Disease relevance of Mansonella

• Immunoelectroblotting and enzyme-linked immunosorbent assay were used to identify non-cross-reacting antigenic components of Dracunculus medinensis and the filarial worms Onchocerca volvulus, Loa loa, Wuchereria bancrofti, Brugia malayi, and Mansonella ozzardi [1].
• The use of mebendazole in the treatment of filariases due to Loa loa and Mansonella perstans [2].

High impact information on Mansonella

• Detection of the filarial parasite Mansonella streptocerca in skin biopsies by a nested polymerase chain reaction-based assay [3].
• Sera from individuals in an area of Haiti endemic for Mansonella ozzardi were analyzed for reactivity to antigens of Brugia pahangi, Dirofilaria immitis, Mansonella llewellyni or Ascaris lumbricoides using either an enzyme-linked immunosorbent assay or an indirect immunofluorescent antibody test [4].
• Case report: intraocular localization of Mansonella perstans in a patient from south Chad [5].
• Decrease in Mansonella perstans microfilaraemia after albendazole treatment [6].
• The failure of diethylcarbamazine in the treatment of Mansonella ozzardi infections [7].

Chemical compound and disease context of Mansonella

• Effects of thiabendazole in Mansonella perstans filariasis [8].

Gene context of Mansonella

• Whilst the 20 kDa antigen did not detect antibodies in the sera of Trinidadians infected with Wuncheria bancrofti or Mansonella ozzardi, this antigen detected high levels of antibodies in Indians exposed to W. bancrofti [9].
• Microfilariae of Tetrapetalonema llewellyni in raccoons of Cades Cove, Great Smoky Mountains National Park, Tennessee, USA [10].
• Four drugs, dithiazanine iodide, naphuride sodium, thiacetarsamide sodium, and diethylcarbamazine were tested against Dipetalonema gracile and Tetrapetalonema marmosetae [11].

References