The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

ERG24  -  delta(14)-sterol reductase

Saccharomyces cerevisiae S288c

Synonyms: C-14 sterol reductase, Delta(14)-sterol reductase, N0593, Sterol C14-reductase, YNL280C
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on ERG24


Biological context of ERG24

  • We demonstrate that erg2 and erg24 mutants are viable in the deletion consortium background but are lethal when combined in the same haploid strain [4].
  • The wild-type ERG24 gene was cloned by complementation onto a 12-kb fragment from a yeast genomic library, and subsequently subcloned onto a 2.4-kb fragment [5].

Associations of ERG24 with chemical compounds


Other interactions of ERG24


Analytical, diagnostic and therapeutic context of ERG24


  1. Candida albicans sterol C-14 reductase, encoded by the ERG24 gene, as a potential antifungal target site. Jia, N., Arthington-Skaggs, B., Lee, W., Pierson, C.A., Lees, N.D., Eckstein, J., Barbuch, R., Bard, M. Antimicrob. Agents Chemother. (2002) [Pubmed]
  2. Aerobic isolation of an ERG24 null mutant of Saccharomyces cerevisiae. Crowley, J.H., Smith, S.J., Leak, F.W., Parks, L.W. J. Bacteriol. (1996) [Pubmed]
  3. Cloning and sequence analysis of an ERG24 homolog from Schizosaccharomyces pombe. Smith, S. Gene (1995) [Pubmed]
  4. Synthetically Lethal Interactions Involving Loss of the Yeast ERG24: The Sterol C-14 Reductase Gene. Shah Alam Bhuiyan, M., Eckstein, J., Barbuch, R., Bard, M. Lipids (2007) [Pubmed]
  5. Cloning, sequencing, and disruption of the gene encoding sterol C-14 reductase in Saccharomyces cerevisiae. Lorenz, R.T., Parks, L.W. DNA Cell Biol. (1992) [Pubmed]
  6. The identification of a gene family in the Saccharomyces cerevisiae ergosterol biosynthesis pathway. Lai, M.H., Bard, M., Pierson, C.A., Alexander, J.F., Goebl, M., Carter, G.T., Kirsch, D.R. Gene (1994) [Pubmed]
  7. Isolation, characterization, and regulation of the Candida albicans ERG27 gene encoding the sterol 3-keto reductase. Pierson, C.A., Jia, N., Mo, C., Lees, N.D., Sturm, A.M., Eckstein, J., Barbuct, R., Bard, M. Med. Mycol. (2004) [Pubmed]
  8. The sterol C-14 reductase encoded by the Neurospora crassa erg-3 gene: essential charged and polar residues identified by site-specific mutagenesis. Prakash, A., Kasbekar, D.P. Mol. Genet. Genomics (2002) [Pubmed]
WikiGenes - Universities