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pre  -  Pre

Staphylococcus aureus

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Disease relevance of pre

  • These results provide evidence that ArsC from pI258 evolved from LMW PTPase by the grafting of a redox function onto a pre-existing catalytic site and that its evolutionary origin is different from those of arsenate reductases from Escherichia coli plasmid R773 and from Saccharomyces cerevisiae [1].
  • Patients with pre-existing lung damage are susceptible to NTM, but their prevalence in bronchiectasis is unknown [2].
  • The accumulation of a strain of Staphylococcus epidermidis on silicone rubber catheter segments pre-exposed to glycopeptide antibiotics was examined [3].
  • Two previous inoculation methods i.e. that of pre- and direct inoculation were studied with two bacterial isolates namely Staphylococcus aureus and epidermidis, on titanium and stainless steel metallic implants [4].
  • The in vivo studies showed that when CVCs were pre-treated with BMAP-28 or with a high dose of antibiotics, biofilm bacterial load was reduced from 10(7) to 10(3) CFU/mL and bacteremia reduced from 10(3) to 10(1) CFU/mL [5].

Psychiatry related information on pre

  • The epidemiologic landscape of causative pathogens and clinical characteristics of bacterial meningitis varies with several clinical factors including preceding/pre-existent medical and/or surgical conditions, modes of contraction, geographic distributions, status of vaccinations, the study time periods and differences among age groups [6].

High impact information on pre


Chemical compound and disease context of pre


Biological context of pre

  • In the fourth case, the IS257 elements flanked a pT181-like plasmid with one IS257 in the repC coding sequence and the other within the recombinase (pre) coding sequence, so that a section of the pT181 sequence was deleted [16].
  • The rise in rectal temperature following intravenous endotoxin injection immediately pre- and postpartum was significantly less than that of the same ewes 5 weeks later [17].
  • Bacteriological quality and associated public health risk of pre-processed bovine milk in Trinidad [18].
  • The presence of fibrin or isolated platelets significantly increased bacterial adhesion compared to surfaces pre-adsorbed with albumin [12].
  • As more data are collected, inhaled antibiotics, selective digestive decontamination, and enhancement of host defenses by cytokines and pre-formed antibodies may emerge as useful approaches [19].

Anatomical context of pre

  • Another novel finding of this study was the fact that both 15d-PGJ2 and ciglitazone were capable of attenuating pre-existing astrocyte activation, indicating their potential benefit in a therapeutic setting [20].
  • 3. Pre-treatments of L-group with adequate doses of aminoguanidine prevented the neutrophil migration failure and improved the survival of the animals (pre-treated: 43%; untreated: 0% survival) [21].
  • A total of 513 pathogens were isolated from the pre-treatment sputum specimens of 400 (49%) patients [22].
  • A negative correlation was found between lymphocyte collection efficacy (median = 38%) and pre ECP-apheresis lymphocyte count (r = 0.4, p = 0.00001) [23].
  • The total test time was 10-15 min when pre-spotted and blocked membranes were used [24].

Associations of pre with chemical compounds

  • Post-exposure gentamicin MIC values were within one tube dilution of the pre-exposure MIC value (0.25 mg/L) [25].
  • To control both types of infection, a protocol was implemented based on pre 1990's parenteral and enteral antimicrobials together with strict hygiene [26].
  • Improvements in drug loading from 1.8% to 6.7% w/w and distribution in the matrices were obtained by pre-cooling the suspension to 4 degrees C. Gradual release of approximately 80% of the GS content occurred over 11 weeks in PBS at 37 degrees C and low amounts of antibiotic were measured up to 20 weeks [27].
  • In this in vitro study, we investigated the efficacy of gentamicin loading of bone cement and pre- and postoperative administration of cefuroxime in the prevention of biofilm formation by clinical isolates [28].
  • In group T a pre-operative chlorhexidine rinse was used, whilst in group C sterile water was used [29].

