Gene Review:
mexR - multidrug resistance operon repressor MexR
Pseudomonas aeruginosa PAO1
- Mutations in PA3574 (nalD) lead to increased MexAB-OprM expression and multidrug resistance in laboratory and clinical isolates of Pseudomonas aeruginosa. Sobel, M.L., Hocquet, D., Cao, L., Plesiat, P., Poole, K. Antimicrob. Agents Chemother. (2005)
- Ciprofloxacin susceptibility of Pseudomonas aeruginosa isolates from keratitis. Lomholt, J.A., Kilian, M. The British journal of ophthalmology. (2003)
- Clinical strains of Pseudomonas aeruginosa overproducing MexAB-OprM and MexXY efflux pumps simultaneously. Llanes, C., Hocquet, D., Vogne, C., Benali-Baitich, D., Neuwirth, C., Plésiat, P. Antimicrob. Agents Chemother. (2004)
- Genetic and phenotypic variations of a resistant Pseudomonas aeruginosa epidemic clone. Hocquet, D., Bertrand, X., Köhler, T., Talon, D., Plésiat, P. Antimicrob. Agents Chemother. (2003)
- In vivo emergence of multidrug-resistant mutants of Pseudomonas aeruginosa overexpressing the active efflux system MexA-MexB-OprM. Ziha-Zarifi, I., Llanes, C., Köhler, T., Pechere, J.C., Plesiat, P. Antimicrob. Agents Chemother. (1999)
- Expression of the multidrug resistance operon mexA-mexB-oprM in Pseudomonas aeruginosa: mexR encodes a regulator of operon expression. Poole, K., Tetro, K., Zhao, Q., Neshat, S., Heinrichs, D.E., Bianco, N. Antimicrob. Agents Chemother. (1996)
- The mexR repressor of the mexAB-oprM multidrug efflux operon in Pseudomonas aeruginosa: characterization of mutations compromising activity. Adewoye, L., Sutherland, A., Srikumar, R., Poole, K. J. Bacteriol. (2002)
- Carbapenem resistance mechanisms in Pseudomonas aeruginosa: alterations of porin OprD and efflux proteins do not fully explain resistance patterns observed in clinical isolates. El Amin, N., Giske, C.G., Jalal, S., Keijser, B., Kronvall, G., Wretlind, B. APMIS (2005)
- Mutation in mexR-gene leading to drug resistance in corneal keratitis in human. Suman, G., Khan, M., Sabitha, K., Jamil, K. Indian J. Exp. Biol. (2006)
- Mechanisms of quinolone resistance in clinical strains of Pseudomonas aeruginosa. Jalal, S., Wretlind, B. Microb. Drug Resist. (1998)
- Organic solvent-tolerant mutants of Pseudomonas aeruginosa display multiple antibiotic resistance. Li, X.Z., Poole, K. Can. J. Microbiol. (1999)