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Gene Review

Elf3  -  E74-like factor 3

Mus musculus

Synonyms: ESE-1, ESX, ETS-related transcription factor Elf-3, Epithelial-restricted with serine box, Epithelium-restricted Ets protein ESX, ...
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Disease relevance of Elf3

  • This region appears to be largely responsible for the increase in Elf3 promoter activity that accompanies the differentiation of embryonal carcinoma cells [1].
  • The transcription factor Elf3, which is one of over 25 Ets family members, is expressed in a wide variety of carcinomas and has been shown to promote the transcription of many genes implicated in cancer [1].

High impact information on Elf3


Biological context of Elf3


Other interactions of Elf3

  • ESE-1 transactivates through the regulatory element of cornea-specific K12 keratin [4].


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