The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

PYCARD  -  PYD and CARD domain containing

Bos taurus

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of ASC

  • AIMS: The present study was designed to determine the individual and combined effects of acidified sodium chlorite (ASC, 0.1%, 24 +/- 1 degrees C), cetylpyridinium chloride (CPC, 0.5%, 24 +/- 1 degrees C) and hot water (HW, 93 +/- 1 degrees C) treatments on the survival of Listeria monocytogenes and Staphylococcus aureus [1].

High impact information on ASC


Associations of ASC with chemical compounds

  • Specific transport components of lysine uptake were estimated to be: 63% occurring through the cationic (Y+) system, 17% via the neutral alanine (A) and alanine, serine, cysteine (ASC) amino acid transport systems, and 20% through nonsaturable processes [5].
  • The specific transport components of methionine uptake were estimated as 54% occurring through the neutral branched chain leucine (L) systems, 28% through the ASC system, 15% through the A system and 25% through nonsaturable processes [5].
  • Phase 1 tested water, SH, PAA, LA, and 0.5% CPC on meat inoculated with non-acid-habituated pathogen populations, whereas phase 2 tested water, SC, AH, ASC, LA, and 0.1% CPC on meat inoculated with acid- and non-acid-habituated populations [6].
  • Reductions from phase 2 for acid-habituated cells increased in the order NT = water = SC < ASC = LA = AH < CPC, whereas on non-acid-habituated cells the order observed was NT = water = SC < AH = ASC < LA < CPC [6].


  1. Effects of acidified sodium chlorite, cetylpyridinium chloride and hot water on populations of Listeria monocytogenes and Staphylococcus aureus on beef. Ozdemir, H., Koluman, A., Yildirim, Y. Lett. Appl. Microbiol. (2006) [Pubmed]
  2. Caspy, a zebrafish caspase, activated by ASC oligomerization is required for pharyngeal arch development. Masumoto, J., Zhou, W., Chen, F.F., Su, F., Kuwada, J.Y., Hidaka, E., Katsuyama, T., Sagara, J., Taniguchi, S., Ngo-Hazelett, P., Postlethwait, J.H., Núñez, G., Inohara, N. J. Biol. Chem. (2003) [Pubmed]
  3. Neutral amino acid transport in bovine articular chondrocytes. Barker, G.A., Wilkins, R.J., Golding, S., Ellory, J.C. J. Physiol. (Lond.) (1999) [Pubmed]
  4. Na+ -dependent neutral amino acid transporters A, ASC, and N of the blood-brain barrier: mechanisms for neutral amino acid removal. O'Kane, R.L., Viña, J.R., Simpson, I., Hawkins, R.A. Am. J. Physiol. Endocrinol. Metab. (2004) [Pubmed]
  5. Identification of methionine and lysine transport systems in cattle small intestine. Guerino, F., Baumrucker, C.R. J. Anim. Sci. (1987) [Pubmed]
  6. Effect of simulated spray chilling with chemical solutions on acid-habituated and non-acid-habituated Escherichia coli O157:H7 cells attached to beef carcass tissue. Stopforth, J.D., Yoon, Y., Belk, K.E., Scanga, J.A., Kendall, P.A., Smith, G.C., Sofos, J.N. J. Food Prot. (2004) [Pubmed]
WikiGenes - Universities