Gene Review:
Gzma - granzyme A
Rattus norvegicus
- Cytotoxicity with target DNA breakdown by rat basophilic leukemia cells expressing both cytolysin and granzyme A. Shiver, J.W., Su, L., Henkart, P.A. Cell (1992)
- Characterization of structural determinants of granzyme B reveals potent mediators of extended substrate specificity. Ruggles, S.W., Fletterick, R.J., Craik, C.S. J. Biol. Chem. (2004)
- Granzyme A activates an endoplasmic reticulum-associated caspase-independent nuclease to induce single-stranded DNA nicks. Beresford, P.J., Zhang, D., Oh, D.Y., Fan, Z., Greer, E.L., Russo, M.L., Jaju, M., Lieberman, J. J. Biol. Chem. (2001)
- Purification and identification of a binding protein for pancreatic secretory trypsin inhibitor: a novel role of the inhibitor as an anti-granzyme A. Tsuzuki, S., Kokado, Y., Satomi, S., Yamasaki, Y., Hirayasu, H., Iwanaga, T., Fushiki, T. Biochem. J. (2003)
- Differential expression of granzyme A and granzyme B proteases and their secretion by fresh rat natural killer cells (NK) and lymphokine-activated killer cells with NK phenotype (LAK-NK). Velotti, F., Palmieri, G., D'Ambrosio, D., Piccoli, M., Frati, L., Santoni, A. Eur. J. Immunol. (1992)
- Synergistic roles of granzymes A and B in mediating target cell death by rat basophilic leukemia mast cell tumors also expressing cytolysin/perforin. Nakajima, H., Park, H.L., Henkart, P.A. J. Exp. Med. (1995)
- Expression of human recombinant granzyme A zymogen and its activation by the cysteine proteinase cathepsin C. Kummer, J.A., Kamp, A.M., Citarella, F., Horrevoets, A.J., Hack, C.E. J. Biol. Chem. (1996)
- Granzyme A expression by normal rat natural killer (NK) cells in vivo and by interleukin 2-activated NK cells in vitro. Velotti, F., Palmieri, G., Morrone, S., Piccoli, M., Frati, L., Santoni, A. Eur. J. Immunol. (1989)
- Non-granular proteolytic enzymes of rat interleukin-2-activated natural killer cells. III. Enhancement of A-NKP 1, 2, and 3 proteolytic activities (cleaving after Arg, Phe and Pro) in response to interleukin-2. Kitson, R.P., Miller, C.A., Goldfarb, R.H. Nat. Immun. (1995)
- Decreased IFN-gamma and IL-2 mRNA expression in peripheral tolerance to heart allografts with conserved granzyme A, perforin, and MHC antigens mRNA expression. Bugeon, L., Cuturi, M.C., Paineau, J., Chabannes, D., Soulillou, J.P. Transplant. Proc. (1993)
- Decreased anti-donor major histocompatibility complex class I and increased class II alloantibody response in allograft tolerance in adult rats. Cuturi, M.C., Josien, R., Cantarovich, D., Bugeon, L., Anegon, I., Menoret, S., Smit, H., Douillard, P., Soulillou, J.P. Eur. J. Immunol. (1994)