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Gene Review

ykt-6  -  Protein YKT-6

Caenorhabditis elegans

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Disease relevance of synaptobrevin


High impact information on synaptobrevin


Biological context of synaptobrevin


Anatomical context of synaptobrevin


Associations of synaptobrevin with chemical compounds

  • Brief mechanical stimulation during larval development rescued the expression of GFP-tagged glutamate receptors but not GFP-tagged synaptobrevin [9].

Other interactions of synaptobrevin


  1. A neomorphic syntaxin mutation blocks volatile-anesthetic action in Caenorhabditis elegans. van Swinderen, B., Saifee, O., Shebester, L., Roberson, R., Nonet, M.L., Crowder, C.M. Proc. Natl. Acad. Sci. U.S.A. (1999) [Pubmed]
  2. A genetic interaction between the vesicular acetylcholine transporter VAChT/UNC-17 and synaptobrevin/SNB-1 in C. elegans. Sandoval, G.M., Duerr, J.S., Hodgkin, J., Rand, J.B., Ruvkun, G. Nat. Neurosci. (2006) [Pubmed]
  3. Factors regulating the abundance and localization of synaptobrevin in the plasma membrane. Dittman, J.S., Kaplan, J.M. Proc. Natl. Acad. Sci. U.S.A. (2006) [Pubmed]
  4. Epileptic-like convulsions associated with LIS-1 in the cytoskeletal control of neurotransmitter signaling in Caenorhabditis elegans. Williams, S.N., Locke, C.J., Braden, A.L., Caldwell, K.A., Caldwell, G.A. Hum. Mol. Genet. (2004) [Pubmed]
  5. Synaptic transmission deficits in Caenorhabditis elegans synaptobrevin mutants. Nonet, M.L., Saifee, O., Zhao, H., Rand, J.B., Wei, L. J. Neurosci. (1998) [Pubmed]
  6. UNC-11, a Caenorhabditis elegans AP180 homologue, regulates the size and protein composition of synaptic vesicles. Nonet, M.L., Holgado, A.M., Brewer, F., Serpe, C.J., Norbeck, B.A., Holleran, J., Wei, L., Hartwieg, E., Jorgensen, E.M., Alfonso, A. Mol. Biol. Cell (1999) [Pubmed]
  7. The short coiled-coil domain-containing protein UNC-69 cooperates with UNC-76 to regulate axonal outgrowth and normal presynaptic organization in Caenorhabditis elegans. Su, C.W., Tharin, S., Jin, Y., Wightman, B., Spector, M., Meili, D., Tsung, N., Rhiner, C., Bourikas, D., Stoeckli, E., Garriga, G., Horvitz, H.R., Hengartner, M.O. J. Biol. (2006) [Pubmed]
  8. GLR-1, a non-NMDA glutamate receptor homolog, is critical for long-term memory in Caenorhabditis elegans. Rose, J.K., Kaun, K.R., Chen, S.H., Rankin, C.H. J. Neurosci. (2003) [Pubmed]
  9. Decreased sensory stimulation reduces behavioral responding, retards development, and alters neuronal connectivity in Caenorhabditis elegans. Rose, J.K., Sangha, S., Rai, S., Norman, K.R., Rankin, C.H. J. Neurosci. (2005) [Pubmed]
  10. Mutations in Caenorhabditis elegans cytoplasmic dynein components reveal specificity of neuronal retrograde cargo. Koushika, S.P., Schaefer, A.M., Vincent, R., Willis, J.H., Bowerman, B., Nonet, M.L. J. Neurosci. (2004) [Pubmed]
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