The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Lymphatic Vessels

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Lymphatic Vessels


High impact information on Lymphatic Vessels


Chemical compound and disease context of Lymphatic Vessels


Biological context of Lymphatic Vessels


Anatomical context of Lymphatic Vessels


Associations of Lymphatic Vessels with chemical compounds


Gene context of Lymphatic Vessels


Analytical, diagnostic and therapeutic context of Lymphatic Vessels


  1. Hyperplasia of lymphatic vessels in VEGF-C transgenic mice. Jeltsch, M., Kaipainen, A., Joukov, V., Meng, X., Lakso, M., Rauvala, H., Swartz, M., Fukumura, D., Jain, R.K., Alitalo, K. Science (1997) [Pubmed]
  2. Lymphangiogenic gene therapy with minimal blood vascular side effects. Saaristo, A., Veikkola, T., Tammela, T., Enholm, B., Karkkainen, M.J., Pajusola, K., Bueler, H., Ylä-Herttuala, S., Alitalo, K. J. Exp. Med. (2002) [Pubmed]
  3. Lymphatic endothelium and Kaposi's sarcoma spindle cells detected by antibodies against the vascular endothelial growth factor receptor-3. Jussila, L., Valtola, R., Partanen, T.A., Salven, P., Heikkilä, P., Matikainen, M.T., Renkonen, R., Kaipainen, A., Detmar, M., Tschachler, E., Alitalo, R., Alitalo, K. Cancer Res. (1998) [Pubmed]
  4. Angiosarcomas express mixed endothelial phenotypes of blood and lymphatic capillaries: podoplanin as a specific marker for lymphatic endothelium. Breiteneder-Geleff, S., Soleiman, A., Kowalski, H., Horvat, R., Amann, G., Kriehuber, E., Diem, K., Weninger, W., Tschachler, E., Alitalo, K., Kerjaschki, D. Am. J. Pathol. (1999) [Pubmed]
  5. Increased number of mature dendritic cells in Crohn's disease: evidence for a chemokine mediated retention mechanism. Middel, P., Raddatz, D., Gunawan, B., Haller, F., Radzun, H.J. Gut (2006) [Pubmed]
  6. The leukotriene C(4) transporter MRP1 regulates CCL19 (MIP-3beta, ELC)-dependent mobilization of dendritic cells to lymph nodes. Robbiani, D.F., Finch, R.A., Jäger, D., Muller, W.A., Sartorelli, A.C., Randolph, G.J. Cell (2000) [Pubmed]
  7. Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis. Petrova, T.V., Karpanen, T., Norrmén, C., Mellor, R., Tamakoshi, T., Finegold, D., Ferrell, R., Kerjaschki, D., Mortimer, P., Ylä-Herttuala, S., Miura, N., Alitalo, K. Nat. Med. (2004) [Pubmed]
  8. Cardiovascular failure in mouse embryos deficient in VEGF receptor-3. Dumont, D.J., Jussila, L., Taipale, J., Lymboussaki, A., Mustonen, T., Pajusola, K., Breitman, M., Alitalo, K. Science (1998) [Pubmed]
  9. Multiple sclerosis: presence of lymphatic capillaries and lymphoid tissue in the brain and spinal cord. Prineas, J.W. Science (1979) [Pubmed]
  10. PDZ interaction site in ephrinB2 is required for the remodeling of lymphatic vasculature. Mäkinen, T., Adams, R.H., Bailey, J., Lu, Q., Ziemiecki, A., Alitalo, K., Klein, R., Wilkinson, G.A. Genes Dev. (2005) [Pubmed]
  11. Suppression by nimesulide of bombesin-enhanced peritoneal metastasis of intestinal adenocarcinomas induced by azoxymethane in Wistar rats. Iishi, H., Tatsuta, M., Baba, M., Yano, H., Higashino, K., Mukai, M., Akedo, H. Clin. Exp. Metastasis (2003) [Pubmed]
  12. Mesenteric lymphatic vasomotion following hemorrhage and retransfusion in the rat. Higaki, A., Kawahara, M., Yuge, O., Fujii, K., Morio, M. Lymphology. (1990) [Pubmed]
  13. VEGF-C gene therapy augments postnatal lymphangiogenesis and ameliorates secondary lymphedema. Yoon, Y.S., Murayama, T., Gravereaux, E., Tkebuchava, T., Silver, M., Curry, C., Wecker, A., Kirchmair, R., Hu, C.S., Kearney, M., Ashare, A., Jackson, D.G., Kubo, H., Isner, J.M., Losordo, D.W. J. Clin. Invest. (2003) [Pubmed]
  14. Prox1 promotes lineage-specific expression of fibroblast growth factor (FGF) receptor-3 in lymphatic endothelium: a role for FGF signaling in lymphangiogenesis. Shin, J.W., Min, M., Larrieu-Lahargue, F., Canron, X., Kunstfeld, R., Nguyen, L., Henderson, J.E., Bikfalvi, A., Detmar, M., Hong, Y.K. Mol. Biol. Cell (2006) [Pubmed]
  15. Vascular endothelial growth factors C and D and their VEGFR-2 and 3 receptors in blood and lymphatic vessels in healthy and arthritic synovium. Paavonen, K., Mandelin, J., Partanen, T., Jussila, L., Li, T.F., Ristimaki, A., Alitalo, K., Konttinen, Y.T. J. Rheumatol. (2002) [Pubmed]
  16. The effect of external Ca2+ concentration on the contractility of bovine mesenteric lymphatics. McHale, N.G., Allen, J.M. Microvasc. Res. (1983) [Pubmed]
