Gene Review:
ELF3 - E74-like factor 3 (ets domain...
Homo sapiens
Synonyms:
E74-like factor 3, EPR-1, ERT, ESE-1, ESX, ...
Tsuneyoshi,
Eckel-Mahan,
Prescott,
Singh,
Ladanyi,
Schedin,
Ladanyi,
Saito,
Bittner,
Iwamoto,
Allander,
Wang,
Meltzer,
Kawaguchi,
Tentler,
Prescott,
Oda,
Dosik,
Kaplan,
Matsuda,
Sugimachi,
Yamamoto,
Koto,
Illei,
Brodsky,
Gutierrez-Hartmann,
Xu,
Antonescu,
Tateishi,
McDaniel,
Gutierrez-Hartmann,
Tanaka,
Chen,
- Expression profiling of synovial sarcoma by cDNA microarrays: association of ERBB2, IGFBP2, and ELF3 with epithelial differentiation. Allander, S.V., Illei, P.B., Chen, Y., Antonescu, C.R., Bittner, M., Ladanyi, M., Meltzer, P.S. Am. J. Pathol. (2002)
- A novel epithelial-expressed ETS gene, ELF3: human and murine cDNA sequences, murine genomic organization, human mapping to 1q32.2 and expression in tissues and cancer. Tymms, M.J., Ng, A.Y., Thomas, R.S., Schutte, B.C., Zhou, J., Eyre, H.J., Sutherland, G.R., Seth, A., Rosenberg, M., Papas, T., Debouck, C., Kola, I. Oncogene (1997)
- Partially unspliced and fully spliced ELF3 mRNA, including a new Alu element in human breast cancer. Kaplan, M.H., Wang, X.P., Xu, H.P., Dosik, M.H. Breast Cancer Res. Treat. (2004)
- Sequence-specific enhancer binding protein is responsible for the differential expression of ERT/ESX/ELF-3/ESE-1/jen gene in human gastric cancer cell lines: Implication for the loss of TGF-beta type II receptor expression. Park, S.H., Kim, Y.S., Park, B.K., Hougaard, S., Kim, S.J. Oncogene (2001)
- The oxidative metabolism of estrogen modulates response to ERT/HRT in postmenopausal women. Armamento-Villareal, R.C., Napoli, N., Klug, T., Civitelli, R. Bone (2004)
- The role of hormone replacement therapy in women with a previous diagnosis of breast cancer and a review of possible alternatives. Pritchard, K.I. Ann. Oncol. (2001)
- Is there a role for estrogen replacement therapy in the prevention and treatment of dementia? Birge, S.J. Journal of the American Geriatrics Society. (1996)
- Tobacco smoking and oestrogen replacement are associated with lower total and central fat in monozygotic twins. Samaras, K., Kelly, P.J., Spector, T.D., Chiano, M.N., Campbell, L.V. Int. J. Obes. Relat. Metab. Disord. (1998)
- Alcohol, estrogen replacement therapy, and visuospatial processes in postmenopausal women. Tivis, L.J., Green, M.D., Nixon, S.J., Tivis, R.D. Alcohol. Clin. Exp. Res. (2003)
- Hormone replacement therapy in the menopause: a pro opinion. Smith, H.O., Kammerer-Doak, D.N., Barbo, D.M., Sarto, G.E. CA: a cancer journal for clinicians. (1996)
- Digitized mammography: a clinical trial of postmenopausal women randomly assigned to receive raloxifene, estrogen, or placebo. Freedman, M., San Martin, J., O'Gorman, J., Eckert, S., Lippman, M.E., Lo, S.C., Walls, E.L., Zeng, J. J. Natl. Cancer Inst. (2001)
- ERT for survivors of endometrial cancer? A new trial will resolve debate. McNeil, C. J. Natl. Cancer Inst. (1997)
- Cardiovascular and cancer morbidity and mortality and sudden cardiac death in postmenopausal women on oestrogen replacement therapy (ERT). Sourander, L., Rajala, T., Räihä, I., Mäkinen, J., Erkkola, R., Helenius, H. Lancet (1998)
- Impaired procoagulant-anticoagulant balance during hormone replacement therapy? A randomised, placebo-controlled 12-week study. van Baal, W.M., Emeis, J.J., van der Mooren, M.J., Kessel, H., Kenemans, P., Stehouwer, C.D. Thromb. Haemost. (2000)
- The case for less-than-monthly progestogen in women on HT: is transvaginal ultrasound the key? Goldstein, S.R. Menopause (New York, N.Y.) (2005)
- Metabolic effects of tamoxifen in postmenopause. Sismondi, P., Biglia, N., Giai, M., Sgro, L., Campagnoli, C. Anticancer Res. (1994)
- Safety of estrogen/androgen regimens. Simon, J.A. The Journal of reproductive medicine. (2001)
