Gene Review:
Tak1 - TGF-beta activated kinase 1
Drosophila melanogaster
Synonyms:
CG1388, CG18492, D-TAK, D-tak, D10, ...
- Targeting of TAK1 by the NF-kappa B protein Relish regulates the JNK-mediated immune response in Drosophila. Park, J.M., Brady, H., Ruocco, M.G., Sun, H., Williams, D., Lee, S.J., Kato, T., Richards, N., Chan, K., Mercurio, F., Karin, M., Wasserman, S.A. Genes Dev. (2004)
- Role of the TAK1-NLK-STAT3 pathway in TGF-beta-mediated mesoderm induction. Ohkawara, B., Shirakabe, K., Hyodo-Miura, J., Matsuo, R., Ueno, N., Matsumoto, K., Shibuya, H. Genes Dev. (2004)
- Mutations in the Drosophila dTAK1 gene reveal a conserved function for MAPKKKs in the control of rel/NF-kappaB-dependent innate immune responses. Vidal, S., Khush, R.S., Leulier, F., Tzou, P., Nakamura, M., Lemaitre, B. Genes Dev. (2001)
- The role of the Drosophila TAK homologue dTAK during development. Mihaly, J., Kockel, L., Gaengel, K., Weber, U., Bohmann, D., Mlodzik, M. Mech. Dev. (2001)
- TAK1 participates in c-Jun N-terminal kinase signaling during Drosophila development. Takatsu, Y., Nakamura, M., Stapleton, M., Danos, M.C., Matsumoto, K., O'Connor, M.B., Shibuya, H., Ueno, N. Mol. Cell. Biol. (2000)
- Cooperative control of Drosophila immune responses by the JNK and NF-kappaB signaling pathways. Delaney, J.R., Stöven, S., Uvell, H., Anderson, K.V., Engström, Y., Mlodzik, M. EMBO J. (2006)
- A genetic screen targeting the tumor necrosis factor/Eiger signaling pathway: identification of Drosophila TAB2 as a functionally conserved component. Geuking, P., Narasimamurthy, R., Basler, K. Genetics (2005)
- Hypersensitivity to mitomycin C cell-killing in Roberts syndrome fibroblasts with, but not without, the heterochromatin abnormality. Burns, M.A., Tomkins, D.J. Mutat. Res. (1989)
- Stimulus-specific requirements for MAP3 kinases in activating the JNK pathway. Chen, W., White, M.A., Cobb, M.H. J. Biol. Chem. (2002)
- The role of ubiquitination in Drosophila innate immunity. Zhou, R., Silverman, N., Hong, M., Liao, D.S., Chung, Y., Chen, Z.J., Maniatis, T. J. Biol. Chem. (2005)
- Immune activation of NF-kappaB and JNK requires Drosophila TAK1. Silverman, N., Zhou, R., Erlich, R.L., Hunter, M., Bernstein, E., Schneider, D., Maniatis, T. J. Biol. Chem. (2003)