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Gene Review

EMCN  -  endomucin

Homo sapiens

Synonyms: EMCN2, Endomucin, Endomucin-2, Gastric cancer antigen Ga34, MUC-14, ...
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Disease relevance of EMCN


High impact information on EMCN


Biological context of EMCN

  • Human endomucin is predicted to encode a 261-aa, 27.5-kDa protein with a transmembrane sequence and multiple glycosylation sites [4].

Anatomical context of EMCN


Analytical, diagnostic and therapeutic context of EMCN


  1. A leukemia-enriched cDNA microarray platform identifies new transcripts with relevance to the biology of pediatric acute lymphoblastic leukemia. De Pittà, C., Tombolan, L., Campo Dell'Orto, M., Accordi, B., te Kronnie, G., Romualdi, C., Vitulo, N., Basso, G., Lanfranchi, G. Haematologica (2005) [Pubmed]
  2. Expression of endomucin, a novel endothelial sialomucin, in normal and diseased human skin. Kuhn, A., Brachtendorf, G., Kurth, F., Sonntag, M., Samulowitz, U., Metze, D., Vestweber, D. J. Invest. Dermatol. (2002) [Pubmed]
  3. Human endomucin: distribution pattern, expression on high endothelial venules, and decoration with the MECA-79 epitope. Samulowitz, U., Kuhn, A., Brachtendorf, G., Nawroth, R., Braun, A., Bankfalvi, A., Böcker, W., Vestweber, D. Am. J. Pathol. (2002) [Pubmed]
  4. Human endomucin is an endothelial marker. Liu, C., Shao, Z.M., Zhang, L., Beatty, P., Sartippour, M., Lane, T., Livingston, E., Nguyen, M. Biochem. Biophys. Res. Commun. (2001) [Pubmed]
  5. Endomucin, a sialomucin expressed in high endothelial venules, supports L-selectin-mediated rolling. Kanda, H., Tanaka, T., Matsumoto, M., Umemoto, E., Ebisuno, Y., Kinoshita, M., Noda, M., Kannagi, R., Hirata, T., Murai, T., Fukuda, M., Miyasaka, M. Int. Immunol. (2004) [Pubmed]
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