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Gene Review

FGF7  -  fibroblast growth factor 7

Gallus gallus

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High impact information on FGF7


Anatomical context of FGF7

  • Our results suggest that FGF7 and FGF10 directly induce the AER in the ectoderm both of the flank and of the dorsal midline and that these two regions have the competence for AER induction [1].
  • Here we report that FGF7 and FGF10, members of the fibroblast growth factor family, are the best candidates for the direct inducer of the AER [1].
  • Fgf10 is expressed both in the proventricular and gizzard mesenchyme while Fgf7 is expressed only in gizzard mesenchyme [4].
  • To provide basic data to analyze function of FGFs in the developing gut, here we cloned Fgf7 and studied expression patterns of Fgf7, Fgf10 and Fgfr1-4 during the development of chicken stomach (glandular stomach; proventriculus and muscular stomach; gizzard) [4].


  1. FGF7 and FGF10 directly induce the apical ectodermal ridge in chick embryos. Yonei-Tamura, S., Endo, T., Yajima, H., Ohuchi, H., Ide, H., Tamura, K. Dev. Biol. (1999) [Pubmed]
  2. Mitogenic effects of fibroblast growth factors on chicken granulosa and theca cells in vitro. Roberts, R.D., Ellis, R.C. Biol. Reprod. (1999) [Pubmed]
  3. Comparative genomics on FGF7, FGF10, FGF22 orthologs, and identification of fgf25. Katoh, Y., Katoh, M. Int. J. Mol. Med. (2005) [Pubmed]
  4. Expression of Fgf10 and Fgf receptors during development of the embryonic chicken stomach. Shin, M., Watanuki, K., Yasugi, S. Gene Expr. Patterns (2005) [Pubmed]
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