Disease relevance of Goldfish

• We now report that a parkinsonian syndrome can be elicited in the common goldfish (Carassius auratus) by a single dose of MPTP [1].
• This study was conducted to determine whether prostaglandin f2 alpha (PGF)-induced spawning behavior in female goldfish (Carassius auratus) is influenced by sex steroids or by the stage of ovarian development (assessed by gonadosomatic index (GSI), ovary weight expressed as a percentage of body weight) [2].
• Earlier studies identified some important fish IFN system genes from IFN-induced CAB cells (crucian carp Carassius auratus L. embryonic blastulae cells) after treatment with UV-inactivated GCHV (grass carp hemorrhage virus) [3].
• Effect of ascorbic acid on biotransformation and modification of the toxicity of mercurials in goldfish (Carassius auratus) [4].

Psychiatry related information on Goldfish

• The role of telencephalic NMDA receptors in avoidance learning in goldfish (Carassius auratus) [5].
• Central administration of melanin-concentrating hormone (MCH) suppresses food intake, but not locomotor activity, in the goldfish, Carassius auratus [6].
• Effects of actinomycin D on brain RNA synthesis and discrimination learning in the goldfish (Carassius auratus) [7].

High impact information on Goldfish

• Together with the previously cloned Carassius auratus (goldfish) gene they form a separate group of photolyase genes [8].
• In the goldfish (Carassius auratus) the two endogenous forms of gonadotropin-releasing hormone (GnRH), namely chicken GnRH II ([His5, Trp7,Tyr8]GnRH) and salmon GnRH ([Trp7,Leu8]GnRH), stimulate the release of both gonadotropins and growth hormone from the pituitary [9].
• Two gonadotropin-releasing hormone receptor subtypes with distinct ligand selectivity and differential distribution in brain and pituitary in the goldfish (Carassius auratus) [9].
• Microtubule staining patterns can be visualized within cells in situ on the surface of fish scales from the squirrel fish, Holocentrus ascensionis, and the common goldfish, Carassius auratus, after incubation with antibodies to sea urchin tubulin and fluorescein-labeled goat antibodies to rabbit immunoglobulin G [10].
• A novel hematopoietic granulin induces proliferation of goldfish (Carassius auratus L.) macrophages [11].

Chemical compound and disease context of Goldfish

• Uptake and toxicity of toxaphene to cell cultures derived from goldfish (Carassius auratus) [12].
• Acute toxicity of nitrofurazone to channel catfish, Ictalurus punctatus, and goldfish, Carassius auratus [13].
• Acute toxicity (96-h LC50) of malathion was tested using five species of freshwater fish, namely, topmouth gudgeon (Pseudorasbora parva), goldfish (Carassius auratus), nile tilapia (Tilapia nilotica), mosquitofish (Gambusia affinis), and rainbow trout (Salmo gairdneri) [14].

Biological context of Goldfish

• Melatonin signal transduction in the goldfish, Carassius auratus [15].
• To understand how the blastema is formed and how this growth situation is set up, we investigated cell proliferation patterns in the regenerating fin of the goldfish Carassius auratus from the time of amputation to that of blastema formation by using proliferating cell nuclear antigen immunostaining and bromodeoxyuridine labeling [16].
• Daily and circadian variations in melatonin binding sites in the brain of goldfish (Carassius auratus) were examined by radioreceptor assay [17].
• Influence of forskolin and carbachol on intestinal absorption of horseradish peroxidase in the goldfish (Carassius auratus) [18].
• Evidence for a gonadotropin-releasing hormone binding protein in goldfish (Carassius auratus) serum [19].

Anatomical context of Goldfish

• Responses of solitary retinal horizontal cells from Carassius auratus to L-glutamate and related amino acids [20].
• Phosphorous spectra of ATP and creatine phosphate (PCr) in solution and goldfish (Carassius auratus) skeletal muscle demonstrate the effectiveness of homonuclear decoupling in improving the effective signal-to-noise ratio of ATP [21].
• In-vivo evaluation of dopamine receptor-mediated inhibition of gonadotrophin secretion from the pituitary gland of the goldfish, Carassius auratus [22].
• In goldfish (Carassius auratus), 17alpha,20beta-DP induces oocyte maturation by stimulating the de novo synthesis of cyclin B, a regulatory subunit of maturation-promoting factor (MPF) [23].
• Nitric oxide synthase in the peripheral nervous system of the goldfish, Carassius auratus [24].

Associations of Goldfish with chemical compounds

• Generation and reception of melatonin signals in the goldfish, Carassius auratus, are reviewed [15].
• Characterization of D1 receptors mediating dopamine-stimulated growth hormone release from pituitary cells of the goldfish, Carassius auratus [25].
• Effects of L-glutamate on the anomalous rectifier potassium current in horizontal cells of Carassius auratus retina [26].
• Experiments were carried out on the goldfish Carassius auratus to determine if androgen receptors are present in teleost brain and whether their physicochemical properties reflect elevated aromatase [27].
• The release of gamma-aminobutyric acid from horizontal cells of the goldfish (Carassius auratus) retina [28].

Gene context of Goldfish

• The brain of many teleost fish species, including the goldfish Carassius auratus, expresses exceptionally high levels of cytochrome P450 aromatase (estrogen synthetase) [29].
• Characterization of the leukemia inhibitory factor receptor in the goldfish (Carassius auratus) [30].
• Molecular cloning of an estrogen receptor beta subtype from the goldfish, Carassius auratus [29].
• Interactions between orexin A, NPY and galanin in the control of food intake of the goldfish, Carassius auratus [31].
• Appetite-suppressing effects of urotensin I and corticotropin-releasing hormone in goldfish (Carassius auratus) [32].

Analytical, diagnostic and therapeutic context of Goldfish

• The topographical distribution of estradiol-concentrating cells in the brain of male and female teleost, Carassius auratus, was determined by autoradiography, after injection of 3H estradiol-17beta [33].
• We show here that hemocytes and leukocytes with phagocytic activity from both invertebrates (Planorbarius corneus, Viviparus ater) and vertebrates (Carassius auratus, Rana esculenta) express pro-opiomelanocortin (POMC) mRNA, as assessed by in situ hybridization with a digoxigenin-labeled human DNA probe [34].
• In goldfish (Carassius auratus), two distinct forms of gonadotropin-releasing hormone (GnRH), namely, salmon GnRH (sGnRH) and chicken GnRH-II (cGnRH-II), have been identified in the brain using chromatographic, immunological, and molecular cloning approaches [35].
• From neurointermediate lobe (NIL) extracts of two species of Cyprinidae, Carassius auratus and Cyprinus carpio, several peptides were separated by high-performance liquid chromatography (HPLC) on a C18 muBondapak column eluted with a methanol/acetic acid/triethylamine mixture [36].
• Three monoclonal antibodies were used to examine with immunocytochemistry the distribution of the glycine receptors and the related 93kd polypeptide in the adult goldfish brain (Carassius auratus) [37].

References