Gene Review:
nfxB - transcriptional regulator NfxB
Pseudomonas aeruginosa PAO1
- Outer membrane proteins responsible for multiple drug resistance in Pseudomonas aeruginosa. Masuda, N., Sakagawa, E., Ohya, S. Antimicrob. Agents Chemother. (1995)
- Purification and characterization of the Pseudomonas aeruginosa NfxB protein, the negative regulator of the nfxB gene. Shiba, T., Ishiguro, K., Takemoto, N., Koibuchi, H., Sugimoto, K. J. Bacteriol. (1995)
- Mutator effects in Escherichia coli caused by the expression of specific foreign genes. Gabrovsky, V., Yamamoto, M.L., Miller, J.H. J. Bacteriol. (2005)
- Overexpression of the mexC-mexD-oprJ efflux operon in nfxB-type multidrug-resistant strains of Pseudomonas aeruginosa. Poole, K., Gotoh, N., Tsujimoto, H., Zhao, Q., Wada, A., Yamasaki, T., Neshat, S., Yamagishi, J., Li, X.Z., Nishino, T. Mol. Microbiol. (1996)
- Hypersusceptibility of the Pseudomonas aeruginosa nfxB mutant to beta-lactams due to reduced expression of the ampC beta-lactamase. Masuda, N., Sakagawa, E., Ohya, S., Gotoh, N., Nishino, T. Antimicrob. Agents Chemother. (2001)
- Cross-resistance between triclosan and antibiotics in Pseudomonas aeruginosa is mediated by multidrug efflux pumps: exposure of a susceptible mutant strain to triclosan selects nfxB mutants overexpressing MexCD-OprJ. Chuanchuen, R., Beinlich, K., Hoang, T.T., Becher, A., Karkhoff-Schweizer, R.R., Schweizer, H.P. Antimicrob. Agents Chemother. (2001)
- Purification of a 54-kilodalton protein (OprJ) produced in NfxB mutants of Pseudomonas aeruginosa and production of a monoclonal antibody specific to OprJ. Hosaka, M., Gotoh, N., Nishino, T. Antimicrob. Agents Chemother. (1995)
- Quantitative correlation between susceptibility and OprJ production in NfxB mutants of Pseudomonas aeruginosa. Masuda, N., Gotoh, N., Ohya, S., Nishino, T. Antimicrob. Agents Chemother. (1996)
- Mutations producing resistance to norfloxacin in Pseudomonas aeruginosa. Hirai, K., Suzue, S., Irikura, T., Iyobe, S., Mitsuhashi, S. Antimicrob. Agents Chemother. (1987)
- Characterization of the MexC-MexD-OprJ multidrug efflux system in DeltamexA-mexB-oprM mutants of Pseudomonas aeruginosa. Gotoh, N., Tsujimoto, H., Tsuda, M., Okamoto, K., Nomura, A., Wada, T., Nakahashi, M., Nishino, T. Antimicrob. Agents Chemother. (1998)
- Fitness of in vitro selected Pseudomonas aeruginosa nalB and nfxB multidrug resistant mutants. Sánchez, P., Linares, J.F., Ruiz-Díez, B., Campanario, E., Navas, A., Baquero, F., Martínez, J.L. J. Antimicrob. Chemother. (2002)
- Cloning and nucleotide sequence of the Pseudomonas aeruginosa nfxB gene, conferring resistance to new quinolones. Okazaki, T., Hirai, K. FEMS Microbiol. Lett. (1992)
- Intrinsic resistance to inhibitors of fatty acid biosynthesis in Pseudomonas aeruginosa is due to efflux: application of a novel technique for generation of unmarked chromosomal mutations for the study of efflux systems. Schweizer, H.P. Antimicrob. Agents Chemother. (1998)
- Occurrence of the nfxB type mutation in clinical isolates of Pseudomonas aeruginosa. Jakics, E.B., Iyobe, S., Hirai, K., Fukuda, H., Hashimoto, H. Antimicrob. Agents Chemother. (1992)
- Interplay between the efflux pump and the outer membrane permeability barrier in fluorescent dye accumulation in Pseudomonas aeruginosa. Germ, M., Yoshihara, E., Yoneyama, H., Nakae, T. Biochem. Biophys. Res. Commun. (1999)
- Functional replacement of OprJ by OprM in the MexCD-OprJ multidrug efflux system of Pseudomonas aeruginosa. Gotoh, N., Tsujimoto, H., Nomura, A., Okamoto, K., Tsuda, M., Nishino, T. FEMS Microbiol. Lett. (1998)
- Mechanisms of high-level resistance to quinolones in urinary tract isolates of Pseudomonas aeruginosa. Yoshida, T., Muratani, T., Iyobe, S., Mitsuhashi, S. Antimicrob. Agents Chemother. (1994)
- Mechanisms of quinolone resistance in clinical strains of Pseudomonas aeruginosa. Jalal, S., Wretlind, B. Microb. Drug Resist. (1998)