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MeSH Review

Optic Nerve Diseases

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Disease relevance of Optic Nerve Diseases


High impact information on Optic Nerve Diseases


Chemical compound and disease context of Optic Nerve Diseases


Biological context of Optic Nerve Diseases


Anatomical context of Optic Nerve Diseases


Gene context of Optic Nerve Diseases


Analytical, diagnostic and therapeutic context of Optic Nerve Diseases


  1. Two novel pathogenic mitochondrial DNA mutations affecting organelle number and protein synthesis. Is the tRNA(Leu(UUR)) gene an etiologic hot spot? Moraes, C.T., Ciacci, F., Bonilla, E., Jansen, C., Hirano, M., Rao, N., Lovelace, R.E., Rowland, L.P., Schon, E.A., DiMauro, S. J. Clin. Invest. (1993) [Pubmed]
  2. Leber's hereditary optic neuropathy mitochondrial DNA mutations in multiple sclerosis. Kellar-Wood, H., Robertson, N., Govan, G.G., Compston, D.A., Harding, A.E. Ann. Neurol. (1994) [Pubmed]
  3. Fine mapping of the autosomal dominant juvenile open angle glaucoma (GLC1A) region and evaluation of candidate genes. Sunden, S.L., Alward, W.L., Nichols, B.E., Rokhlina, T.R., Nystuen, A., Stone, E.M., Sheffield, V.C. Genome Res. (1996) [Pubmed]
  4. Adenosine triphosphate deficiency: a genre of optic neuropathy. Rizzo, J.F. Neurology (1995) [Pubmed]
  5. Optic neuropathy associated with rapid tightening of blood glucose control. Knight, G., Talbot, J.F., Ward, J.D. Lancet (1984) [Pubmed]
  6. Hydroxycobalamin for ethambutol-induced optic neuropathy. Guerra, R., Casu, L. Lancet (1981) [Pubmed]
  7. An example of Leber hereditary optic neuropathy not involving a mutation in the mitochondrial ND4 gene. Howell, N., McCullough, D. Am. J. Hum. Genet. (1990) [Pubmed]
  8. The role of the ND5 gene in LHON: characterization of a new, heteroplasmic LHON mutation. Mayorov, V., Biousse, V., Newman, N.J., Brown, M.D. Ann. Neurol. (2005) [Pubmed]
  9. SOD2 gene transfer protects against optic neuropathy induced by deficiency of complex I. Qi, X., Lewin, A.S., Sun, L., Hauswirth, W.W., Guy, J. Ann. Neurol. (2004) [Pubmed]
  10. Toluene optic neuropathy. Keane, J.R. Ann. Neurol. (1978) [Pubmed]
  11. Chlorpropamide-induced optic neuropathy. Wymore, J., Carter, J.E. Arch. Intern. Med. (1982) [Pubmed]
  12. Methanol optic neuropathy: a histopathological study. Sharpe, J.A., Hostovsky, M., Bilbao, J.M., Rewcastle, N.B. Neurology (1982) [Pubmed]
  13. Evaluation of inducible nitric oxide synthase in glaucomatous optic neuropathy and pressure-induced optic nerve damage. Pang, I.H., Johnson, E.C., Jia, L., Cepurna, W.O., Shepard, A.R., Hellberg, M.R., Clark, A.F., Morrison, J.C. Invest. Ophthalmol. Vis. Sci. (2005) [Pubmed]
  14. Genetic heterogeneity of primary open angle glaucoma and ocular hypertension: linkage to GLC1A associated with an increased risk of severe glaucomatous optic neuropathy. Brézin, A.P., Béchetoille, A., Hamard, P., Valtot, F., Berkani, M., Belmouden, A., Adam, M.F., Dupont de Dinechin, S., Bach, J.F., Garchon, H.J. J. Med. Genet. (1997) [Pubmed]
  15. Visual function in recovered ethambutol optic neuropathy. Woung, L.C., Jou, J.R., Liaw, S.L. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. (1995) [Pubmed]
  16. Optic neuropathy following amiodarone therapy. Sreih, A.G., Schoenfeld, M.H., Marieb, M.A. Pacing and clinical electrophysiology : PACE. (1999) [Pubmed]
