Gene Review:
MDJ1 - Mdj1p
Saccharomyces cerevisiae S288c
Synonyms:
DnaJ homolog 1, mitochondrial, YFL016C
- Two distinct mechanisms operate in the reactivation of heat-denatured proteins by the mitochondrial Hsp70/Mdj1p/Yge1p chaperone system. Kubo, Y., Tsunehiro, T., Nishikawa, S., Nakai, M., Ikeda, E., Toh-e, A., Morishima, N., Shibata, T., Endo, T. J. Mol. Biol. (1999)
- Structure-function analyses of the Ssc1p, Mdj1p, and Mge1p Saccharomyces cerevisiae mitochondrial proteins in Escherichia coli. Deloche, O., Kelley, W.L., Georgopoulos, C. J. Bacteriol. (1997)
- Mdj1p, a novel chaperone of the DnaJ family, is involved in mitochondrial biogenesis and protein folding. Rowley, N., Prip-Buus, C., Westermann, B., Brown, C., Schwarz, E., Barrell, B., Neupert, W. Cell (1994)
- A yeast DnaJ homologue, Scj1p, can function in the endoplasmic reticulum with BiP/Kar2p via a conserved domain that specifies interactions with Hsp70s. Schlenstedt, G., Harris, S., Risse, B., Lill, R., Silver, P.A. J. Cell Biol. (1995)
- Dual role of the mitochondrial chaperone Mdj1p in inheritance of mitochondrial DNA in yeast. Duchniewicz, M., Germaniuk, A., Westermann, B., Neupert, W., Schwarz, E., Marszalek, J. Mol. Cell. Biol. (1999)
- The PbMDJ1 gene belongs to a conserved MDJ1/LON locus in thermodimorphic pathogenic fungi and encodes a heat shock protein that localizes to both the mitochondria and cell wall of Paracoccidioides brasiliensis. Batista, W.L., Matsuo, A.L., Ganiko, L., Barros, T.F., Veiga, T.R., Freymüller, E., Puccia, R. Eukaryotic Cell (2006)
- Role of the mitochondrial DnaJ homolog Mdj1p as a chaperone for mitochondrially synthesized and imported proteins. Westermann, B., Gaume, B., Herrmann, J.M., Neupert, W., Schwarz, E. Mol. Cell. Biol. (1996)
- A novel non-conventional heat shock element regulates expression of MDJ1 encoding a DnaJ homolog in Saccharomyces cerevisiae. Tachibana, T., Astumi, S., Shioda, R., Ueno, M., Uritani, M., Ushimaru, T. J. Biol. Chem. (2002)
- Gene regulation in response to overexpression of cytochrome P450 and proliferation of the endoplasmic reticulum in Saccharomyces cerevisiae. Zimmer, T., Ogura, A., Takewaka, T., Zimmer, R.M., Ohta, A., Takagi, M. Biosci. Biotechnol. Biochem. (2000)
- Importance of two ATP-binding sites for oligomerization, ATPase activity and chaperone function of mitochondrial Hsp78 protein. Krzewska, J., Konopa, G., Liberek, K. J. Mol. Biol. (2001)
- Purification and biochemical properties of Saccharomyces cerevisiae's Mge1p, the mitochondrial cochaperone of Ssc1p. Deloche, O., Georgopoulos, C. J. Biol. Chem. (1996)
- The two mitochondrial heat shock proteins 70, Ssc1 and Ssq1, compete for the cochaperone Mge1. Schmidt, S., Strub, A., Röttgers, K., Zufall, N., Voos, W. J. Mol. Biol. (2001)
- The mitochondrial proteins Ssq1 and Jac1 are required for the assembly of iron sulfur clusters in mitochondria. Lutz, T., Westermann, B., Neupert, W., Herrmann, J.M. J. Mol. Biol. (2001)