Gene Review:
DNMT3L - DNA (cytosine-5-)-methyltransferase 3-like
Homo sapiens
Synonyms:
DNA (cytosine-5)-methyltransferase 3-like, MGC1090
- DNMT3L is a novel marker and is essential for the growth of human embryonal carcinoma. Minami, K., Chano, T., Kawakami, T., Ushida, H., Kushima, R., Okabe, H., Okada, Y., Okamoto, K. Clin. Cancer Res. (2010)
- The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a. Chedin, F., Lieber, M.R., Hsieh, C.L. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Reconstitution and mechanism of the stimulation of de novo methylation by human DNMT3L. Kareta, M.S., Botello, Z.M., Ennis, J.J., Chou, C., Chédin, F. J. Biol. Chem. (2006)
- Evolution of the vertebrate DNMT3 gene family: a possible link between existence of DNMT3L and genomic imprinting. Yokomine, T., Hata, K., Tsudzuki, M., Sasaki, H. Cytogenet. Genome Res. (2006)
- Isolation and initial characterization of a novel zinc finger gene, DNMT3L, on 21q22.3, related to the cytosine-5-methyltransferase 3 gene family. Aapola, U., Kawasaki, K., Scott, H.S., Ollila, J., Vihinen, M., Heino, M., Shintani, A., Kawasaki, K., Minoshima, S., Krohn, K., Antonarakis, S.E., Shimizu, N., Kudoh, J., Peterson, P. Genomics (2000)
- Expression of mRNAs for DNA methyltransferases and methyl-CpG-binding proteins in the human female germ line, preimplantation embryos, and embryonic stem cells. Huntriss, J., Hinkins, M., Oliver, B., Harris, S.E., Beazley, J.C., Rutherford, A.J., Gosden, R.G., Lanzendorf, S.E., Picton, H.M. Mol. Reprod. Dev. (2004)
- Imprinting regulator DNMT3L is a transcriptional repressor associated with histone deacetylase activity. Aapola, U., Liiv, I., Peterson, P. Nucleic Acids Res. (2002)