Gene Review:
NT5C1A - 5'-nucleotidase, cytosolic IA
Homo sapiens
Synonyms:
CN-I, CN-IA, CN1, CN1A, CNI, ...
Picher,
Burch,
Hirsh,
Spychala,
Boucher,
Sala-Newby,
Newby,
Hanisch,
Hellsten,
Zierz,
Sala-Newby,
Freeman,
Skladanowski,
Newby,
- Enforced expression of cytosolic 5'-nucleotidase I confers resistance to nucleoside analogues in vitro but systemic chemotherapy toxicity precludes in vivo selection. Gray, T., Morrey, E.L., Gangadharan, B., Sumter, T.F., Spychala, J., Archer, D.R., Spencer, H.T. Cancer Chemother. Pharmacol. (2006)
- Adenosine as a metabolic regulator of tissue function: production of adenosine by cytoplasmic 5'-nucleotidases. Borowiec, A., Lechward, K., Tkacz-Stachowska, K., Składanowski, A.C. Acta Biochim. Pol. (2006)
- Ecto 5'-nucleotidase and nonspecific alkaline phosphatase. Two AMP-hydrolyzing ectoenzymes with distinct roles in human airways. Picher, M., Burch, L.H., Hirsh, A.J., Spychala, J., Boucher, R.C. J. Biol. Chem. (2003)
- Human cytosolic 5'-nucleotidase I: characterization and role in nucleoside analog resistance. Hunsucker, S.A., Spychala, J., Mitchell, B.S. J. Biol. Chem. (2001)
- Distinct roles for recombinant cytosolic 5'-nucleotidase-I and -II in AMP and IMP catabolism in COS-7 and H9c2 rat myoblast cell lines. Sala-Newby, G.B., Freeman, N.V., Skladanowski, A.C., Newby, A.C. J. Biol. Chem. (2000)
- Ecto- and cytosolic 5'-nucleotidases in normal and AMP deaminase-deficient human skeletal muscle. Hanisch, F., Hellsten, Y., Zierz, S. Biol. Chem. (2006)
- Cloning of a mouse cytosolic 5'-nucleotidase-I identifies a new gene related to human autoimmune infertility-related protein. Sala-Newby, G.B., Newby, A.C. Biochim. Biophys. Acta (2001)