Gene Review:
DFR1 - dihydrofolate reductase
Saccharomyces cerevisiae S288c
Synonyms:
Dihydrofolate reductase, O5231, YOR236W
- Molecular characterization of the Saccharomyces cerevisiae dihydrofolate reductase gene (DFR1). Lagosky, P.A., Taylor, G.R., Haynes, R.H. Nucleic Acids Res. (1987)
- In vitro generation of novel pyrimethamine resistance mutations in the Toxoplasma gondii dihydrofolate reductase. Reynolds, M.G., Oh, J., Roos, D.S. Antimicrob. Agents Chemother. (2001)
- Identification of the optimal third generation antifolate against P. falciparum and P. vivax. Hunt, S.Y., Detering, C., Varani, G., Jacobus, D.P., Schiehser, G.A., Shieh, H.M., Nevchas, I., Terpinski, J., Sibley, C.H. Mol. Biochem. Parasitol. (2005)
- Mdj1p, a novel chaperone of the DnaJ family, is involved in mitochondrial biogenesis and protein folding. Rowley, N., Prip-Buus, C., Westermann, B., Brown, C., Schwarz, E., Barrell, B., Neupert, W. Cell (1994)
- Cytochromes c1 and b2 are sorted to the intermembrane space of yeast mitochondria by a stop-transfer mechanism. Glick, B.S., Brandt, A., Cunningham, K., Müller, S., Hallberg, R.L., Schatz, G. Cell (1992)
- Gene targeting in normal and amplified cell lines. Zheng, H., Wilson, J.H. Nature (1990)
- Heat-inducible degron: a method for constructing temperature-sensitive mutants. Dohmen, R.J., Wu, P., Varshavsky, A. Science (1994)
- Prevention of protein denaturation under heat stress by the chaperonin Hsp60. Martin, J., Horwich, A.L., Hartl, F.U. Science (1992)
- Mapping and sequencing of the dihydrofolate reductase gene (DFR1) of Saccharomyces cerevisiae. Barclay, B.J., Huang, T., Nagel, M.G., Misener, V.L., Game, J.C., Wahl, G.M. Gene (1988)
- Transcription of genes encoding enzymes involved in DNA synthesis during the cell cycle of Saccharomyces cerevisiae. McIntosh, E.M., Gadsden, M.H., Haynes, R.H. Mol. Gen. Genet. (1986)
- Amplification of a circular episome carrying an inverted repeat of the DFR1 locus and adjacent autonomously replicating sequence element of Saccharomyces cerevisiae. Huang, T., Campbell, J.L. J. Biol. Chem. (1995)
- An internal region of the peroxisomal membrane protein PMP47 is essential for sorting to peroxisomes. McCammon, M.T., McNew, J.A., Willy, P.J., Goodman, J.M. J. Cell Biol. (1994)
- Import of a DHFR hybrid protein into glycosomes in vivo is not inhibited by the folate-analogue aminopterin. Häusler, T., Stierhof, Y.D., Wirtz, E., Clayton, C. J. Cell Biol. (1996)
- Protein folding causes an arrest of preprotein translocation into mitochondria in vivo. Wienhues, U., Becker, K., Schleyer, M., Guiard, B., Tropschug, M., Horwich, A.L., Pfanner, N., Neupert, W. J. Cell Biol. (1991)
- The phenotype of a dihydrofolate reductase mutant of Saccharomyces cerevisiae. Huang, T., Barclay, B.J., Kalman, T.I., von Borstel, R.C., Hastings, P.J. Gene (1992)
- Expression of plasmid R388-encoded type II dihydrofolate reductase as a dominant selective marker in Saccharomyces cerevisiae. Miyajima, A., Miyajima, I., Arai, K., Arai, N. Mol. Cell. Biol. (1984)
- Hsp60-independent protein folding in the matrix of yeast mitochondria. Rospert, S., Looser, R., Dubaquie, Y., Matouschek, A., Glick, B.S., Schatz, G. EMBO J. (1996)
- Sequence of a dihydrofolate reductase-encoding gene from Candida albicans. Daly, S., Mastromei, G., Yacoub, A., Lorenzetti, R. Gene (1994)
- Subcellular locations of MOD5 proteins: mapping of sequences sufficient for targeting to mitochondria and demonstration that mitochondrial and nuclear isoforms commingle in the cytosol. Boguta, M., Hunter, L.A., Shen, W.C., Gillman, E.C., Martin, N.C., Hopper, A.K. Mol. Cell. Biol. (1994)
- Analysis of nucleo-cytoplasmic transport in a thermosensitive mutant of nuclear pore protein NSP1. Nehrbass, U., Fabre, E., Dihlmann, S., Herth, W., Hurt, E.C. Eur. J. Cell Biol. (1993)
- Influence of the nuclear gene tmp3 on the loss of mitochondrial genes in Saccharomyces cerevisiae. Zelikson, R., Luzzati, M. Mol. Cell. Biol. (1982)
- Mutagenesis of dihydrofolate reductase from Plasmodium falciparum: analysis in Saccharomyces cerevisiae of triple mutant alleles resistant to pyrimethamine or WR99210. Ferlan, J.T., Mookherjee, S., Okezie, I.N., Fulgence, L., Sibley, C.H. Mol. Biochem. Parasitol. (2001)
- Inhibition studies of sulfonamide-containing folate analogs in yeast. Patel, O., Satchell, J., Baell, J., Fernley, R., Coloe, P., Macreadie, I. Microb. Drug Resist. (2003)