Disease relevance of Retinal Necrosis Syndrome, Acute

• Six patients (8 eyes) fulfilling absolute and relative criteria for acute retinal necrosis optic neuropathy were treated with intravenous acyclovir as well as optic nerve sheath decompression, and, in addition, some of these patients also underwent vitreoretinal surgery [1].
• Anti-herpes simplex virus type 2 antibody was positive and anti-herpes simplex virus type 1 antibody was negative in the sera of the seven patients with herpes simplex virus type 2 DNA-positive acute retinal necrosis syndrome [2].
• The purpose of this study was to examine the relationship between IFN-gamma expression and the clinical course of patients with acute retinal necrosis syndrome (ARN) associated with the varicella-zoster virus (VZV) [3].
• Hydroxyacyclovir may have applications in the treatment of deep herpetic infections, CMV retinitis, and acute retinal necrosis [4].
• CONCLUSIONS: Systemic foscarnet can be effective in the management of pediatric acute retinal necrosis caused by HSV-2 when there is an atypical response to conventional acyclovir treatment [5].

High impact information on Retinal Necrosis Syndrome, Acute

• Famciclovir in AIDS-related acute retinal necrosis [6].
• Treatment of the acute retinal necrosis syndrome with intravenous acyclovir [7].
• The acute retinal necrosis syndrome. Part 2: Histopathology and etiology [8].
• Polymerase chain reaction as a rapid diagnostic tool for therapy of acute retinal necrosis syndrome [9].
• However, Fas and FasL expression was absent in the biopsy specimens with acute retinal necrosis, and little Fas or FasL was noted on infiltrating lymphocytes [10].

Chemical compound and disease context of Retinal Necrosis Syndrome, Acute

• Acute retinal necrosis following epidural steroid injections [11].
• CONCLUSION: Distinct features of acute retinal necrosis and progressive outer retinal necrosis do not necessarily reflect systemic factors, and they may be variant manifestations of the same underlying infection [12].
• Acute retinal necrosis (ARN) is a rare syndrome with characteristic fundal appearances which can have devastating effects on vision [13].
• PURPOSE: To report the use of intravenous (IV) antiviral agents and intravitreal ganciclovir injections in three immunocompetent patients with severe acute retinal necrosis (ARN) [14].
• Oral valacyclovir in the treatment of acute retinal necrosis syndrome [15].

Biological context of Retinal Necrosis Syndrome, Acute

• An association between acute retinal necrosis syndrome and HLA-DQw7 and phenotype Bw62, DR4 [16].

Anatomical context of Retinal Necrosis Syndrome, Acute

• The acute retinal necrosis (ARN) syndrome is an increasingly occurring entity characterized by the triad of acute confluent peripheral retinitis with papillitis and anterior-chamber uveitis [17].

Gene context of Retinal Necrosis Syndrome, Acute

• PURPOSE: To report a case of unilateral varicella-zoster virus (VZV) necrotizing retinopathy that progressed from outer retinitis with features of progressive outer retinal necrosis (PORN) to typical acute retinal necrosis (ARN) in an HIV-negative patient with a transient decrease in CD4 lymphocyte counts and CD4/CD8 ratio [18].
• Herpes simplex virus type 2 acute retinal necrosis in a patient with systemic lupus erythematosus [19].

References