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Gene Review

RBR1  -  Retinoblastoma-related protein 1

Arabidopsis thaliana

Synonyms: ATRBR1, RB, RB1, RBR, RETINOBLASTOMA 1, ...
 
 
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Disease relevance of RBR1

 

High impact information on RBR1

 

Biological context of RBR1

 

Anatomical context of RBR1

  • Arabidopsis contains a single RBR gene, and its loss of function precludes gamete formation and early development [6].
 

Associations of RBR1 with chemical compounds

  • Aphidicolin-arrested but not roscovitine-arrested cells contain a PSTAIRE-type CDK that binds to and phosphorylates RBR [10].
 

Other interactions of RBR1

References

  1. The Nanovirus-Encoded Clink Protein Affects Plant Cell Cycle Regulation through Interaction with the Retinoblastoma-Related Protein. Lageix, S., Catrice, O., Deragon, J.M., Gronenborn, B., Pélissier, T., Ramírez, B.C. J. Virol. (2007) [Pubmed]
  2. The RETINOBLASTOMA-RELATED gene regulates stem cell maintenance in Arabidopsis roots. Wildwater, M., Campilho, A., Perez-Perez, J.M., Heidstra, R., Blilou, I., Korthout, H., Chatterjee, J., Mariconti, L., Gruissem, W., Scheres, B. Cell (2005) [Pubmed]
  3. Regulation of flowering time by FVE, a retinoblastoma-associated protein. Ausín, I., Alonso-Blanco, C., Jarillo, J.A., Ruiz-García, L., Martínez-Zapater, J.M. Nat. Genet. (2004) [Pubmed]
  4. The female gametophyte and the endosperm control cell proliferation and differentiation of the seed coat in Arabidopsis. Ingouff, M., Jullien, P.E., Berger, F. Plant Cell (2006) [Pubmed]
  5. Plant retinoblastoma homologues control nuclear proliferation in the female gametophyte. Ebel, C., Mariconti, L., Gruissem, W. Nature (2004) [Pubmed]
  6. Cell type-specific role of the retinoblastoma/E2F pathway during Arabidopsis leaf development. Desvoyes, B., Ramirez-Parra, E., Xie, Q., Chua, N.H., Gutierrez, C. Plant Physiol. (2006) [Pubmed]
  7. Arabidopsis E2Fc functions in cell division and is degraded by the ubiquitin-SCF(AtSKP2) pathway in response to light. del Pozo, J.C., Boniotti, M.B., Gutierrez, C. Plant Cell (2002) [Pubmed]
  8. G(1) to S transition: more than a cell cycle engine switch. Gutierrez, C., Ramirez-Parra, E., Castellano, M.M., del Pozo, J.C. Curr. Opin. Plant Biol. (2002) [Pubmed]
  9. Activation of an alfalfa cyclin-dependent kinase inhibitor by calmodulin-like domain protein kinase. Pettkó-Szandtner, A., Mészáros, T., Horváth, G.V., Bakó, L., Csordás-Tóth, E., Blastyák, A., Zhiponova, M., Miskolczi, P., Dudits, D. Plant J. (2006) [Pubmed]
  10. A cell-cycle-regulated kinase activity phosphorylates plant retinoblastoma protein and contains, in Arabidopsis, a CDKA/cyclin D complex. Boniotti, M.B., Gutierrez, C. Plant J. (2001) [Pubmed]
  11. The D-type alfalfa cyclin gene cycMs4 complements G1 cyclin-deficient yeast and is induced in the G1 phase of the cell cycle. Dahl, M., Meskiene, I., Bögre, L., Ha, D.T., Swoboda, I., Hubmann, R., Hirt, H., Heberle-Bors, E. Plant Cell (1995) [Pubmed]
 
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