  17. Use of contrast sensitivity measurement in the detection of subclinical ethambutol toxic optic neuropathy. Salmon, J.F., Carmichael, T.R., Welsh, N.H. The British journal of ophthalmology. (1987) [Pubmed]
  18. Acute optic neuropathy induced by thinner sniffing: inhalation of mixed organic solvent containing methyl alcohol and methyl acetate. Ogawa, Y., Takatsuki, R., Uema, T., Seki, Y., Hiramatsu, K., Okayama, A., Morimoto, K., Kaneko, Z. Industrial health. (1988) [Pubmed]
  19. Rhodanese isozymes in three subjects with Leber's optic neuropathy. Whitehouse, D.B., Poole, C.J., Kind, P.R., Hopkinson, D.A. J. Med. Genet. (1989) [Pubmed]
  20. Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human optic nerve head astrocytes. Agapova, O.A., Ricard, C.S., Salvador-Silva, M., Hernandez, M.R. Glia (2001) [Pubmed]
  21. Optic neuropathy in sarcoidosis. Graham, E.M., Ellis, C.J., Sanders, M.D., McDonald, W.I. J. Neurol. Neurosurg. Psychiatr. (1986) [Pubmed]
  22. Optic nerve changes in zinc-deficient rats. Gong, H., Amemiya, T. Exp. Eye Res. (2001) [Pubmed]
  23. Chloramphenicol optic neuropathy. Godel, V., Nemet, P., Lazar, M. Arch. Ophthalmol. (1980) [Pubmed]
  24. The mitochondrial ND6 gene is a hot spot for mutations that cause Leber's hereditary optic neuropathy. Chinnery, P.F., Brown, D.T., Andrews, R.M., Singh-Kler, R., Riordan-Eva, P., Lindley, J., Applegarth, D.A., Turnbull, D.M., Howell, N. Brain (2001) [Pubmed]
  25. Cyclooxygenase-1 and cyclooxygenase-2 in the human optic nerve head. Neufeld, A.H., Hernandez, M.R., Gonzalez, M., Geller, A. Exp. Eye Res. (1997) [Pubmed]
  26. Elevated plasma levels of interleukin 8 in patients with acute anterior ischaemic optic neuropathy. Goldenberg-Cohen, N., Kramer, M., Bahar, I., Monselise, Y., Weinberger, D. The British journal of ophthalmology. (2004) [Pubmed]
  27. Optineurin in primary open angle glaucoma. Sarfarazi, M., Rezaie, T. Ophthalmology clinics of North America. (2003) [Pubmed]
  28. Endothelin-1 synthesis and secretion in human retinal pigment epithelial cells (ARPE-19): differential regulation by cholinergics and TNF-alpha. Narayan, S., Prasanna, G., Krishnamoorthy, R.R., Zhang, X., Yorio, T. Invest. Ophthalmol. Vis. Sci. (2003) [Pubmed]
  29. Radiation-induced bilateral optic neuropathy in cancer of the nasopharynx. Case failure analysis and a review of the literature. Wijers, O.B., Levendag, P.C., Luyten, G.P., Bakker, B.A., Freling, N.J., Klesman-Bradley, J., Woudstra, E. Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]. (1999) [Pubmed]
  30. Spot-scanning proton radiation therapy for recurrent, residual or untreated intracranial meningiomas. Weber, D.C., Lomax, A.J., Rutz, H.P., Stadelmann, O., Egger, E., Timmermann, B., Pedroni, E.S., Verwey, J., Miralbell, R., Goitein, G. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. (2004) [Pubmed]
  31. Optical coherence tomography can measure axonal loss in patients with ethambutol-induced optic neuropathy. Zoumalan, C.I., Agarwal, M., Sadun, A.A. Graefes Arch. Clin. Exp. Ophthalmol. (2005) [Pubmed]
  32. Vitreous fluorophotometry in optic nerve disease. Braude, L.S., Cunha-Vaz, J.G., Frenkel, M. The British journal of ophthalmology. (1982) [Pubmed]
  33. Bilateral optic neuropathy after bone marrow transplantation and cyclosporin A therapy. Walter, S.H., Bertz, H., Gerling, J. Graefes Arch. Clin. Exp. Ophthalmol. (2000) [Pubmed]
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