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Gene Review

Cortactin  -  CG3637 gene product from transcript CG3637-RD

Drosophila melanogaster

Synonyms: CG3637, Dmel\CG3637, cortactin, cttn
 
 
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High impact information on Cortactin

 

Biological context of Cortactin

 

Anatomical context of Cortactin

 

Physical interactions of Cortactin

  • Proline-rich synapse-associated protein-1/cortactin binding protein 1 (ProSAP1/CortBP1) is a PDZ-domain protein highly enriched in the postsynaptic density [4].
 

Other interactions of Cortactin

  • We present evidence that Cortactin is one of the factors acting downstream of PVR and Src to stimulate F-actin accumulation [2].

References

  1. Cortactin associates with the cell-cell junction protein ZO-1 in both Drosophila and mouse. Katsube, T., Takahisa, M., Ueda, R., Hashimoto, N., Kobayashi, M., Togashi, S. J. Biol. Chem. (1998) [Pubmed]
  2. Cortactin modulates cell migration and ring canal morphogenesis during Drosophila oogenesis. Somogyi, K., Rørth, P. Mech. Dev. (2004) [Pubmed]
  3. Genomic organization, transcription start sites, and chromosomal location of the Drosophila cortactin gene. Katsube, T., Hashimoto, N., Sasaki, Y., Yamashita, A., Takahisa, M., Ueda, R., Togashi, S. Genes Genet. Syst. (2001) [Pubmed]
  4. Proline-rich synapse-associated protein-1/cortactin binding protein 1 (ProSAP1/CortBP1) is a PDZ-domain protein highly enriched in the postsynaptic density. Boeckers, T.M., Kreutz, M.R., Winter, C., Zuschratter, W., Smalla, K.H., Sanmarti-Vila, L., Wex, H., Langnaese, K., Bockmann, J., Garner, C.C., Gundelfinger, E.D. Ann. Anat. (2001) [Pubmed]
 
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