Analytical, diagnostic and therapeutic context of pre


  1. Arsenate reductase from S. aureus plasmid pI258 is a phosphatase drafted for redox duty. Zegers, I., Martins, J.C., Willem, R., Wyns, L., Messens, J. Nat. Struct. Biol. (2001) [Pubmed]
  2. Non-tuberculous mycobacteria in patients with bronchiectasis. Wickremasinghe, M., Ozerovitch, L.J., Davies, G., Wodehouse, T., Chadwick, M.V., Abdallah, S., Shah, P., Wilson, R. Thorax (2005) [Pubmed]
  3. Binding of teicoplanin and vancomycin to polymer surfaces. Wilcox, M.H., Winstanley, T.G., Spencer, R.C. J. Antimicrob. Chemother. (1994) [Pubmed]
  4. Adhesion of Staphylococcus to orthopaedic metals, an in vivo study. Sheehan, E., McKenna, J., Mulhall, K.J., Marks, P., McCormack, D. J. Orthop. Res. (2004) [Pubmed]
  5. Pre-treatment of central venous catheters with the cathelicidin BMAP-28 enhances the efficacy of antistaphylococcal agents in the treatment of experimental catheter-related infection. Cirioni, O., Giacometti, A., Ghiselli, R., Bergnach, C., Orlando, F., Mocchegiani, F., Silvestri, C., Licci, A., Skerlavaj, B., Zanetti, M., Saba, V., Scalise, G. Peptides (2006) [Pubmed]
  6. Culture-proven bacterial meningitis in elderly patients in southern Taiwan: clinical characteristics and prognostic factors. Chang, C.C., Lu, C.H., Huang, C.R., Chuang, Y.C., Tsai, N.W., Chen, S.F., Chang, H.W., Chang, W.N. Acta neurologica Taiwanica. (2006) [Pubmed]
  7. Granulocyte function in grancalcin-deficient mice. Roes, J., Choi, B.K., Power, D., Xu, P., Segal, A.W. Mol. Cell. Biol. (2003) [Pubmed]
  8. In vivo treatment with granulocyte colony-stimulating factor results in divergent effects on neutrophil functions measured in vitro. Leavey, P.J., Sellins, K.S., Thurman, G., Elzi, D., Hiester, A., Silliman, C.C., Zerbe, G., Cohen, J.J., Ambruso, D.R. Blood (1998) [Pubmed]
  9. Mast cells have a pivotal role in TNF-independent lymph node hypertrophy and the mobilization of Langerhans cells in response to bacterial peptidoglycan. Jawdat, D.M., Rowden, G., Marshall, J.S. J. Immunol. (2006) [Pubmed]
  10. Chemotaxis inhibitory protein of Staphylococcus aureus binds specifically to the C5a and formylated peptide receptor. Postma, B., Poppelier, M.J., van Galen, J.C., Prossnitz, E.R., van Strijp, J.A., de Haas, C.J., van Kessel, K.P. J. Immunol. (2004) [Pubmed]
  11. The effect of oral decontamination with clindamycin palmitate on the incidence of bacteremia after esophageal dilation: a prospective trial. Hirota, W.K., Wortmann, G.W., Maydonovitch, C.L., Chang, A.S., Midkiff, R.B., Wong, R.K., Moses, F.M. Gastrointest. Endosc. (1999) [Pubmed]
  12. Bacterial adhesion on polyurethane surfaces conditioned with thrombus components. Baumgartner, J.N., Cooper, S.L. ASAIO journal (American Society for Artificial Internal Organs : 1992) (1996) [Pubmed]
  13. Povidone-iodine liposomes--an overview. Reimer, K., Fleischer, W., Brögmann, B., Schreier, H., Burkhard, P., Lanzendörfer, A., Gümbel, H., Hoekstra, H., Behrens-Baumann, W. Dermatology (Basel) (1997) [Pubmed]
  14. Pre-steady state beta-lactamase kinetics. Observation of a covalent intermediate during turnover of a fluorescent cephalosporin by the beta-lactamase of STaphylococcus aureus PC1. Anderson, E.G., Pratt, R.F. J. Biol. Chem. (1981) [Pubmed]
  15. Chromosomal gene transfer during conjugation by Staphylococcus aureus is mediated by transposon-facilitated mobilization. Stout, V.G., Iandolo, J.J. J. Bacteriol. (1990) [Pubmed]
  16. Integration of pT181-like tetracycline resistance plasmids into large staphylococcal plasmids involves IS257. Werckenthin, C., Schwarz, S., Roberts, M.C. Antimicrob. Agents Chemother. (1996) [Pubmed]
  17. Fever response of sheep in the peripartum period to gram-negative and gram-positive pyrogens. Goelst, K., Mitchell, D., MacPhail, A.P., Cooper, K.E., Laburn, H. Pflugers Arch. (1992) [Pubmed]
  18. Bacteriological quality and associated public health risk of pre-processed bovine milk in Trinidad. Adesiyun, A.A. Int. J. Food Microbiol. (1994) [Pubmed]
