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Gene Review

Cyba  -  cytochrome b-245, alpha polypeptide

Mus musculus

Synonyms: Cytochrome b(558) alpha chain, Cytochrome b-245 light chain, Cytochrome b558 subunit alpha, Neutrophil cytochrome b 22 kDa polypeptide, Superoxide-generating NADPH oxidase light chain subunit, ...
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Biological context of Cyba


Anatomical context of Cyba


  1. Angiotensin II-induced hypertrophy is potentiated in mice overexpressing p22phox in vascular smooth muscle. Weber, D.S., Rocic, P., Mellis, A.M., Laude, K., Lyle, A.N., Harrison, D.G., Griendling, K.K. Am. J. Physiol. Heart Circ. Physiol. (2005) [Pubmed]
  2. Letter regarding article by Becker et al, "Hyperhomocysteinemia, a cardiac metabolic disease: role of nitric oxide and the p22phox subunit of NADPH oxidase". Antoniades, C., Tousoulis, D., Stefanadis, C. Circulation (2005) [Pubmed]
  3. O2 sensing is preserved in mice lacking the gp91 phox subunit of NADPH oxidase. Archer, S.L., Reeve, H.L., Michelakis, E., Puttagunta, L., Waite, R., Nelson, D.P., Dinauer, M.C., Weir, E.K. Proc. Natl. Acad. Sci. U.S.A. (1999) [Pubmed]
  4. Hemodynamic and biochemical adaptations to vascular smooth muscle overexpression of p22phox in mice. Laude, K., Cai, H., Fink, B., Hoch, N., Weber, D.S., McCann, L., Kojda, G., Fukai, T., Schmidt, H.H., Dikalov, S., Ramasamy, S., Gamez, G., Griendling, K.K., Harrison, D.G. Am. J. Physiol. Heart Circ. Physiol. (2005) [Pubmed]
  5. Antioxidant treatment induces transcription and expression of transforming growth factor beta in cultured renal proximal tubular cells. Wolf, G., Hannken, T., Schroeder, R., Zahner, G., Ziyadeh, F.N., Stahl, R.A. FEBS Lett. (2001) [Pubmed]
  6. Developmental expression of NADPH phagocytic oxidase components in mouse embryos. Baehner, R.L., Millar-Groff, S., Bringas, P. Pediatr. Res. (1999) [Pubmed]
  7. Angiotensin II infusion alters vascular function in mouse resistance vessels: roles of O and endothelium. Wang, D., Chabrashvili, T., Borrego, L., Aslam, S., Umans, J.G. J. Vasc. Res. (2006) [Pubmed]
  8. Beneficial effects of candesartan, an angiotensin II type 1 receptor blocker, on beta-cell function and morphology in db/db mice. Shao, J., Iwashita, N., Ikeda, F., Ogihara, T., Uchida, T., Shimizu, T., Uchino, H., Hirose, T., Kawamori, R., Watada, H. Biochem. Biophys. Res. Commun. (2006) [Pubmed]
  9. Ramipril treatment protects against nitrate-induced oxidative stress in eNOS-/- mice: An implication of the NADPH oxidase pathway. Otto, A., Fontaine, J., Berkenboom, G. J. Cardiovasc. Pharmacol. (2006) [Pubmed]
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