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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Gene Review

pre  -  recombination protein

Staphylococcus aureus

 
 
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Disease relevance of pre

  • The in vivo studies showed that when CVCs were pre-treated with BMAP-28 or with a high dose of antibiotics, biofilm bacterial load was reduced from 10(7) to 10(3) CFU/mL and bacteremia reduced from 10(3) to 10(1) CFU/mL [1].
  • Gender differences in infective endocarditis: pre- and co-morbid conditions lead to different management and outcomes in female patients [2].
  • In conclusion, differences between genders in treatment and outcomes frequently reported in patients with IE most likely result from pre- and co-existing conditions such as diabetes mellitus, renal failure requiring hemodialysis, and chronic immunosuppression [2].
  • The epidemiologic landscape of causative pathogens and clinical characteristics of bacterial meningitis varies with several clinical factors including preceding/pre-existent medical and/or surgical conditions, modes of contraction, geographic distributions, status of vaccinations, the study time periods and differences among age groups [3].
  • In adults, a hematogenous spread to a pre-existing altered thyroid gland is often the postulated pathogenetic mechanism, and it is exceedingly rare in the United States. We report the case of an 81-yr-old woman with acute suppurative thyroiditis secondary to Escherichia coli (E. coli) infection [4].
 

High impact information on pre

  • Post-exposure gentamicin MIC values were within one tube dilution of the pre-exposure MIC value (0.25 mg/L) [5].
  • These pre-incubated bacteria were phagocytosed by neutrophils at an increased level in vitro in a mouse model [6].
  • However, pSES22 was similar to several members of a diverse group of small plasmids, all of which carried closely related plasmid backbones consisting of the genes repU and pre/mob, but differed in their resistance genes [7].
 

Analytical, diagnostic and therapeutic context of pre

  • The value of pre-operative aspiration in the diagnosis of an infected prosthetic knee: a retrospective study and review of literature [8].

References

  1. Pre-treatment of central venous catheters with the cathelicidin BMAP-28 enhances the efficacy of antistaphylococcal agents in the treatment of experimental catheter-related infection. Cirioni, O., Giacometti, A., Ghiselli, R., Bergnach, C., Orlando, F., Mocchegiani, F., Silvestri, C., Licci, A., Skerlavaj, B., Zanetti, M., Saba, V., Scalise, G. Peptides (2006) [Pubmed]
  2. Gender differences in infective endocarditis: pre- and co-morbid conditions lead to different management and outcomes in female patients. Aksoy, O., Meyer, L.T., Cabell, C.H., Kourany, W.M., Pappas, P.A., Sexton, D.J. Scand. J. Infect. Dis. (2007) [Pubmed]
  3. Culture-proven bacterial meningitis in elderly patients in southern Taiwan: clinical characteristics and prognostic factors. Chang, C.C., Lu, C.H., Huang, C.R., Chuang, Y.C., Tsai, N.W., Chen, S.F., Chang, H.W., Chang, W.N. Acta neurologica Taiwanica. (2006) [Pubmed]
  4. A case of acute suppurative thyroiditis complicated by thyrotoxicosis. Sicilia, V., Mezitis, S. J. Endocrinol. Invest. (2006) [Pubmed]
  5. Consistent rates of kill of Staphylococcus aureus by gentamicin over a 6-fold clinical concentration range in an in vitro pharmacodynamic model (IVPDM). Schafer, J.A., Hovde, L.B., Rotschafer, J.C. J. Antimicrob. Chemother. (2006) [Pubmed]
  6. An immunogenicity study of a newly fusion protein Cna-FnBP vaccinated against Staphylococcus aureus infections in a mice model. Zhou, H., Xiong, Z.Y., Li, H.P., Zheng, Y.L., Jiang, Y.Q. Vaccine (2006) [Pubmed]
  7. Characterization of a novel type of MLSB resistance plasmid from Staphylococcus saprophyticus carrying a constitutively expressed erm(C) gene. Hauschild, T., Lüthje, P., Schwarz, S. Vet. Microbiol. (2006) [Pubmed]
  8. The value of pre-operative aspiration in the diagnosis of an infected prosthetic knee: a retrospective study and review of literature. Van den Bekerom, M.P., Stuyck, J. Acta orthopaedica Belgica. (2006) [Pubmed]
 
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