The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Gene Review

PSY2  -  phytoene synthase

Solanum lycopersicum

 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of PSY2

  • A plasmid containing the PSY2 coding region under control of a bacterial promoter complements a Rhodobacter capsulatus phytoene synthase mutant, indicating that this gene has the capacity to encode an active enzyme [1].
  • Phytoene synthase from the bacterium Erwinia uredovora (crtB) has been overexpressed in tomato (Lycopersicon esculentum Mill. cv. Ailsa Craig) [2].
  • The antigen was prepared as a beta-galactosidase fusion protein by cloning a 1.13 kb fragment of Psy1 cDNA into pUR291, followed by transformation of E. coli [3].
 

High impact information on PSY2

 

Biological context of PSY2

 

Anatomical context of PSY2

 

Associations of PSY2 with chemical compounds

  • 6. Although phytoene synthase was functional in a monomeric state, under optimal native conditions it was associated with a large (at least 200 kDa) protein complex which contained other terpenoid enzymes such as isopentenyl diphosphate isomerase and geranylgeranyl diphosphate (GGPP) synthase [8].
 

Analytical, diagnostic and therapeutic context of PSY2

References

  1. cDNA cloning, expression during development, and genome mapping of PSY2, a second tomato gene encoding phytoene synthase. Bartley, G.E., Scolnik, P.A. J. Biol. Chem. (1993) [Pubmed]
  2. Evaluation of transgenic tomato plants expressing an additional phytoene synthase in a fruit-specific manner. Fraser, P.D., Romer, S., Shipton, C.A., Mills, P.B., Kiano, J.W., Misawa, N., Drake, R.G., Schuch, W., Bramley, P.M. Proc. Natl. Acad. Sci. U.S.A. (2002) [Pubmed]
  3. Production and characterisation of monoclonal antibodies to phytoene synthase of Lycopersicon esculentum. Fraser, P.D., Misawa, N., Sandmann, G., Johnson, J., Schuch, W., Bramley, P.M. Phytochemistry (1998) [Pubmed]
  4. Candidate gene analysis of organ pigmentation loci in the Solanaceae. Thorup, T.A., Tanyolac, B., Livingstone, K.D., Popovsky, S., Paran, I., Jahn, M. Proc. Natl. Acad. Sci. U.S.A. (2000) [Pubmed]
  5. A tomato gene expressed during fruit ripening encodes an enzyme of the carotenoid biosynthesis pathway. Bartley, G.E., Viitanen, P.V., Bacot, K.O., Scolnik, P.A. J. Biol. Chem. (1992) [Pubmed]
  6. Why is golden rice golden (yellow) instead of red? Schaub, P., Al-Babili, S., Drake, R., Beyer, P. Plant Physiol. (2005) [Pubmed]
  7. Increases in cell elongation, plastid compartment size and phytoene synthase activity underlie the phenotype of the high pigment-1 mutant of tomato. Cookson, P.J., Kiano, J.W., Shipton, C.A., Fraser, P.D., Romer, S., Schuch, W., Bramley, P.M., Pyke, K.A. Planta (2003) [Pubmed]
  8. Phytoene synthase from tomato (Lycopersicon esculentum) chloroplasts--partial purification and biochemical properties. Fraser, P.D., Schuch, W., Bramley, P.M. Planta (2000) [Pubmed]
 
WikiGenes - Universities