  19. The impact of tracheal intubation on host defenses and risks for nosocomial pneumonia. Levine, S.A., Niederman, M.S. Clin. Chest Med. (1991) [Pubmed]
  20. 15-deoxy-Delta12,14-prostaglandin J2 (15d-PGJ2) and ciglitazone modulate Staphylococcus aureus-dependent astrocyte activation primarily through a PPAR-gamma-independent pathway. Phulwani, N.K., Feinstein, D.L., Gavrilyuk, V., Akar, C., Kielian, T. J. Neurochem. (2006) [Pubmed]
  21. Involvement of NO in the failure of neutrophil migration in sepsis induced by Staphylococcus aureus. Crosara-Alberto, D.P., Darini, A.L., Inoue, R.Y., Silva, J.S., Ferreira, S.H., Cunha, F.Q. Br. J. Pharmacol. (2002) [Pubmed]
  22. Randomized, double-blind study of short-course (5 day) grepafloxacin versus 10 day clarithromycin in patients with acute bacterial exacerbations of chronic bronchitis. Langan, C.E., Zuck, P., Vogel, F., McIvor, A., Peirzchala, W., Smakal, M., Staley, H., Marr, C. J. Antimicrob. Chemother. (1999) [Pubmed]
  23. Successful extracorporeal photochemotherapy for chronic graft-versus-host disease in pediatric patients. Halle, P., Paillard, C., D'Incan, M., Bordigoni, P., Piguet, C., De Lumley, L., Stephan, J.L., Berger, M., Rapatel, C., Deméocq, F., Kanold, J. J. Hematother. Stem Cell Res. (2002) [Pubmed]
  24. Detection of Staphylococcus aureus with biotinylated monoclonal antibodies directed against staphylococcal TNase complexed to avidin-peroxidase in a rapid sandwich enzyme-linked immunofiltration assay (sELIFA). Brakstad, O.G., Maeland, J.A. J. Med. Microbiol. (1993) [Pubmed]
  25. Consistent rates of kill of Staphylococcus aureus by gentamicin over a 6-fold clinical concentration range in an in vitro pharmacodynamic model (IVPDM). Schafer, J.A., Hovde, L.B., Rotschafer, J.C. J. Antimicrob. Chemother. (2006) [Pubmed]
  26. A prospective study of septicaemia on a paediatric oncology unit: a three-year experience at The Royal Liverpool Children's Hospital, Alder Hey, UK. Paulus, S.C., van Saene, H.K., Hemsworth, S., Hughes, J., Ng, A., Pizer, B.L. Eur. J. Cancer (2005) [Pubmed]
  27. Delivery of the antibiotic gentamicin sulphate from precipitation cast matrices of polycaprolactone. Chang, H.I., Perrie, Y., Coombes, A.G. Journal of controlled release : official journal of the Controlled Release Society. (2006) [Pubmed]
  28. Biofilm formation by bacteria isolated from retrieved failed prosthetic hip implants in an in vitro model of hip arthroplasty antibiotic prophylaxis. Tunney, M.M., Dunne, N., Einarsson, G., McDowell, A., Kerr, A., Patrick, S. J. Orthop. Res. (2007) [Pubmed]
  29. The effects of an immediately pre-surgical chlorhexidine oral rinse on the bacterial contaminants of bone debris collected during dental implant surgery. Young, M.P., Korachi, M., Carter, D.H., Worthington, H.V., McCord, J.F., Drucker, D.B. Clinical oral implants research. (2002) [Pubmed]
  30. Pinpoint targeted immunosuppression: anti-CD20/MMF desensitization with anti-CD25 in successful ABO-incompatible kidney transplantation without splenectomy. Saito, K., Nakagawa, Y., Suwa, M., Kumagai, N., Tanikawa, T., Nishiyama, T., Ueno, M., Gejyo, F., Nishi, S., Takahashi, K. Xenotransplantation (2006) [Pubmed]
  31. Inclusion of a non-immunoglobulin binding protein in two-site ELISA for quantification of human serum proteins without interference by heterophilic serum antibodies. Andersson, M., Rönnmark, J., Areström, I., Nygren, P.A., Ahlborg, N. J. Immunol. Methods (2003) [Pubmed]
  32. Outbreak of surgical wound infections associated with total hip arthroplasty. Beck-Sague, C.M., Chong, W.H., Roy, C., Anderson, R., Jarvis, W.R. Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America. (1992) [Pubmed]
  33. Guidelines for monitoring bulk tank milk somatic cell and bacterial counts. Jayarao, B.M., Pillai, S.R., Sawant, A.A., Wolfgang, D.R., Hegde, N.V. J. Dairy Sci. (2004) [Pubmed]
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