  17. Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation. Baluk, P., Tammela, T., Ator, E., Lyubynska, N., Achen, M.G., Hicklin, D.J., Jeltsch, M., Petrova, T.V., Pytowski, B., Stacker, S.A., Ylä-Herttuala, S., Jackson, D.G., Alitalo, K., McDonald, D.M. J. Clin. Invest. (2005) [Pubmed]
  18. Diversity, topographic differentiation, and positional memory in human fibroblasts. Chang, H.Y., Chi, J.T., Dudoit, S., Bondre, C., van de Rijn, M., Botstein, D., Brown, P.O. Proc. Natl. Acad. Sci. U.S.A. (2002) [Pubmed]
  19. A model for gene therapy of human hereditary lymphedema. Karkkainen, M.J., Saaristo, A., Jussila, L., Karila, K.A., Lawrence, E.C., Pajusola, K., Bueler, H., Eichmann, A., Kauppinen, R., Kettunen, M.I., Yla-Herttuala, S., Finegold, D.N., Ferrell, R.E., Alitalo, K. Proc. Natl. Acad. Sci. U.S.A. (2001) [Pubmed]
  20. Vascular endothelial growth factor D is dispensable for development of the lymphatic system. Baldwin, M.E., Halford, M.M., Roufail, S., Williams, R.A., Hibbs, M.L., Grail, D., Kubo, H., Stacker, S.A., Achen, M.G. Mol. Cell. Biol. (2005) [Pubmed]
  21. Interstitial insulin concentrations determine glucose uptake rates but not insulin resistance in lean and obese men. Castillo, C., Bogardus, C., Bergman, R., Thuillez, P., Lillioja, S. J. Clin. Invest. (1994) [Pubmed]
  22. Congenital hereditary lymphedema caused by a mutation that inactivates VEGFR3 tyrosine kinase. Irrthum, A., Karkkainen, M.J., Devriendt, K., Alitalo, K., Vikkula, M. Am. J. Hum. Genet. (2000) [Pubmed]
  23. Vasoactive intestinal peptide inhibitory innervation in bovine mesenteric lymphatics. A histochemical and pharmacological study. Ohhashi, T., Olschowka, J.A., Jacobowitz, D.M. Circ. Res. (1983) [Pubmed]
  24. Lymphatic obstruction in carcinomatous ascites. Feldman, G.B. Cancer Res. (1975) [Pubmed]
  25. Multiple forms of mouse vascular endothelial growth factor-D are generated by RNA splicing and proteolysis. Baldwin, M.E., Roufail, S., Halford, M.M., Alitalo, K., Stacker, S.A., Achen, M.G. J. Biol. Chem. (2001) [Pubmed]
  26. Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins. Karkkainen, M.J., Haiko, P., Sainio, K., Partanen, J., Taipale, J., Petrova, T.V., Jeltsch, M., Jackson, D.G., Talikka, M., Rauvala, H., Betsholtz, C., Alitalo, K. Nat. Immunol. (2004) [Pubmed]
  27. Isolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF-C/D receptor VEGFR-3. Mäkinen, T., Veikkola, T., Mustjoki, S., Karpanen, T., Catimel, B., Nice, E.C., Wise, L., Mercer, A., Kowalski, H., Kerjaschki, D., Stacker, S.A., Achen, M.G., Alitalo, K. EMBO J. (2001) [Pubmed]
  28. Mutations in the transcription factor gene SOX18 underlie recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia. Irrthum, A., Devriendt, K., Chitayat, D., Matthijs, G., Glade, C., Steijlen, P.M., Fryns, J.P., Van Steensel, M.A., Vikkula, M. Am. J. Hum. Genet. (2003) [Pubmed]
  29. Induction of cutaneous delayed-type hypersensitivity reactions in VEGF-A transgenic mice results in chronic skin inflammation associated with persistent lymphatic hyperplasia. Kunstfeld, R., Hirakawa, S., Hong, Y.K., Schacht, V., Lange-Asschenfeldt, B., Velasco, P., Lin, C., Fiebiger, E., Wei, X., Wu, Y., Hicklin, D., Bohlen, P., Detmar, M. Blood (2004) [Pubmed]
  30. Angiopoietin-1 promotes LYVE-1-positive lymphatic vessel formation. Morisada, T., Oike, Y., Yamada, Y., Urano, T., Akao, M., Kubota, Y., Maekawa, H., Kimura, Y., Ohmura, M., Miyamoto, T., Nozawa, S., Koh, G.Y., Alitalo, K., Suda, T. Blood (2005) [Pubmed]
  31. VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development. Kukk, E., Lymboussaki, A., Taira, S., Kaipainen, A., Jeltsch, M., Joukov, V., Alitalo, K. Development (1996) [Pubmed]
  32. Human endomucin: distribution pattern, expression on high endothelial venules, and decoration with the MECA-79 epitope. Samulowitz, U., Kuhn, A., Brachtendorf, G., Nawroth, R., Braun, A., Bankfalvi, A., Böcker, W., Vestweber, D. Am. J. Pathol. (2002) [Pubmed]
  33. The lymphatic drainage of the rat prostate and its status as an immunologically privileged site. Neaves, W.B., Billingham, R.E. Transplantation (1979) [Pubmed]
  34. Expression of endomucin, a novel endothelial sialomucin, in normal and diseased human skin. Kuhn, A., Brachtendorf, G., Kurth, F., Sonntag, M., Samulowitz, U., Metze, D., Vestweber, D. J. Invest. Dermatol. (2002) [Pubmed]
  35. Antibody guided lymphangiography in the staging of cervical cancer. Epenetos, A.A. Br. J. Cancer (1985) [Pubmed]
WikiGenes - Universities