The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

SLC2A3  -  solute carrier family 2 (facilitated...

Gallus gallus

Synonyms: CEF-GT3, GLUT3
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on SLC2A3

  • Surprisingly, these clones corresponded to a message encoding a protein which has most sequence similarity to the human type 3 glucose transporter and which we refer to as CEF-GT3 [1].
  • When the CEF-GT3 cDNA was expressed in rat fibroblasts, a three-to fourfold enhancement of 2-deoxyglucose uptake was observed, indicating that CEF-GT3 is a functional glucose transporter [1].
  • In embryonic skeletal muscle, the levels of Glut1 and Glut3 proteins and mRNA were highest very early, and declined severely by mid-development [2].
  • Bursacyte glucose transporter-3 (Glut-3) mRNA abundance increased from d1 to d14 and hexokinase-1 (HK-1) mRNA abundance was maximum on e20 (P < 0.05) [3].
  • The aim of this study was to identify the extent of mRNA expression of GLUT1, GLUT2, GLUT3 and GLUT8 in chickens intrinsically lacking GLUT4 [4].

Biological context of SLC2A3


Anatomical context of SLC2A3


Associations of SLC2A3 with chemical compounds

  • The data suggest that GLUT-3 cell surface expression may be resistant to the suppressive effects of ethanol in the developing brain of ethanol-treated embryos [6].

Other interactions of SLC2A3


Analytical, diagnostic and therapeutic context of SLC2A3


  1. Differential regulation of glucose transporter isoforms by the src oncogene in chicken embryo fibroblasts. White, M.K., Rall, T.B., Weber, M.J. Mol. Cell. Biol. (1991) [Pubmed]
  2. Differential expression of glucose transporters during chick embryogenesis. Carver, F.M., Shibley, I.A., Pennington, J.S., Pennington, S.N. Cell. Mol. Life Sci. (2001) [Pubmed]
  3. Energy Metabolism in Developing Chicken Lymphocytes Is Altered during the Embryonic to Posthatch Transition. Rudrappa, S.G., Humphrey, B.D. J. Nutr. (2007) [Pubmed]
  4. Characterisation of glucose transporter (GLUT) gene expression in broiler chickens. Kono, T., Nishida, M., Nishiki, Y., Seki, Y., Sato, K., Akiba, Y. Br. Poult. Sci. (2005) [Pubmed]
  5. Antiangiogenic hypoxic cytotoxin TX-402 inhibits hypoxia-inducible factor 1 signaling pathway. Nagasawa, H., Mikamo, N., Nakajima, Y., Matsumoto, H., Uto, Y., Hori, H. Anticancer Res. (2003) [Pubmed]
  6. Increased intracellular localization of brain GLUT-1 transporter in response to ethanol during chick embryogenesis. Carver, F.M., Shibley, I.A., Miles, D.S., Pennington, J.S., Pennington, S.N. Am. J. Physiol. (1999) [Pubmed]
  7. Identification of the presenilins in hematopoietic cells with localization of presenilin 1 to neutrophil and platelet granules. Mirinics, Z.K., Calafat, J., Udby, L., Lovelock, J., Kjeldsen, L., Rothermund, K., Sisodia, S.S., Borregaard, N., Corey, S.J. Blood Cells Mol. Dis. (2002) [Pubmed]
WikiGenes - Universities