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MeSH Review


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Disease relevance of Toxocariasis


High impact information on Toxocariasis

  • Mebendazole in toxocariasis [6].
  • Lafoensia pacari extract inhibits IL-5 production in toxocariasis [7].
  • CONCLUSIONS: These data suggest, first, that patients presenting unexplained allergic syndromes should be checked for helminthiases, even if blood eosinophilia is lacking, and, second, in such subjects displaying positive toxocariasis immunodiagnosis, ECP assessment would be a useful marker to distinguish between active and past toxocaral disease [8].
  • Sera from mice infected with the parasite also contained antibodies to rTc-CPL-1 as did sera from nine patients with proven toxocariasis; control sera did not [9].
  • These results suggest that MMP-9 may be associated with the inflammatory reaction to larval toxocariasis during early migration, and may therefore be a useful marker during T. canis larvae migration [10].

Chemical compound and disease context of Toxocariasis


Biological context of Toxocariasis


Gene context of Toxocariasis

  • Toxocariasis. A possible cause of the Palm Island mystery disease [18].
  • For human population IACE was evaluated using sera from 440 patients with clinical signs of toxocariasis and the cut-off value was established with 60 serum samples from apparently healthy individuals [19].
  • This case illustrates that toxocariasis should be considered as a rare differential diagnostic possibility for multiple liver lesions and multifocal peripheral pulmonary opacities in young children with Wilms tumor [20].

Analytical, diagnostic and therapeutic context of Toxocariasis


  1. Meningomyelitis in a case of toxocariasis with markedly isolated CSF eosinophilia and an MRI-documented thoracic cord lesion. Strupp, M., Pfister, H.W., Eichenlaub, S., Arbusow, V. J. Neurol. (1999) [Pubmed]
  2. Vasoproliferative tumors of the ocular fundus. Classification and clinical manifestations in 103 patients. Shields, C.L., Shields, J.A., Barrett, J., De Potter, P. Arch. Ophthalmol. (1995) [Pubmed]
  3. Highlights of human toxocariasis. Magnaval, J.F., Glickman, L.T., Dorchies, P., Morassin, B. Korean J. Parasitol. (2001) [Pubmed]
  4. Serologic evidence of toxocariasis in northeast Brazil. Virginia, P., Nagakura, K., Ferreira, O., Tateno, S. Jpn. J. Med. Sci. Biol. (1991) [Pubmed]
  5. Palm island reconsidered. Was it copper poisoning? Prociv, P. Australian and New Zealand journal of medicine. (1987) [Pubmed]
  6. Mebendazole in toxocariasis. Bekhti, A. Ann. Intern. Med. (1984) [Pubmed]
  7. Lafoensia pacari extract inhibits IL-5 production in toxocariasis. Rogerio, A.P., Sá-Nunes, A., Albuquerque, D.A., Anibal, F.F., Medeiros, A.I., Machado, E.R., Souza, A.O., Prado, J.C., Faccioli, L.H. Parasite Immunol. (2003) [Pubmed]
  8. Eosinophil cationic protein as a possible marker of active human Toxocara infection. Magnaval, J.F., Berry, A., Fabre, R., Morassin, B. Allergy (2001) [Pubmed]
  9. Characterisation of Tc-cpl-1, a cathepsin L-like cysteine protease from Toxocara canis infective larvae. Loukas, A., Selzer, P.M., Maizels, R.M. Mol. Biochem. Parasitol. (1998) [Pubmed]
  10. Induction of matrix metalloproteinase-9 in mice during Toxocara canis larvae migration. Lai, S.C., Chen, K.M., Chen, H.C., Lee, H.H. Parasitol. Res. (2005) [Pubmed]
  11. "Covert toxocariasis" in a child treated with low-dose diethylcarbamazine. Rasmussen, L.N., Dirdal, M., Birkebaek, N.H. Acta Paediatr. (1993) [Pubmed]
  12. Treatment of ocular toxocariasis with albendazole. Barisani-Asenbauer, T., Maca, S.M., Hauff, W., Kaminski, S.L., Domanovits, H., Theyer, I., Auer, H. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. (2001) [Pubmed]
  13. Anthelmintic effect of levamisole hydrochloride or ivermectin on tissue toxocariasis of mice. Carrillo, M., Barriga, O.O. Am. J. Vet. Res. (1987) [Pubmed]
  14. The effect of cyclosporin A (CSA) on murine visceral toxocariasis canis. el-Ganayni, G.A., Handousa, A.E. Journal of the Egyptian Society of Parasitology. (1992) [Pubmed]
  15. Treatment of Toxocara canis infections in mice with liposome-incorporated benzimidazole carbamates and immunomodulator glucan. Hrckova, G., Velebný, S. J. Helminthol. (2001) [Pubmed]
  16. Antibody responses to Toxocara canis using sera from parasite-infected mice and protection from toxocariasis by immunisation with ES antigens. Nicholas, W.L., Stewart, A.C., Mitchell, G.F. The Australian journal of experimental biology and medical science. (1984) [Pubmed]
  17. Evaluation of an enzymatic immunohistochemical technique in human trichinellosis. Ben, G.J., Malmassari, S.L., Nuñez, G.G., Costantino, S.N., Venturiello, S.M. J. Helminthol. (1997) [Pubmed]
  18. Toxocariasis. A possible cause of the Palm Island mystery disease. Moorhouse, D.E. Med. J. Aust. (1982) [Pubmed]
  19. Toxocariasis: serological diagnosis by indirect antibody competition ELISA. Nunes, C.M., Tundisi, R.N., Heinemann, M.B., Ogassawara, S., Richtzenhain, L.J. Rev. Inst. Med. Trop. Sao Paulo (1999) [Pubmed]
  20. Visceral larval migrans masquerading as metastatic disease in a toddler with Wilms tumor. Anderson, A., Fordham, L.A., Bula, M.L., Blatt, J. Pediatric radiology. (2006) [Pubmed]
  21. Enzyme-linked immunosorbent assay for toxocariasis, its application to the sera of children. Matsumura, K., Endo, R. Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. 1. Abt. Originale A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie = International journal of microbiology and hygiene. A, Medical microbiology, infectiousdiseases, para... (1982) [Pubmed]
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