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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Menstruation Disturbances

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Disease relevance of Menstruation Disturbances


High impact information on Menstruation Disturbances


Chemical compound and disease context of Menstruation Disturbances

  • The results show that the patterns of plasma estrogen in thyrotoxic women with hypomenorrhea were similar to those in euthyroid women, although the levels in the thyrotoxic women were significantly elevated (P less than 0.001) [9].

Biological context of Menstruation Disturbances

  • In the population studied most of the patients had tubal obstruction and high CA 125 serum concentrations during menstruation, which revokes the theory that the menstrual rise of CA 125 is due only to retrograde menstruation [10].

Anatomical context of Menstruation Disturbances

  • Plasma levels of estrogen were measured daily by radioimmunoassay for 28 consecutive days in 12 healthy euthyroid women and 15 thyrotoxic women (10 with hypomenorrhea and 5 with amenorrhea) before commencement of therapy (except in one case) in an effort to increase understanding of the relationship between the thyroid gland and ovarian function [9].
  • It is remarkable that 8 patients had a bicornuate uterus, and of them 7 had oligo- and/or hypomenorrhea [11].

Gene context of Menstruation Disturbances


  1. Suppression of matrix metalloproteinases inhibits establishment of ectopic lesions by human endometrium in nude mice. Bruner, K.L., Matrisian, L.M., Rodgers, W.H., Gorstein, F., Osteen, K.G. J. Clin. Invest. (1997) [Pubmed]
  2. Prevalence of hyperprolactinemia in schizophrenic patients treated with conventional antipsychotic medications or risperidone. Kinon, B.J., Gilmore, J.A., Liu, H., Halbreich, U.M. Psychoneuroendocrinology (2003) [Pubmed]
  3. Dysmenorrhea after bilateral tubal ligation: a case of retrograde menstruation. Morrissey, K., Idriss, N., Nieman, L., Winkel, C., Stratton, P. Obstetrics and gynecology. (2002) [Pubmed]
  4. Vascular endothelial growth factor mRNA in eutopic and ectopic endometrium. Kressin, P., Wolber, E.M., Wodrich, H., Meyhöfer-Malik, A., Buchweitz, O., Diedrich, K., Malik, E. Fertil. Steril. (2001) [Pubmed]
  5. Vascular endothelial growth factor (VEGF) in endometriosis. Donnez, J., Smoes, P., Gillerot, S., Casanas-Roux, F., Nisolle, M. Hum. Reprod. (1998) [Pubmed]
  6. High CA-125 concentrations in peritoneal fluid of normal cyclic women with various infertility-related factors as demonstrated with two-step immunoradiometric assay. Kruitwagen, R.F., Thomas, C., Poels, L.G., Koster, A.M., Willemsen, W.N., Rolland, R. Fertil. Steril. (1991) [Pubmed]
  7. Systemic lupus erythematosus and reproductive function: a case-control study. Grimes, D.A., LeBolt, S.A., Grimes, K.R., Wingo, P.A. Am. J. Obstet. Gynecol. (1985) [Pubmed]
  8. Naproxen sodium in dysmenorrhea. Its influence in allowing continuation of work/school activities. Hanson, F.W., Izu, A., Henzl, M.R. Obstetrics and gynecology. (1978) [Pubmed]
  9. Plasma estrogens in euthyroid and thyrotoxic women. Akande, E.O. Am. J. Obstet. Gynecol. (1975) [Pubmed]
  10. Fluctuations in CA 125 and CA 15-3 serum concentrations during spontaneous ovulatory cycles. Bon, G.G., Kenemans, P., Dekker, J.J., Hompes, P.G., Verstraeten, R.A., van Kamp, G.J., Schoemaker, J. Hum. Reprod. (1999) [Pubmed]
  11. Infertility factors. Their relative importance and share in an unselected material of infertility patients. Sørensen, S.S. Acta obstetricia et gynecologica Scandinavica. (1980) [Pubmed]
  12. Endometriosis: its association with retrograde menstruation, dysmenorrhoea and tubal pathology. Liu, D.T., Hitchcock, A. British journal of obstetrics and gynaecology. (1986) [Pubmed]
  13. Premenarchal and postmenarchal girls with insulin-dependent diabetes mellitus: ovarian and other organ-specific autoantibodies, menstrual cycle. Snajderová, M., Martínek, J., Horejsí, J., Nováková, D., Lebl, J., Kolousková, S. Journal of pediatric and adolescent gynecology. (1999) [Pubmed]
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