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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


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Disease relevance of Boidae


High impact information on Boidae

  • In digesting pythons, the regulatory peptides neurotensin, somatostatin, motilin, and vasoactive intestinal peptide occur largely in the stomach, GIP and glucagon in the pancreas, and CCK and substance P in the small intestine [2].
  • For two weeks after feeding we quantified the CO2 exhaled by pythons and determined its isotopic 13C/12C signature [3].
  • Luminal nutrient signals for intestinal adaptation in pythons [4].
  • Normally sighted Burmese pythons exhibited average targeting angle of zero (on the midline axis of the head), but three unilaterally anophthalmic Burmese pythons targeted preferentially on the sighted side [5].
  • Pharmacokinetics and tissue concentrations of azithromycin in ball pythons (Python regius) [6].

Associations of Boidae with chemical compounds

  • CONCLUSIONS AND CLINICAL RELEVANCE: Azithromycin is well absorbed and tolerated by ball pythons [6].
  • There were no significant differences in hematologic values in samples from pythons collected in heparin or EDTA at any time point [7].
  • A new dosing schedule for gentamicin in blood pythons (Python curtus): a pharmacokinetic study [8].
  • Six pythons received a single i.m. injection of enrofloxacin at 5 mg/kg [9].
  • Therefore, amikacin (3.48 mg/kg) administered i.m. to ball pythons should produce maximum serum concentrations against most pathogenic bacteria [10].

Gene context of Boidae


Analytical, diagnostic and therapeutic context of Boidae


  1. Identification of a Bohle iridovirus thymidine kinase gene and demonstration of activity using vaccinia virus. Coupar, B.E., Goldie, S.G., Hyatt, A.D., Pallister, J.A. Arch. Virol. (2005) [Pubmed]
  2. Responses of python gastrointestinal regulatory peptides to feeding. Secor, S.M., Fehsenfeld, D., Diamond, J., Adrian, T.E. Proc. Natl. Acad. Sci. U.S.A. (2001) [Pubmed]
  3. Pythons metabolize prey to fuel the response to feeding. Starck, J.M., Moser, P., Werner, R.A., Linke, P. Proc. Biol. Sci. (2004) [Pubmed]
  4. Luminal nutrient signals for intestinal adaptation in pythons. Secor, S.M., Lane, J.S., Whang, E.E., Ashley, S.W., Diamond, J. Am. J. Physiol. Gastrointest. Liver Physiol. (2002) [Pubmed]
  5. Altered visual experience and acute visual deprivation affect predatory targeting by infrared-imaging Boid snakes. Grace, M.S., Woodward, O.M. Brain Res. (2001) [Pubmed]
  6. Pharmacokinetics and tissue concentrations of azithromycin in ball pythons (Python regius). Coke, R.L., Hunter, R.P., Isaza, R., Koch, D.E., Goatley, M.A., Carpenter, J.W. Am. J. Vet. Res. (2003) [Pubmed]
  7. Temporal effects of 3 commonly used anticoagulants on hematologic and biochemical variables in blood samples from macaws and Burmese pythons. Harr, K.E., Raskin, R.E., Heard, D.J. Veterinary clinical pathology / American Society for Veterinary Clinical Pathology. (2005) [Pubmed]
  8. A new dosing schedule for gentamicin in blood pythons (Python curtus): a pharmacokinetic study. Hilf, M., Swanson, D., Wagner, R., Yu, V.L. Res. Vet. Sci. (1991) [Pubmed]
  9. Disposition of enrofloxacin and its metabolite ciprofloxacin after intramuscular injection in juvenile Burmese pythons (Python molurus bivittatus). Young, L.A., Schumacher, J., Papich, M.G., Jacobson, E.R. J. Zoo Wildl. Med. (1997) [Pubmed]
  10. Amikacin pharmacokinetics and the effects of ambient temperature on the dosage regimen in ball pythons (Python regius). Johnson, J.H., Jensen, J.M., Brumbaugh, G.W., Boothe, D.M. J. Zoo Wildl. Med. (1997) [Pubmed]
  11. Systemic administration of local anesthetic agents to relieve neuropathic pain. Challapalli, V., Tremont-Lukats, I.W., McNicol, E.D., Lau, J., Carr, D.B. Cochrane database of systematic reviews (Online) (2005) [Pubmed]
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