Gene Review:
Ube4b - ubiquitination factor E4B
Mus musculus
Synonyms:
4930551I19Rik, 4933406G05Rik, AU014668, D4Bwg0973e, UFD2, ...
- Mammalian E4 is required for cardiac development and maintenance of the nervous system. Kaneko-Oshikawa, C., Nakagawa, T., Yamada, M., Yoshikawa, H., Matsumoto, M., Yada, M., Hatakeyama, S., Nakayama, K., Nakayama, K.I. Mol. Cell. Biol. (2005)
- A Ufd2/D4Cole1e chimeric protein and overexpression of Rbp7 in the slow Wallerian degeneration (WldS) mouse. Conforti, L., Tarlton, A., Mack, T.G., Mi, W., Buckmaster, E.A., Wagner, D., Perry, V.H., Coleman, M.P. Proc. Natl. Acad. Sci. U.S.A. (2000)
- The neuroprotective WldS gene regulates expression of PTTG1 and erythroid differentiation regulator 1-like gene in mice and human cells. Gillingwater, T.H., Wishart, T.M., Chen, P.E., Haley, J.E., Robertson, K., MacDonald, S.H., Middleton, S., Wawrowski, K., Shipston, M.J., Melmed, S., Wyllie, D.J., Skehel, P.A., Coleman, M.P., Ribchester, R.R. Hum. Mol. Genet. (2006)
- Characterization of the mouse gene for the U-box-type ubiquitin ligase UFD2a. Kaneko, C., Hatakeyama, S., Matsumoto, M., Yada, M., Nakayama, K., Nakayama, K.I. Biochem. Biophys. Res. Commun. (2003)
- The slow Wallerian degeneration protein, WldS, binds directly to VCP/p97 and partially redistributes it within the nucleus. Laser, H., Conforti, L., Morreale, G., Mack, T.G., Heyer, M., Haley, J.E., Wishart, T.M., Beirowski, B., Walker, S.A., Haase, G., Celik, A., Adalbert, R., Wagner, D., Grumme, D., Ribchester, R.R., Plomann, M., Coleman, M.P. Mol. Biol. Cell (2006)
- Human homologue of a gene mutated in the slow Wallerian degeneration (C57BL/Wld(s)) mouse. Fernando, F.S., Conforti, L., Tosi, S., Smith, A.D., Coleman, M.P. Gene (2002)
- Age-dependent synapse withdrawal at axotomised neuromuscular junctions in Wld(s) mutant and Ube4b/Nmnat transgenic mice. Gillingwater, T.H., Thomson, D., Mack, T.G., Soffin, E.M., Mattison, R.J., Coleman, M.P., Ribchester, R.R. J. Physiol. (Lond.) (2002)
- A rat model of slow Wallerian degeneration (WldS) with improved preservation of neuromuscular synapses. Adalbert, R., Gillingwater, T.H., Haley, J.E., Bridge, K., Beirowski, B., Berek, L., Wagner, D., Grumme, D., Thomson, D., Celik, A., Addicks, K., Ribchester, R.R., Coleman, M.P. Eur. J. Neurosci. (2005)
- The human homologue of the yeast polyubiquitination factor Ufd2p is cleaved by caspase 6 and granzyme B during apoptosis. Mahoney, J.A., Odin, J.A., White, S.M., Shaffer, D., Koff, A., Casciola-Rosen, L., Rosen, A. Biochem. J. (2002)
- The cellular distribution of the Wld s chimeric protein and its constituent proteins in the CNS. Fang, C., Bernardes-Silva, M., Coleman, M.P., Perry, V.H. Neuroscience (2005)