Gene Review:
SNRPC - small nuclear ribonucleoprotein polypeptide C
Homo sapiens
Synonyms:
U1 small nuclear ribonucleoprotein C, U1 snRNP C, U1-C, U1C, Yhc1
- B cell epitope on the U1 snRNP-C autoantigen contains a sequence similar to that of the herpes simplex virus protein. Misaki, Y., Yamamoto, K., Yanagi, K., Miura, H., Ichijo, H., Kato, T., Mato, T., Welling-Wester, S., Nishioka, K., Ito, K. Eur. J. Immunol. (1993)
- Comparison of two different methods using overlapping synthetic peptides for localizing linear B cell epitopes in the U1 snRNP-C autoantigen. Halimi, H., Dumortier, H., Briand, J.P., Muller, S. J. Immunol. Methods (1996)
- The splicing regulator TIA-1 interacts with U1-C to promote U1 snRNP recruitment to 5' splice sites. Förch, P., Puig, O., Martínez, C., Séraphin, B., Valcárcel, J. EMBO J. (2002)
- Identification and characterization of a yeast homolog of U1 snRNP-specific protein C. Tang, J., Abovich, N., Fleming, M.L., Seraphin, B., Rosbash, M. EMBO J. (1997)
- The association of the U1-specific 70K and C proteins with U1 snRNPs is mediated in part by common U snRNP proteins. Nelissen, R.L., Will, C.L., van Venrooij, W.J., Lührmann, R. EMBO J. (1994)
- The splicing factor U1C represses EWS/FLI-mediated transactivation. Knoop, L.L., Baker, S.J. J. Biol. Chem. (2000)
- Identification of a putative oocyte-specific small nuclear ribonucleoprotein polypeptide C in gibel carp. Wang, H.Y., Zhou, L., Gui, J.F. Comp. Biochem. Physiol. B, Biochem. Mol. Biol. (2007)
- At least three linear regions but not the zinc-finger domain of U1C protein are exposed at the surface of the protein in solution and on the human spliceosomal U1 snRNP particle. Dumortier, H., Klein Gunnewiek, J., Roussel, J.P., van Aarssen, Y., Briand, J.P., van Venrooij, W.J., Muller, S. Nucleic Acids Res. (1998)
- Homodimerization of the human U1 snRNP-specific protein C. Gunnewiek, J.M., van Aarssen, Y., Wassenaar, R., Legrain, P., van Venrooij, W.J., Nelissen, R.L. Nucleic Acids Res. (1995)
- Human monoclonal autoantibody fragments from combinatorial antibody libraries directed to the U1snRNP associated U1C protein; epitope mapping, immunolocalization and V-gene usage. Hoet, R.M., Raats, J.M., de Wildt, R., Dumortier, H., Muller, S., van den Hoogen, F., van Venrooij, W.J. Mol. Immunol. (1998)
- Involvement of U1 small nuclear ribonucleoproteins (snRNP) in 5' splice site-U1 snRNP interaction. Rossi, F., Forné, T., Antoine, E., Tazi, J., Brunel, C., Cathala, G. J. Biol. Chem. (1996)
- Nuclear accumulation of the U1 snRNP-specific protein C is due to diffusion and retention in the nucleus. Klein Gunnewiek, J.M., van Aarssen, Y., van der Kemp, A., Nelissen, R., Pruijn, G.J., van Venrooij, W.J. Exp. Cell Res. (1997)
- Autoantibodies that stabilize U1snRNP are a significant component of human autoantibodies to snRNP and delay proteolysis of sm antigens in vitro. Satoh, M., Akaogi, J., Kuroda, Y., Nacionales, D.C., Yoshida, H., Yamasaki, Y., Reeves, W.H. J. Rheumatol. (2004)
- HLA class II genes and antibodies against recombinant U1-nRNP proteins in patients with systemic lupus erythematosus. SLE Study Group. Yao, Z., Seelig, H.P., Ehrfeld, H., Renz, M., Hartung, K., Deicher, H., Keller, E., Nevinny-Stickel, C., Albert, E.D. Rheumatol. Int. (1994)