The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Gene Review

PF10_0343  -  S-antigen

Plasmodium falciparum 3D7

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on PF10_0343


Biological context of PF10_0343


Anatomical context of PF10_0343

  • The S-antigen of Plasmodium falciparum is a highly diverse heat stable protein that is located in the parasitophorous vacuole of the mature asexual intraerythrocytic parasite [9].
  • Cross-sectional and longitudinal village-based studies of the transmission dynamics of an S-antigen serotype of the asexual erythrocyte stages of Plasmodium falciparum have been carried out in Madang, Papua New Guinea (PNG) [10].

Associations of PF10_0343 with chemical compounds


Other interactions of PF10_0343

  • We describe the use of the Mantel test for assessing clustering of individual parasite alleles at the household level, and demonstrate low-level clustering of MSP-1 and MSP-2 alleles and S-antigen sequence types, at the end of a long period of low transmission [7].
  • The glycophorin-binding protein, the histidine-rich protein II, the S-antigen, the heat shock protein 70, the ring-infected erythrocyte surface antigen, and the apical membrane antigen-1 were also shown serologically to be present in the mixture of exoantigens [13].

Analytical, diagnostic and therapeutic context of PF10_0343


  1. Conserved sequences flank variable tandem repeats in two S-antigen genes of Plasmodium falciparum. Cowman, A.F., Saint, R.B., Coppel, R.L., Brown, G.V., Anders, R.F., Kemp, D.J. Cell (1985) [Pubmed]
  2. Changes in repeat number, sequence, and reading frame in S-antigen genes of Plasmodium falciparum. Saint, R.B., Coppel, R.L., Cowman, A.F., Brown, G.V., Shi, P.T., Barzaga, N., Kemp, D.J., Anders, R.F. Mol. Cell. Biol. (1987) [Pubmed]
  3. Anchoring a secreted plasmodium antigen on the surface of recombinant vaccinia virus-infected cells increases its immunogenicity. Langford, C.J., Edwards, S.J., Smith, G.L., Mitchell, G.F., Moss, B., Kemp, D.J., Anders, R.F. Mol. Cell. Biol. (1986) [Pubmed]
  4. Heteroduplex stabilities in highly repetitive DNA. An hypothesis for the polymorphism of Plasmodium parasite antigenic response. Dodin, G. FEBS Lett. (1986) [Pubmed]
  5. In vivo and in vitro derived Palo Alto lines of Plasmodium falciparum are genetically unrelated. Fandeur, T., Bonnefoy, S., Mercereau-Puijalon, O. Mol. Biochem. Parasitol. (1991) [Pubmed]
  6. Antigenic diversity and size diversity of Plasmodium falciparum antigens in isolates from Gambian patients. I. S-antigens. Howard, R.J., Panton, L.J., Marsh, K., Ling, I.T., Winchell, E.J., Wilson, R.J. Parasite Immunol. (1986) [Pubmed]
  7. Limited spatial clustering of individual Plasmodium falciparum alleles in field isolates from coastal Kenya. Kyes, S., Harding, R., Black, G., Craig, A., Peshu, N., Newbold, C., Marsh, K. Am. J. Trop. Med. Hyg. (1997) [Pubmed]
  8. Molecular variation in Plasmodium falciparum: polymorphic antigens of asexual erythrocytic stages. Anders, R.F., McColl, D.J., Coppel, R.L. Acta Trop. (1993) [Pubmed]
  9. A fourth family of the Plasmodium falciparum S-antigen. Bickle, Q., Coppel, R.L. Mol. Biochem. Parasitol. (1992) [Pubmed]
  10. Small area variation in prevalence of an S-antigen serotype of Plasmodium falciparum in villages of Madang, Papua New Guinea. Forsyth, K.P., Anders, R.F., Cattani, J.A., Alpers, M.P. Am. J. Trop. Med. Hyg. (1989) [Pubmed]
  11. An S antigen gene from Plasmodium falciparum contains a novel repetitive sequence. Nicholls, S.C., Hillman, Y., Lockyer, M.J., Odink, K.G., Holder, A.A. Mol. Biochem. Parasitol. (1988) [Pubmed]
  12. Chemical crosslinking of Plasmodium falciparum glycoprotein, Pf200 (190-205 kDa), to the S-antigen at the merozoite surface. Perkins, M.E., Rocco, L.J. Exp. Parasitol. (1990) [Pubmed]
  13. Serine-stretch protein (SERP) of Plasmodium falciparum corresponds to the exoantigen Ag2, a target of antibodies associated with protection against malaria. Jakobsen, P.H., Hundt, E., Hansen, M.B., Knapp, B. APMIS (1994) [Pubmed]
  14. Characterization of an S antigen synthesized by several isolates of Plasmodium falciparum. Anders, R.F., Brown, G.V., Edwards, A. Proc. Natl. Acad. Sci. U.S.A. (1983) [Pubmed]
  15. Metabolic labelling and characterisation of S-antigens, the heat-stable, strain-specific antigens of Plasmodium falciparum. Winchell, E.J., Ling, I.T., Wilson, R.J. Mol. Biochem. Parasitol. (1984) [Pubmed]
  16. S-antigen localization in the erythrocytic stages of Plasmodium falciparum. Culvenor, J.G., Crewther, P.E. J. Protozool. (1990) [Pubmed]
WikiGenes - Universities