Disease relevance of RASIP1

• Pathogenesis of myiasis due to the muscid fly Philornis deceptivus in nestling pearly-eyed thrashers (Margarops fuscatus) in the Luquillo Rain Forest, Puerto Rico was investigated [1].
• The majority were young adults with no ocular complications suggesting the Rain Forest type of African onchocerciasis [2].
• In this paper we will attempt to answer the question, "What is Yellow Rain?", summarize some of the massive data on microtoxins and mycotoxicoses, discuss the toxicology of the trichothecenes, give a brief historical perspective on chemical warfare, and touch on some of the political implications of these developments [3].

High impact information on RASIP1

• Neurobiology. Rain Man's revelations [4].
• We identified Bcr as a ligand for the PDZ domain of the cell junction and Ras-interacting protein AF-6 [5].
• A novel Ras-interacting protein required for chemotaxis and cyclic adenosine monophosphate signal relay in Dictyostelium [6].
• (b) "Rain" pattern: Flow cytometry methods count slightly damaged leukocytes not removed during leukoreduction [7].
• In 1997 the Flemish Environmental Agency (FEA) started a monitoring program "Pesticides in Rain in Flanders, Belgium". The original purpose of the monitoring program was to examine the possible occurrence of dichlorvos in rainwater and subsequent deposition [8].

Biological context of RASIP1

• Global warming. Rain might be leading carbon sink factor [9].

Analytical, diagnostic and therapeutic context of RASIP1

• The protein-protein interaction map of H. pylori, which is based on a high-throughput two-hybrid screen (Rain et al., 2001. Nature 409, 211-215) indicated a protein-protein interaction between the gene product of ORF hp137 and both the histidine kinase HP244 and the flagellar hook protein HP908 [10].

References