Disease relevance of Erythrocebus

• Chronic stavudine exposure induces hepatic mitochondrial toxicity in adult Erythrocebus patas monkeys [1].

High impact information on Erythrocebus

• Northern blot analysis of poly(A)+ RNA isolated from the liver of an untreated and a phenobarbital-treated Erythrocebus patas monkey with 5'-specific probes for each clone indicated that the HUG-Br2-encoded message is induced two fold, but that for HUG-Br1 is not [2].
• Fifty monkeys of the species Erythrocebus patas were fed a control monkey chow, a semi-synthetic diet containing 25% lard, or a semisynthetic diet containing 25% lard and 0.5% cholesterol for 2 years [3].
• Male and female patas (Erythrocebus patas) and cynomolgus (Macaca fascicularis) monkeys were treated with phenobarbitone (PB) and examined for the induction of various cytochrome P450 (P450)-mediated drug metabolizing enzymes [4].
• Isolation and partial characterization of the low-molecular-mass zinc/cadmium-binding protein from the testes of the patas monkey (Erythrocebus patas). Distinction from metallothionein [5].
• The NH2-terminal sequence of the M. fascicularis apoA-I is identical with that of another Old World species, Erythrocebus patas, and differs from human apoA-I at only 4 of the first 24 residues [6].

Biological context of Erythrocebus

• A previous attempt to model transplacental cisplatin exposure and genotoxicity employed several pregnant Erythrocebus patas monkeys; most of the animals were exposed near the end of gestation and cisplatin-DNA adduct analyses included only genomic DNA [7].

Anatomical context of Erythrocebus

• This report describes a study that took advantage of the unique reactivity of the patas monkey (Erythrocebus patas) to dihydrostreptomycin-sulfate (DHSM) to investigate the effects of selective outer hair cell (OHC) lesions on psychophysical tuning curves (PTC) [8].
• The remarkable susceptibility of the inner ear of the patas monkey (Erythrocebus patas) to the ototoxic action of dihydrostreptomycin (DHSM) (and streptomycin (SM)) is well established in this paper and affords a rare example of a species-specific reaction to a restricted class of compounds within the aminoglycoside group of antibiotics [9].
• Coexisting tricuspid valve dysplasia and ventricular septal defect in a young patas monkey (Erythrocebus patas) [10].

Associations of Erythrocebus with chemical compounds

• To model human transplacental ZDV and 3TC exposures, experiments were performed in Erythrocebus patas monkeys given human-equivalent drug exposure protocols [11].
• Effects of d-norgestrel-releasing intracervical devices in the nonhuman primate, Erythrocebus patas [12].
• Transplacental effects of ethylnitrosourea in a nonhuman primate, Erythrocebus patas [13].

Analytical, diagnostic and therapeutic context of Erythrocebus

• Effect of ovariectomy on response to dietary cholesterol in patas monkeys (Erythrocebus patas) [14].

References