., Ashikari, T., Ueda, M. Appl. Microbiol. Biotechnol. (2006) [Pubmed]
  19. Fluorescence study of melanocyte stimulating hormones in AOT reverse micelles. Bhattacharyya, K., Basak, S. Biophys. Chem. (1993) [Pubmed]
  20. Important parameters affecting efficiency of protein refolding by reversed micelles. Goto, M., Hashimoto, Y., Fujita, T., Ono, T., Furusaki, S. Biotechnol. Prog. (2000) [Pubmed]
  21. Effect of different fixatives on the localization of human melanoma antigens by immunofluorescence. Leong, S.P., Cooperband, S.R., Deckers, P.J., Sutherland, C.M., Cesare, J.F., Krementz, E.T. Oncology (1979) [Pubmed]
  22. Reactivity of trypsin in reverse micelles: neglected role of aggregate size compared to water-pool components. Dasgupta, A., Das, D., Das, P.K. Biochimie (2005) [Pubmed]
  23. The effect of linoleic acid on pH inside sodium bis(2-ethylhexyl)sulfosuccinate reverse micelles in isooctane and on the enzymic activity of soybean lipoxygenase. Rodakiewicz-Nowak, J., Maślakiewicz, P., Haber, J. Eur. J. Biochem. (1996) [Pubmed]
  24. Somatostatin in a water-restricted environment: fluorescence and circular dichroism study in AOT reverse micelles. Bhattacharyya, K., Basak, S. Photochem. Photobiol. (1995) [Pubmed]
  25. Hydrophilic surroundings requisite for the solubilization of proteins related with their hydrophobicity in the AOT reversed micellar extraction. Imai, M., Natsume, T., Naoe, K., Shimizu, M., Ichikawa, S., Furusaki, S. Bioseparation (1996) [Pubmed]
  26. Myelin proteins in reverse micelles: tight lipid association required for insertion of the Folch-Pi proteolipid into a membrane-mimetic system. Vacher, M., Waks, M., Nicot, C. J. Neurochem. (1989) [Pubmed]
  27. Rapid multiresidue extraction method of organochlorinated pesticides from fish feed. Nardelli, V., Palermo, C., Centonze, D. Journal of chromatography. A. (2004) [Pubmed]
  28. Dissociation of pigeon-liver malic enzyme in reverse micelles. Chang, G.G., Huang, T.M., Huang, S.M., Chou, W.Y. Eur. J. Biochem. (1994) [Pubmed]
  29. Partially purified Carica papaya lipase: a versatile biocatalyst for the hydrolytic resolution of (R,S)-2-arylpropionic thioesters in water-saturated organic solvents. Ng, I.S., Tsai, S.W. Biotechnol. Bioeng. (2005) [Pubmed]
  30. Screening of genes involved in isooctane tolerance in Saccharomyces cerevisiae by using mRNA differential display. Miura, S., Zou, W., Ueda, M., Tanaka, A. Appl. Environ. Microbiol. (2000) [Pubmed]
  31. Improved methods for the measurement of acetaldehyde concentrations in plasma and red blood cells. Di Padova, C., Alderman, J., Lieber, C.S. Alcohol. Clin. Exp. Res. (1986) [Pubmed]
  32. Enzymatic production of acetaldehyde from ethanol in rat brain tissue. Gill, K., Menez, J.F., Lucas, D., Deitrich, R.A. Alcohol. Clin. Exp. Res. (1992) [Pubmed]
  33. Determination of josamycin residues in porcine tissues using high-performance liquid chromatography with pre-column derivatization and spectrofluorimetric detection. Leroy, P., Decolin, D., Nicolas, A., Archimbault, P. The Analyst. (1994) [Pubmed]
  34. Activity and spectroscopic properties of bovine liver catalase in sodium bis(2-ethylhexyl)sulfosuccinate/isooctane reverse micelles. Haber, J., Maślakiewicz, P., Rodakiewicz-Nowak, J., Walde, P. Eur. J. Biochem. (1993) [Pubmed]
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