Disease relevance of Anisometropia

• Ambyopia is usually associated with either a strabismus (eye misalignment) or anisometropia (unequal refractive error) [1].
• The median age at presentation for strabismic amblyopia (3.64 years) was significantly lower than for combined strabismus and anisometropia (4.68 years) and anisometropia (6.27 years) [2].
• Myopia (< -0.5 diopter [D] spherical equivalent) declined with age, whereas hyperopia (> +0.5 D), astigmatism (> 0.5 D of cylinder), and anisometropia (> 1.0 D between eyes) increased with age [3].
• There is a high prevalence of strabismus in children with Down syndrome (29% of the total group), which cannot be attributed to the presence of hypermetropia or anisometropia [4].
• BACKGROUND: Periorbital capillary hemangiomas of childhood can produce ptosis, strabismus, and anisometropia, resulting in amblyopia [5].

Psychiatry related information on Anisometropia

• CONCLUSIONS: When employing occlusion therapy for amblyopia (due to anisometropia, small-angle or intermittent strabismus, or a combination), as VA improves, stereopsis generally also improves [6].

High impact information on Anisometropia

• Prevalence of myopia showed no clear trend with increasing age, whereas hyperopia, astigmatism, and anisometropia all increased monotonically [7].
• RESULTS: The mean SE in patients with Cohen syndrome older than 10 years was -9.35 D; the mean cylinder power, +1.70 D; and the mean anisometropia, 0.53 D [8].
• PARTICIPANTS: Nine patients had strabismic amblyopia, ten had anisometropia, six had a combination of anisometropia and strabismus, and three had deprivation amblyopia due to monocular congenital cataract [9].
• The procedure was performed with the Summit Autonomous LADARVision 4000 excimer laser (Alcon Laboratories, Inc.) in the amblyopic eye for the correction of anisometropia or in both eyes [10].
• The most common refractive error was myopia (4.5%), followed by anisometropia (3.1%), hyperopia (2.9%), and astigmatism (1.0%) [11].

Chemical compound and disease context of Anisometropia

• No statistical difference was found in spherical refractive error, astigmatism, or anisometropia between the cocaine-exposed cohorts and the control group (N = 100) [12].
• Steroid injection versus conservative treatment of anisometropia amblyopia in juvenile adnexal hemangioma [13].

Biological context of Anisometropia

• Visual evoked potentials (VEPs) produced by pattern reversal were compared with those elicited by onset of motion in 37 amblyopic children (20 with anisometropic amblyopia, seven with strabismic amblyopia and 10 with both anisometropia and strabismus) [14].
• After consideration of various clinical investigations the significant factors identified in patients showing a RAPD were: anisometropia, early age of onset where strabismus was present, level of visual acuity following treatment, longer period of occlusion therapy [15].

Anatomical context of Anisometropia

• We investigated the nature of residual binocular interactions in the striate cortex (V1) of monkey models for the two most common causes of visual dysfunction in young children, specifically anisometropia and strabismus [16].

Gene context of Anisometropia

• PURPOSE: To determine the prevalence rates of myopia, hyperopia, astigmatism, and anisometropia in a prevalence survey of adults in Sumatra, Indonesia [17].
• Surgical response (Delta/mm recession performed) increased with the magnitude of both preoperative deviation (P<0.001) and anisometropia (P<0.001); the effect of deviation on surgical response was reduced by amblyopia (P=0.02) [18].
• PRK for myopic anisometropia [19].
• Individually no distinct association was noticed between various CSF-types and different groups of amblyopia, but on average in anisometropia the deficiency at low spatial frequencies was more pronounced than in purely strabismic cases [20].

Analytical, diagnostic and therapeutic context of Anisometropia

• PURPOSE: To evaluate the results of excimer laser photorefractive keratectomy (PRK) for myopia in pediatric eyes with amblyopia resulting from anisometropia [21].
• CONCLUSIONS: Special care should be taken of patients who have a preoperative history of strabismus surgery, an overcorrection or undercorrection in 1 or both eyes, or anisometropia and of those who are unhappy with contact lenses [22].
• BACKGROUND: High amounts of myopia can frequently produce anisometropia and limit visual rehabilitation by conventional means in eyes with clear corneal grafts [23].
• Craniopharyngioma should be considered in the differential diagnosis of every child with amblyopia, particularly when no amblyogenic factors such as anisometropia or strabismus are present [24].

References