- Expression of the ETS transcription factor ELF3 in the retinal pigment epithelium. Jobling, A.I., Fang, Z., Koleski, D., Tymms, M.J. Invest. Ophthalmol. Vis. Sci. (2002)
- ESE-1 is a novel transcriptional mediator of angiopoietin-1 expression in the setting of inflammation. Brown, C., Gaspar, J., Pettit, A., Lee, R., Gu, X., Wang, H., Manning, C., Voland, C., Goldring, S.R., Goldring, M.B., Libermann, T.A., Gravallese, E.M., Oettgen, P. J. Biol. Chem. (2004)
- ESX induces transformation and functional epithelial to mesenchymal transition in MCF-12A mammary epithelial cells. Schedin, P.J., Eckel-Mahan, K.L., McDaniel, S.M., Prescott, J.D., Brodsky, K.S., Tentler, J.J., Gutierrez-Hartmann, A. Oncogene (2004)
- Dual function of the epithelial specific ets transcription factor, ELF3, in modulating differentiation. Brembeck, F.H., Opitz, O.G., Libermann, T.A., Rustgi, A.K. Oncogene (2000)
- Positive and negative modulation of the transcriptional activity of the ETS factor ESE-1 through interaction with p300, CREB-binding protein, and Ku 70/86. Wang, H., Fang, R., Cho, J.Y., Libermann, T.A., Oettgen, P. J. Biol. Chem. (2004)
- Over-expression of ERT(ESX/ESE-1/ELF3), an ets-related transcription factor, induces endogenous TGF-beta type II receptor expression and restores the TGF-beta signaling pathway in Hs578t human breast cancer cells. Chang, J., Lee, C., Hahm, K.B., Yi, Y., Choi, S.G., Kim, S.J. Oncogene (2000)
- The ETS transcription factor ESE-1 transforms MCF-12A human mammary epithelial cells via a novel cytoplasmic mechanism. Prescott, J.D., Koto, K.S., Singh, M., Gutierrez-Hartmann, A. Mol. Cell. Biol. (2004)
- ESE-1 is a novel transcriptional mediator of inflammation that interacts with NF-kappa B to regulate the inducible nitric-oxide synthase gene. Rudders, S., Gaspar, J., Madore, R., Voland, C., Grall, F., Patel, A., Pellacani, A., Perrella, M.A., Libermann, T.A., Oettgen, P. J. Biol. Chem. (2001)
- Alveolar and postcranial bone density in postmenopausal women receiving hormone/estrogen replacement therapy: a randomized, double-blind, placebo-controlled trial. Civitelli, R., Pilgram, T.K., Dotson, M., Muckerman, J., Lewandowski, N., Armamento-Villareal, R., Yokoyama-Crothers, N., Kardaris, E.E., Hauser, J., Cohen, S., Hildebolt, C.F. Arch. Intern. Med. (2002)
- Estrogen and progesterone replacement therapy reduces glucocorticoid-induced bone loss. Lukert, B.P., Johnson, B.E., Robinson, R.G. J. Bone Miner. Res. (1992)
- Effect of ets-related transcription factor (ERT) on transforming growth factor (TGF)-beta type II receptor gene expression in human cancer cell lines. Lee, H.J., Chang, J.H., Kim, Y.S., Kim, S.J., Yang, H.K. J. Exp. Clin. Cancer Res. (2003)
- Exon 4-encoded acidic domain in the epithelium-restricted Ets factor, ESX, confers potent transactivating capacity and binds to TATA-binding protein (TBP). Chang, C.H., Scott, G.K., Baldwin, M.A., Benz, C.C. Oncogene (1999)
- Phosphorylation-dependent regulation of stability and transforming potential of ETS transcriptional factor ESE-1 by p21-activated kinase 1. Manavathi, B., Rayala, S.K., Kumar, R. J. Biol. Chem. (2007)
- Expression of Claudin7 Is Tightly Associated with Epithelial Structures in Synovial Sarcomas and Regulated by an Ets Family Transcription Factor, ELF3. Kohno, Y., Okamoto, T., Ishibe, T., Nagayama, S., Shima, Y., Nishijo, K., Shibata, K.R., Fukiage, K., Otsuka, S., Uejima, D., Araki, N., Naka, N., Nakashima, Y., Aoyama, T., Nakayama, T., Nakamura, T., Toguchida, J. J. Biol. Chem. (2006)
- E-cadherin mutation and Snail overexpression as alternative mechanisms of E-cadherin inactivation in synovial sarcoma. Saito, T., Oda, Y., Kawaguchi, K., Sugimachi, K., Yamamoto, H., Tateishi, N., Tanaka, K., Matsuda, S., Iwamoto, Y., Ladanyi, M., Tsuneyoshi, M. Oncogene (2004)